aloe vera
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2023 ◽  
Vol 83 ◽  
L. R. Zago ◽  
K. Prado ◽  
V. L. Benedito ◽  
M. M. Pereira

Abstract Alo vera is a centenary remedy use for minor wounds and burns, but its mechanism of wound healing has not been know since. This article will evaluate and gather evidence of the effectiveness and safety of the use of aloe vera in the treatment of burns. A systematic review was carried out on the databases: MEDLINE, LILACS, DECS, SCIELO, in the last 7 years, with the descriptors: “Aloe”, “Burns” and “treatment”. 16 articles were found. After using the exclusion criteria; research in non-humans and literature review; 5 articles were selected. The article Teplick et al. (2018) performed an in vitro clinical experiment in A. Vera solution, and demonstrated that there was proliferation and cell migration of human skin fibroblasts and keratinocytes, in addition to being protective in the death of keratonocytes. That is, it accelerates the healing of wounds. Muangman et al. (2016), evaluated 50 patients with 20% of the total body surface area burned with second-degree burns, between 18-60 years old, with half of the group receiving gauze dressings with soft paraffin containing 0.5% chlorhexidine acetate and the other half receiving polyester dressings containing extracts of medicinal plants mainly Aloe Vera. It had positive results, a higher healing speed and shorter hospital stay compared to the control group. Hwang et al. (2015) investigated the antioxidant effects of different extracts from 2,4,6,8,12 months of Aloe Vera. And the 6-month concentrated extract of 0.25 mg / mL had a higher content of flavonoids (9.750 mg catechin equivalent / g extract) and polyphenols (23.375 mg gallic acid equivalent / g extract) and the greater ferric reducing antioxidant power (0.047 mM equivalent ferrous sulfate / mg extract), that is, greater potential for free radical scavenging and also a protective effect against oxidative stress induced by tert-butyl hydroperoxide (t-BHP), suggesting evidence of a bioactive potential of A. vera . However, in the article Kolacz et al. (2014) suggested as an alternative treatment the use of Aloe Vera dressing in combination with honey, lanolin, olive oil, wheat germ oil, marshmallow root, wormwood, comfrey root, white oak bark, lobelia inflata, glycerin vegetable oil, beeswax and myrrh, without obtaining significant and conclusive results that would allow the conventional treatment of burns to be subsidized. Finally, in the article by Zurita and Gallegos (2017), it carried out a descriptive cross-sectional study with 321 people, both sexes between 17-76 years of age, of an inductive nature, exploring the experience of this population and their behavioral attitudes regarding the treatment of dermatoses. Aloe vera had 13.8% cited by individuals in the treatment of acne and 33.6% in the treatment of burns. Even with evidence that suggests the efficacy in the treatment of burns with the use of Aloe Vera extract, further clinical trials with larger sample space on the use of Aloe vera dressings in medium burns are suggested for further conclusions.

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Chirato Godana Korra

Purpose This paper aims to prevent cotton textiles from fungi damage using eco-friendly aloe vera leaf extract, which was applied at a minimum amount, and cost-effective material. Design/methodology/approach Batch extraction method using methanol solvent; phytochemical analysis was investigated and three-level factorial design of experiment and analysis of variance (ANOVA) was used for the optimization of 27 test runs. The finish was applied by pad-dry-cue at distinct concentrations, and the chemical property after treatment was studied. Colorfastness and coordinates are analyzed. Cotton fabrics were cultured with Fusarium oxysporum fungi and the anti-fungal property was examined and reported according to AATCC 30–2004 standard. Findings The maximum yield of extract was at an optimum volume of 200 ml, 65 °C for 120 min. The effective antifungal fabric was achieved with minimum concentrations. There was significant strength loss in warp and weft direction. The treatment results in yellow-colored cotton fabric with fastness grade 3. The antifungal effect is durable until fifteen washes as the tensile strength losses were less than 1%. Research limitations/implications The findings of this work were based on samples considered in the laboratory. However, it can be reproducible at the factory production scale the treatment has the potential of yielding yellow dyed cotton fabric with multifunctional finishing. Practical implications The treated fabric is against Fusarium oxysporum Fungi which is one of the vital antimicrobial properties of textile apparel products for various areas of application. Social implications The natural extract material applied to a textile material is eco-friendly effective against microbes of cotton seeds during cultivation and apparel end-uses. Originality/value The work application of fungi resistance on cotton fabric using aloe vera active component was original; this work provides extraction of the active agent from aloe vera leaf, which is optimized statically and successfully applied for anti-fungal activity on cotton fabric.

