scholarly journals The association between TP53 Arg72pro polymorphism and non-melanoma skin cancer risk: A meta-analysis including 7,107 subjects

2013 ◽  
Vol 58 (3) ◽  
pp. 175
Author(s):  
Bo Li ◽  
Baohong Yang ◽  
Xueling Yang ◽  
Ya Liu ◽  
Shanshan Xu
2011 ◽  
Vol 131 (1) ◽  
pp. 220-228 ◽  
Author(s):  
De-Ke Jiang ◽  
Wen-Zhang Wang ◽  
Wei-Hua Ren ◽  
Lei Yao ◽  
Bo Peng ◽  
...  

2014 ◽  
Vol 50 (15) ◽  
pp. 2649-2658 ◽  
Author(s):  
Saverio Caini ◽  
Mathieu Boniol ◽  
Giulio Tosti ◽  
Serena Magi ◽  
Matelda Medri ◽  
...  

2019 ◽  
Vol 121 (11) ◽  
pp. 973-978 ◽  
Author(s):  
Anton Pottegård ◽  
Sidsel Arnspang Pedersen ◽  
Sigrun Alba Johannesdottir Schmidt ◽  
Chaw-Ning Lee ◽  
Chao-Kai Hsu ◽  
...  

Abstract Background The antihypertensive agent hydrochlorothiazide has been associated with increased risks of non-melanoma skin cancer (NMSC) and possibly some melanoma subtypes. Previous studies were, however, conducted in predominantly Caucasian populations. We therefore examined the association between hydrochlorothiazide and skin cancer risk in an Asian population. Methods By using Taiwan’s National Health Insurance Research Database (NHIRD), we conducted three separate case–control studies of lip cancer, non-lip non-melanoma skin cancer and melanoma. Cases (n = 29,082) with a first-ever skin cancer diagnoses (2008–2015) were matched 1:10 to population controls. We estimated odds ratios (ORs) associating hydrochlorothiazide use with skin cancer risk by using conditional logistic regression. Results Hydrochlorothiazide use showed no overall association with any of the three outcomes: ORs for high cumulative use of HCTZ (≥50,000 mg) were 0.86 (95% CI 0.09–7.81) for lip cancer, 1.16 (95% CI 0.98–1.37) for non-lip NMSC and 1.07 (95% CI 0.65–1.76) for melanoma. There was some evidence of a dose–response pattern for non-lip NMSC, with an OR of 1.66 (95% CI 0.82–3.33) for 100,000–149,999 mg of HCTZ. The null findings were robust across subgroup and sensitivity analyses. Conclusion Use of HCTZ appears safe in terms of skin cancer risk in an Asian population.


2002 ◽  
Vol 147 (5) ◽  
pp. 950-956 ◽  
Author(s):  
H.M. Ramsay ◽  
A.A. Fryer ◽  
C.M. Hawley ◽  
A.G. Smith ◽  
D.L. Nicol ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 8 (43) ◽  
pp. 75411-75417 ◽  
Author(s):  
Keming Yang ◽  
Andrew Marley ◽  
Huilin Tang ◽  
Yiqing Song ◽  
Jean Y. Tang ◽  
...  

2017 ◽  
Vol 11 (suppl_1) ◽  
pp. S433-S434
Author(s):  
Y. Wu ◽  
S. Ghaly ◽  
S. Kerr ◽  
K. Krishnaprasad ◽  
R. Prosser ◽  
...  

2015 ◽  
Vol 9 (5) ◽  
pp. 2425-2429 ◽  
Author(s):  
JINGHUA FAN ◽  
YUHUA FAN ◽  
XIAOXIAO KANG ◽  
LIMIN ZHAO

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