scholarly journals The Efficacy of Augment of D-Cycloserine and Cognitive-behavioral Therapy on Adolescent with one Type of Anxiety Disorders: A Double-blind Randomized Controlled Trial

2017 ◽  
Vol 6 (1) ◽  
pp. 11 ◽  
Author(s):  
Ali Soheilimehr ◽  
Soroor Arman ◽  
MohammadReza Maracy
2012 ◽  
Vol 20 (8) ◽  
pp. 707-716 ◽  
Author(s):  
Gretchen A. Brenes ◽  
Michael E. Miller ◽  
Jeff D. Williamson ◽  
W. Vaughn McCall ◽  
Mark Knudson ◽  
...  

2021 ◽  
Author(s):  
Arka Ghosh ◽  
Rithwik Cherian ◽  
Surbhit Wagle ◽  
Parth Sharma ◽  
Karthikeyan R. Kannan ◽  
...  

Most individuals vulnerable to depression do not receive adequate or timely treatment globally. Unguided computerized cognitive behavioral therapy (cCBT) has the potential to bridge this treatment gap. However, the real-world effectiveness of unguided cCBT interventions, particularly in low- and middle-income countries (LMICs), remains inconclusive. In this study, we report the design and development of a new unguided cCBT intervention, TreadWill, and its pragmatic evaluation. TreadWill was designed to be fully automated, engaging, easy to use, and accessible in LMICs. To evaluate its effectiveness and engagement level, we performed a double-blind, fully-remote, randomized controlled trial with 598 participants in India. The use of TreadWill significantly reduced depression-related and anxiety-related symptoms. Compared with a plain-text version with the same therapeutic content, the full-featured version of TreadWill showed significantly higher engagement. Overall, our study provides a new resource and evidence for the use of unguided cCBT as a scalable intervention in LMICs.


2019 ◽  
Vol 87 (6) ◽  
pp. 521-529 ◽  
Author(s):  
Margo de Jonge ◽  
Claudi L. H. Bockting ◽  
Martijn J. Kikkert ◽  
Maarten K. van Dijk ◽  
Digna J. F. van Schaik ◽  
...  

2020 ◽  
Vol 88 (9) ◽  
pp. 818-828
Author(s):  
Pauline D. Janse ◽  
Kim de Jong ◽  
Carola Veerkamp ◽  
Maarten K. van Dijk ◽  
Giel J. M. Hutschemaekers ◽  
...  

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