The Impact of Aneurysmal Subarachnoid Hemorrhage on Blood Brain Barrier Permeability: What We Learnt?

2021 ◽  
Vol 69 (3) ◽  
pp. 753
Author(s):  
Alok Singh ◽  
BMahesh Kumar ◽  
Dhyuti Gupta
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Blood Brain Barrier ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
The Impact

Early CT perfusion changes and blood–brain barrier permeability after aneurysmal subarachnoid hemorrhage

2015 ◽  
Vol 57 (8) ◽  
pp. 767-773 ◽  
Author(s):  
Amanda Murphy ◽  
Airton Leonardo de Oliveira Manoel ◽  
Kyle Burgers ◽  
Ekaterina Kouzmina ◽  
Ting Lee ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Blood Brain Barrier ◽  
Ct Perfusion ◽  
Aneurysmal Subarachnoid Hemorrhage ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability

Blood-Brain Barrier Permeability Changes after Experimental Subarachnoid Hemorrhage

Neurosurgery ◽  
1992 ◽  
Vol 30 (6) ◽  
pp. 882-886 ◽  
Author(s):  
Antonino Germanó ◽  
Domenico dʼAvella ◽  
Rocco Cicciarello ◽  
Ronald L. Hayes ◽  
Francesco Tomasello
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Permeability Changes ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
Experimental Subarachnoid Hemorrhage

scholarly journals Effects of Neonatal Systemic Inflammation on Blood-Brain Barrier Permeability and Behaviour in Juvenile and Adult Rats

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
H. B. Stolp ◽  
P. A. Johansson ◽  
M. D. Habgood ◽  
K. M. Dziegielewska ◽  
N. R. Saunders ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Systemic Inflammation ◽  
Brain Barrier ◽  
Adult Rats ◽  
Dark Light ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
The Impact

Several neurological disorders have been linked to inflammatory insults suffered during development. We investigated the effects of neonatal systemic inflammation, induced by LPS injections, on blood-brain barrier permeability, endothelial tight junctions and behaviour of juvenile (P20) and adult rats. LPS-treatment resulted in altered cellular localisation of claudin-5 and changes in ultrastructural morphology of a few cerebral blood vessels. Barrier permeability to sucrose was significantly increased in LPS treated animals when adult but not at P20 or earlier. Behavioural tests showed that LPS treated animals at P20 exhibited altered behaviour using prepulse inhibition (PPI) analysis, whereas adults demonstrated altered behaviour in the dark/light test. These data indicate that an inflammatory insult during brain development can change blood-brain barrier permeability and behaviour in later life. It also suggests that the impact of inflammation can occur in several phases (short- and long-term) and that each phase might lead to different behavioural modifications.

Blood-Brain Barrier Permeability Changes after Experimental Subarachnoid Hemorrhage

Neurosurgery ◽  
1992 ◽  
Vol 30 (6) ◽  
pp. 882-886
Author(s):  
Antonino Germanó ◽  
Domenico d'Avella ◽  
Rocco Cicciarello ◽  
Ronald L. Hayes ◽  
Francesco Tomasello
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Barrier Permeability ◽  
Blood Brain Barrier Permeability ◽  
Permeability Changes ◽  
Blood Brain ◽  
Brain Barrier Permeability ◽  
Experimental Subarachnoid Hemorrhage
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