A comparison of a continuous noninvasive arterial pressure (CNAP™) monitor with an invasive arterial blood pressure monitor in the cardiac surgical ICU

The Finapres (Ohmeda, Madison, U.S.A.) is a non-invasive device which continuously measures the arterial blood pressure in a finger and produces a real-time display of the arterial pressure wave. It consists of a finger cuff with an infra-red transmission plethysmograph, a servo control box and a monitor unit. The device was compared with intra-arterial pressure monitoring in twenty patients during induction of anaesthesia for elective neurosurgical procedures. The differences between the two methods were considerable, ranging from −40 mmHg to +26 mmHg for mean pressure. While the Finapres has potential as a non-invasive continuous blood pressure monitor, the current model Finapres, as supplied, displays too great a variability for it to be used as an alternative to intra-arterial pressure monitoring.

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Validation of a tonometric noninvasive arterial blood pressure monitor in the intensive care setting

Anaesthesia ◽

10.1046/j.1365-2044.2003.03122.x ◽

2003 ◽

Vol 58 (5) ◽

pp. 448-454 ◽

Cited By ~ 14

Author(s):

L. A. Steiner ◽

A. J. Johnston ◽

R. Salvador ◽

M. Czosnyka ◽

D. K. Menon

Keyword(s):

Blood Pressure ◽

Intensive Care ◽

Arterial Blood Pressure ◽

Care Setting ◽

Intensive Care Setting ◽

Blood Pressure Monitor ◽

Pressure Monitor ◽

Arterial Blood

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Clinical evaluation of the Accutracker II ambulatory blood pressure monitor: assessment of performance in two countries and comparison with sphygmomanometry and intra-arterial blood pressure at rest and during exercise

Journal of Hypertension ◽

10.1097/00004872-198912000-00007 ◽

1989 ◽

Vol 7 (12) ◽

pp. 967-975 ◽

Cited By ~ 63

Author(s):

William B. White ◽

Per Lund-Johansen ◽

Ellen J. McCabe ◽

Per Omvik

Keyword(s):

Blood Pressure ◽

Arterial Blood Pressure ◽

Clinical Evaluation ◽

Ambulatory Blood Pressure ◽

Blood Pressure Monitor ◽

Pressure Monitor ◽

Assessment Of Performance ◽

Arterial Blood ◽

Ambulatory Blood Pressure Monitor

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Effects of Neuroactive Amino Acids Derivatives on Cardiac and Cerebral Mitochondria and Endothelial functions in Animals Exposed to Stress

Journal of Clinical and Health Sciences ◽

10.24191/jchs.v2i2.5885 ◽

2017 ◽

Vol 2 (2) ◽

pp. 34

Author(s):

TA Popova ◽

II Prokofiev ◽

IS Mokrousov ◽

Valentina Perfilova ◽

AV Borisov ◽

...

Keyword(s):

Nitric Oxide ◽

Blood Pressure ◽

Platelet Aggregation ◽

Atp Synthesis ◽

Elevated Concentration ◽

Blood Pressure Monitor ◽

Pressure Monitor ◽

Griess Reagent ◽

Arterial Blood ◽

Endothelial Functions

Introduction: To study the effects of glufimet, a new derivative of glutamic acid, and phenibut, a derivative of γ-aminobutyric acid (GABA), on cardiac and cerebral mitochondria and endothelial functions in animals following exposure to stress and inducible nitric oxide synthase (iNOS) inhibition. Methods: Rats suspended by their dorsal cervical skin fold for 24 hours served as the immobilization and pain stress model. Arterial blood pressure was determined using a non-invasive blood pressure monitor. Mitochondrial fraction of heart and brain homogenates were isolated by differential centrifugation and analysed for mitochondrial respiration intensity, lipid peroxidation (LPO) and antioxidant enzyme activity using polarographic method. The concentrations of nitric oxide (NO) terminal metabolites were measured using Griess reagent. Hemostasis indices were evaluated. Platelet aggregation was estimated using modified version of the Born method described by Gabbasov et al., 1989. Results: The present study demonstrated that stress leads to an elevated concentration of NO terminal metabolites and LPO products, decreased activity of antioxidant enzymes, reduced mitochondrial respiratory function, and endothelial dysfunction. Inhibition of iNOS by aminoguanidine had a protective effect. Phenibut and glufimet inhibited a rise in stress-induced nitric oxide production. This resulted in enhanced coupling of substrate peroxidation and ATP synthesis. The reduced LPO processes caused by glufimet and phenibut normalized the endothelial function which was proved by the absence of average daily blood pressure (BP) elevation episodes and a significant increase in platelet aggregation level. Conclusion: Glufimet and phenibut restrict the harmful effects of stress on the heart and brain possibly by modulating iNOS activity.

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