scholarly journals The dual role of necrostatin-1 in Parkinson’s disease models

2021 ◽  
Vol 16 (10) ◽  
pp. 2019
Author(s):  
JoséM Fuentes ◽  
SokhnaM. S. Yakhine-Diop ◽  
Eva Alegre-Cortes ◽  
Guadalupe Martínez-Chacón
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dual Role ◽  
Disease Models

Dual Role of Nitric Oxide in the Pathogenesis of Parkinson's Disease

2014 ◽  
Vol 1 (4) ◽  
pp. 243-253 ◽  
Author(s):  
Vaibhav Walia ◽  
Anuradha Sharma ◽  
Monika Gahlawat ◽  
O. P. Dube
Keyword(s):  
Nitric Oxide ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dual Role

Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways

2012 ◽  
Vol 45 (3) ◽  
pp. 1018-1030 ◽  
Author(s):  
Lilach Soreq ◽  
Yoram Ben-Shaul ◽  
Zvi Israel ◽  
Hagai Bergman ◽  
Hermona Soreq
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Meta Analysis ◽  
Disease Models

A fluorogenic probe based on chelation–hydrolysis-enhancement mechanism for visualizing Zn2+ in Parkinson's disease models

2019 ◽  
Vol 7 (14) ◽  
pp. 2252-2260 ◽  
Author(s):  
Gaobin Zhang ◽  
Yanfei Zhao ◽  
Bo Peng ◽  
Zheng Li ◽  
Chenchen Xu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Real Time ◽  
Biological Systems ◽  
Disease Models ◽  
Enhancement Mechanism ◽  
Fluorogenic Probe ◽  
Real Time Detection ◽  
Role Of Zn

Developing efficient methods for real-time detection of Zn2+ level in biological systems is highly relevant to improve our understanding of the role of Zn2+ in the progression of Parkinson's disease (PD).

A proposed dual role of neuromelanin in the pathogenesis of Parkinson's disease

Neurology ◽  
2006 ◽  
Vol 67 (Issue 7, Supplement 2) ◽  
pp. S8-S11 ◽  
Author(s):  
L. Zecca ◽  
F. A. Zucca ◽  
A. Albertini ◽  
E. Rizzio ◽  
R. G. Fariello
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Dual Role

Neuroprotective effects of nitidine in Parkinson's disease models through inhibiting microglia activation: role of the Jak2–Stat3 pathway

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 71328-71337 ◽  
Author(s):  
Bao Wang ◽  
Xing-qin Wang ◽  
Shao-song Yang ◽  
Xi Liu ◽  
Da-yun Feng ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Animal Models ◽  
Microglial Activation ◽  
Microglia Activation ◽  
Disease Models ◽  
Neuroprotective Effects ◽  
Stat3 Pathway ◽  
Behavioural Function

In this work we found that nitidine could significantly suppress microglial activationviathe Jak2–Stat3 pathway and obviously improve behavioural function in Parkinson's disease (PD) animal models, which sheds light on PD treatment.

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