scholarly journals Arthroscopic synovial biopsy in definitive diagnosis of joint diseases: An evaluation of efficacy and precision

2012 ◽  
Vol 2 (2) ◽  
pp. 102 ◽  
Author(s):  
Onis Singhal ◽  
Viplesh Kaur ◽  
ManishKumar Singhal ◽  
YV Machave ◽  
Anshu Gupta ◽  
...  
Keyword(s):  
Definitive Diagnosis ◽  
Synovial Biopsy ◽  
Joint Diseases

scholarly journals ROLE OF NEEDLE SYNOVIAL BIOPSY IN JOINT DISEASES

2015 ◽  
Vol 4 (44) ◽  
pp. 7626-7634 ◽  
Author(s):  
Venkataraman M ◽  
Sathyadharan P
Keyword(s):  
Synovial Biopsy ◽  
Joint Diseases

scholarly journals Synovial Biopsy in Joint Diseases: A Morphological Study

2019 ◽  
Vol 8 (6) ◽  
pp. 715-724
Author(s):  
J Sheeja ◽  
◽  
N Sangeetha ◽  
V Aruna Padmavathi ◽  
S Saranyabai ◽  
...  
Keyword(s):  
Morphological Study ◽  
Synovial Biopsy ◽  
Joint Diseases

scholarly journals Study of histomorphological features of synovial biopsy in joint diseases

2019 ◽  
Vol 6 (4) ◽  
pp. 636-641
Author(s):  
Gopinath Rajesh ◽  
◽  
Shwetha Patil ◽  
N Ranganath ◽  
◽  
...  
Keyword(s):  
Synovial Biopsy ◽  
Joint Diseases

scholarly journals A prospective study for diagnosing joint diseases by synovial fluid analysis and percutaneous needle biopsy of synovium

2017 ◽  
Vol 3 (4) ◽  
pp. 661
Author(s):  
Ganesh Kumar Reddy Mundla ◽  
Ramprasad Rallapalli ◽  
Sunil Santosh Galla ◽  
Biju Ravindran
Keyword(s):  
Synovial Fluid ◽  
Needle Biopsy ◽  
Synovial Biopsy ◽  
Joint Involvement ◽  
Joint Diseases ◽  
Diagnostic Aid ◽  
Fluid Analysis ◽  
Synovial Fluid Analysis ◽  
Aetiological Diagnosis ◽  
A Prospective Study

<p><strong>Background:</strong> Arthritis is an important cause of morbidity, presenting as monoarticular or polyarticular lesion. Percutaneous synovial aspiration and biopsy can help in identifying specific aetiological diagnosis. The study was conducted with the objective to evaluate the efficacy of percutaneous synovial biopsy as a diagnostic aid and study the characteristics of synovial fluid in various joint diseases.</p><p><strong>Methods:</strong> Percutaneous synovial biopsy along with synovial fluid analysis was studied in all the 100 enrolled cases arthritis. The fluid was subjected to physical, biochemical, and cytological analysis.</p><p><strong>Results:</strong> Of the 100 cases, monoarticular joint involvement predominated over polyarticular (n = 80; 80%), knee joint (60%) was most commonly affected in  monoarticular and polyarticular  arthrthritis. Rheumatoid arthritis (RA) (n=33; 33%)is the most common aetiology followed by tuberculosis (n=22). Males predominated over females in this study (n = 61; 61%).</p><p><strong>Conclusion:</strong> The evaluation of synovial fluid and synovial biopsy in joint diseases will stimulate its use as routine investigative procedure in the diagnosis of various puzzling joint disorders. Both these procedures can be done simultaneously trough the same site of aspiration by the same needle.</p>

Ultrastructural investigation of an adenoma of the pituitary post mortem

1987 ◽  
Vol 45 ◽  
pp. 622-623
Author(s):  
Shirley Siew ◽  
W. C. deMendonca
Keyword(s):  
Deleterious Effect ◽  
Anterior Lobe ◽  
Definitive Diagnosis ◽  
Pars Intermedia ◽  
Post Mortem ◽  
Close Apposition ◽  
Autopsy Material ◽  
Progressive Loss ◽  
Transmission Electron ◽  
Means Of Transmission

