Comparative study of the efficacy of lycopene and aloe vera in the treatment of oral submucous fibrosis

2015 ◽  
Vol 4 (1) ◽  
pp. 13 ◽  
Author(s):  
Santosh Patil ◽  
Rohit Sahu ◽  
MG Sghaireen ◽  
SomnathReddy Kunsi ◽  
Sneha Maheshwari
Keyword(s):  
Comparative Study ◽  
Oral Submucous Fibrosis ◽  
Aloe Vera ◽  
Submucous Fibrosis

scholarly journals EFFICACY OF ANTIOXIDANT WITH ALOE VERA GEL VERSUS INTRA-LESIONAL STEROIDS IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS - A PROSPECTIVE COMPARATIVE STUDY

2021 ◽  
Vol 71 (Suppl-3) ◽  
pp. S526-29
Author(s):  
Muhammad Tahir ◽  
Asim Abbas ◽  
Faiz Ul Hassan Nawaz ◽  
Mohsin Raza ◽  
Atif Rafique ◽  
...  
Keyword(s):  
Comparative Study ◽  
Lipoic Acid ◽  
Oral Submucous Fibrosis ◽  
Aloe Vera ◽  
Mouth Opening ◽  
Burning Sensation ◽  
Alpha Lipoic Acid ◽  
Aloe Vera Gel ◽  
Prospective Comparative Study ◽  
Submucous Fibrosis

Objective: To compared efficacy of alpha lipoic acid (antioxidant medication) and aloe vera gel together versus intralesional steroids (hydrocortisone) in management of oral submucous fibrosis by evaluating post treatment clinical features of mouth opening and burning sensation. Study Design: A prospective comparative study. Place and Duration of Study: Department of ENT, Combined Military Hospital, Malir Karachi, from Jul 2018 to Mar 2020. Methodology: Twenty-eight patients were involved in the research and were distributed into two groups, I and II. Alpha lipoid acid with aloe vera gel was given in group I and hydrocortisone was given in group II. Burning sensation and mouth opening were recorded both at start and at monthly interval later on for three consecutive months. The data collected were statistically analyzed by using SPSS-22. Results: A significant lessening in burning sensation (p<0.001) and improvement in mouth opening were noticed in both groups. However, comparison between alpha lipoic acid with aloe vera gel group versus hydrocortisone group showed almost similar results. Conclusion: Alpha lipoic acid and aloe vera gel can significantly improve oral submucous fibrosis clinically. So, these can be utilized as an alternative option in cases where intralesional steroid is poorly tolerated or is contraindicated.

Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis

2013 ◽  
Vol 116 (6) ◽  
pp. 717-724 ◽  
Author(s):  
Sarwar Alam ◽  
Iqbal Ali ◽  
K.Y. Giri ◽  
S. Gokkulakrishnan ◽  
Subodh S. Natu ◽  
...  
Keyword(s):  
Adjuvant Treatment ◽  
Oral Submucous Fibrosis ◽  
Aloe Vera ◽  
Aloe Vera Gel ◽  
Submucous Fibrosis

scholarly journals A comparative study to evaluate the efficacy of lycopene and curcumin in oral submucous fibrosis patients: A randomized clinical trial

2018 ◽  
Vol 29 (3) ◽  
pp. 303 ◽  
Author(s):  
Gargi Saran ◽  
Deepak Umapathy ◽  
Neeta Misra ◽  
ShivakumarGaniga Channaiah ◽  
Priya Singh ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Comparative Study ◽  
Randomized Clinical Trial ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals Aloe vera in the management of oral submucous fibrosis

2017 ◽  
Vol 04 ◽  
pp. 1
Author(s):  
Vagish Kumar L Shanbhag ◽  
◽  
Keyword(s):  
Sri Lanka ◽  
Oral Submucous Fibrosis ◽  
Aloe Vera ◽  
Mouth Opening ◽  
Malignant Potential ◽  
Progressive Reduction ◽  
Submucous Fibrosis ◽  
Current Article ◽  
Malignant Condition

Oral submucous fibrosis is a pre-malignant condition commonly prevalent in India, Pakistan, Taiwan and Sri Lanka. Patients characteristically exhibit progressive reduction in mouth opening. The disease has a high malignant potential and thus should be diagnosed and treated at the earliest. However, none of the currently used medical therapies show promising results. The current article briefly reviews the role of Aloe vera in the management of oral submucous fibrosis.

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