Xanthogranulomatous pyelonephritis: Rare presentation of a rare disease

AbstractXanthogranulomatous pyelonephritis is a rare chronic renal infection of unknown pathogenesis characterized by replacement of renal parenchyma by lipid filled macrophages frequently associated with an enlarged, non-functioning kidney and an obstructing calculus. We report a case of a 45 year old non diabetic female who presented with gradually enlarging renal mass with extensive retroperitoneal involvement and a non-functioning kidney with no evidence of obstructing stone or fat density and simulating malignancy. She was diagnosed as stage III Xanthogranulomatous pyelonephritis and managed with radical nephrectomy with favourable outcome.

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Metastasis in mixed epithelial stromal tumour of the kidney: a rare presentation

BMJ Case Reports ◽

10.1136/bcr-2019-229293 ◽

2019 ◽

Vol 12 (9) ◽

pp. e229293

Author(s):

Pravin Sambhaji Holkar ◽

Tarun Jain ◽

Vikas Kavishwar ◽

Jayashri Sanjay Pandya

Keyword(s):

Positron Emission Tomography ◽

Female Patient ◽

Radical Nephrectomy ◽

Renal Mass ◽

Nodal Metastasis ◽

Stromal Tumour ◽

Emission Tomography ◽

Rare Presentation ◽

Positron Emission ◽

Perimenopausal Women

Mixed epithelial stromal tumour of the kidney (MESTK) is a rare genitourinary tract tumour. MESTK is typically seen in perimenopausal women and rarely reported in men and children. MESTK has been included in the WHO renal tumour classification since 2004. Here, we present a case of 50-year-old female patient who underwent left radical nephrectomy for left renal mass. Postoperative positron emission tomography (PET) scan also showed nodal metastasis, for which, she was started on chemotherapy.

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Xanthogranulomatous Pyelonephritis Associated with Hepatic Dysfunction in Pregnancy

Case Reports in Obstetrics and Gynecology ◽

10.1155/2015/936262 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4

Author(s):

L. Ferreira ◽

C. Oliveira ◽

C. Cruz ◽

A. Pacheco

Keyword(s):

Pregnant Woman ◽

Rare Disease ◽

Hepatic Dysfunction ◽

Rare Event ◽

Renal Parenchyma ◽

Xanthogranulomatous Pyelonephritis ◽

Normal Renal Parenchyma ◽

Foamy Macrophages ◽

In Pregnancy ◽

Total Nephrectomy

Xanthogranulomatous pyelonephritis is a rare disease characterised by the replacement of normal renal parenchyma by foamy macrophages. The only treatment for this type of pyelonephritis is of a surgical nature with partial or total nephrectomy. The occurrence of xanthogranulomatous pyelonephritis during pregnancy is a rare event (with only 6 cases described in the literature). We report a case of xanthogranulomatous pyelonephritis in a 32-week pregnant woman associated with hepatic dysfunction.

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Rare squamous cell carcinoma of the kidney with concurrent xanthogranulomatous pyelonephritis: A case report and review of the literature

Open Medicine ◽

10.1515/med-2020-0233 ◽

2021 ◽

Vol 16 (1) ◽

pp. 128-133

Author(s):

Tsung-Hsin Chang ◽

Jen-Shu Tseng

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Radical Nephrectomy ◽

Medical Literature ◽

Xanthogranulomatous Pyelonephritis ◽

Rare Presentation ◽

English Medical Literature ◽

History Of ◽

The Right

Abstract Case presentation In the current study, we report a 69-year-old female patient who was initially diagnosed with xanthogranulomatous pyelonephritis (XGPN) with nephrolithiasis and a peri-renal abscess. She presented to our department with right flank pain. Physical examination revealed right costovertebral angle knocking pain and computed tomography revealed dilated calyces and one staghorn stone over right kidney, with multiple abscess accumulations over the right peri-renal region. Right radical nephrectomy was performed using a transperitoneal flank approach, and pathology revealed squamous cell carcinoma (SCC) with concurrent XGPN. The patient was alive at 4 months post-operative follow-up. To the best of our knowledge, this is only the fifth case of renal SCC with concurrent XGPN reported in the English medical literature. Conclusion Renal SCC with coexisting XGPN is an extremely rare presentation and only four cases have been previously reported in the English medical literature. A positive diagnosis for this rare combination of diseases was established, based on pathological and immunohistochemical examinations after radical nephrectomy. Poor prognosis has been reported in such cases. Malignancies should be considered in patients with a long-standing history of urolithiasis.

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