The deleterious effect of post mortem degeneration results in a progressive loss of ultrastructural detail. This had led to reluctance (if not refusal) to examine autopsy material by means of transmission electron microscopy. Nevertheless, Johannesen has drawn attention to the fact that a sufficient amount of significant features may be preserved in order to enable the establishment of a definitive diagnosis, even on “graveyard” tissue.Routine histopathology of the autopsy organs of a woman of 78 showed the presence of a well circumscribed adenoma in the anterior lobe of the pituitary. The lesion came into close apposition to the pars intermedia. Its architecture was more compact and less vascular than that of the anterior lobe. However, there was some grouping of the cells in relation to blood vessels. The cells tended to be smaller, with a higher nucleocytoplasmic ratio. The cytoplasm showed a paucity of granules. In some of the cells, it was eosinophilic.

Serpiginous Granuloma Annulare: A Case Report

2018 ◽  
Vol 3 (02) ◽  
Author(s):  
Rajni Sharma ◽  
Sujaya Manvi
Keyword(s):  
Skin Condition ◽  
Positive Tuberculin Skin Test ◽  
Definitive Diagnosis ◽  
Granuloma Annulare ◽  
Unknown Etiology ◽  
Thyroid Disorders ◽  
Precipitating Factors ◽  
Immunological Mechanism ◽  
Physical Trauma ◽  
Insect Bites

Granuloma annulare (GA) is a benign inflammatory skin condition of unknown etiology. Various clinical forms of GA including localized, generalized, subcutaneous, patch and perforating types, have been described. Although the etiology and pathogenesis of granuloma annulare are obscure, there is much evidence for an immunological mechanism. Precipitating factors are insect bites, sunburn, photochemotherapy, drugs, physical trauma, acute phlebitis and sepsis after surgery.[1] Some authors have proposed that it might be associated with a variety of underlying conditions such as thyroid disorders, diabetes mellitus and positive tuberculin skin test.[2] For definitive diagnosis, a biopsy should be performed. We report a case of generalized GA with serpiginous borders on the dorsal aspects of the hands and arms along with an association with diabetes.

The Invisible Evil Twin of an Adrenal Adenoma

2019 ◽  
Vol 4 (1) ◽  
pp. 58
Author(s):  
Aimi Fadilah Mohamad ◽  
Fatimah Zaherah Mohamed Shah ◽  
Nur Aisyah Zainordin ◽  
Ur 'Aini Eddy Warman ◽  
Nazimah Ab Mumin ◽  
...  
Keyword(s):  
Adrenal Glands ◽  
Adrenal Adenoma ◽  
Definitive Diagnosis ◽  
Dynamic Tests ◽  
Venous Sampling ◽  
Aldosterone Secretion ◽  
Aldosterone Level ◽  
Suppression Test ◽  
The Right ◽  
Secondary Causes

Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal adenoma. It can be cured with surgical resection of the aldosterone-secreting adenoma leading to resolution of hypertension, hypokalemia and increased cardiovascular risk associated with hyperaldosteronism. We present a case of a man with previous ischemic heart disease (IHD) who presented with resistant hypertension. Investigations for secondary causes of hypertension revealed an elevated aldosterone level and saline suppression test confirmed the diagnosis of PA. Radiological examination revealed a left adrenal adenoma and a normal right adrenal gland. However, adrenal venous sampling showed lateralization of aldosterone secretion towards the right. He subsequently underwent a laparoscopic right adrenalectomy which improved his BP control promptly. This case highlights the importance of recognizing the need to investigate for secondary causes of hypertension. It also underscores the importance of dynamic tests, which may not be easily accessible to most clinicians but should pursue, to allow a definitive diagnosis and effective treatment.

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