2022 ◽  
Vol 22 (1) ◽  
Florence Nalimu ◽  
Joseph Oloro ◽  
Emanuel L. Peter ◽  
Patrick Engeu Ogwang

Abstract Background Several local communities in Central, Western, Eastern, and Northern regions of Uganda have been using the whole leaf extracts of Aloe vera (L.) Burm. f. (Asphodelaceae) in the treatment of various ailments. Also, several commercial companies sell A. vera as soft drinks in Uganda. However, there are inadequate reports on the toxicities of such preparations. This paper reports the acute and sub-acute oral toxicity of aqueous extracts of whole leaf and green rind of A. vera in Wistar rats. Methods Acute oral toxicity test was carried out in female Wistar rats at doses of 175, 550, 1750, and 5000 mg/kg, p.o. The animals were observed for signs of toxicity for 14 days. Similarly, a sub-acute oral toxicity test was performed in both sexes of rats at doses of 200, 400, and 800 mg/kg, p.o. daily for 28 days. All the groups of animals were monitored for behavioral, morphological, biochemical, and physiological changes, including mortality and compared with respective controls. Body weights were measured weekly while the animals’ relative organ weights, hematological, biochemical, gross, and microscopic pathology were examined on day 29. Results There was no mortality or apparent behavioral changes at the doses tested in acute and sub-acute oral toxicity tests. Thus, the Median Lethal Dose (LD50) of green rind and whole leaf aqueous extracts was above 5000 mg/kg. Gross anatomy revealed that the rats’ relative spleen weight in green rind extract at 200 mg/kg significantly decreased compared to the control group. The creatinine levels in female rats that received green rind extract and the chloride ion levels in male rats administered whole leaf extract were significantly elevated. Conversely, Mean Corpuscular Hemoglobin Concentration (MCHC) levels significantly decreased at lower doses of the green rind extract compared to the control. Histopathology of the kidney revealed the renal interstitium’s inflammation at doses of 200 and 800 mg/kg of the whole leaf extract. Conclusion The findings demonstrated that A. vera green rind and whole leaf extracts are non-toxic at relatively high doses when used for a short duration. Prolonged use of the aqueous whole leaf extract might be associated with kidney toxicity.

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 310
María Carolina Otálora ◽  
Andrea Wilches-Torres ◽  
Jovanny A. Gómez Castaño

In this work, the capacity of the mucilage extracted from the cladodes of Opuntia ficus-indica (OFI) and aloe vera (AV) leaves as wall material in the microencapsulation of pink guava carotenoids using spray-drying was studied. The stability of the encapsulated carotenoids was quantified using UV–vis and HPLC/MS techniques. Likewise, the antioxidant activity (TEAC), color (CIELab), structural (FTIR) and microstructural (SEM and particle size) properties, as well as the total dietary content, of both types of mucilage microcapsules were determined. Our results show that the use of AV mucilage, compared to OFI mucilage, increased both the retention of β-carotene and the antioxidant capacity of the carotenoid microcapsules by around 14%, as well as the total carotenoid content (TCC) by around 26%, and also favors the formation of spherical-type particles (Ø ≅ 26 µm) without the apparent damage of a more uniform size and with an attractive red-yellow hue. This type of microcapsules is proposed as a convenient alternative means to incorporate guava carotenoids, a natural colorant with a high antioxidant capacity, and dietary fiber content in the manufacture of functional products, which is a topic of interest for the food, pharmaceutical, and cosmetic industries.

Gels ◽  
2022 ◽  
Vol 8 (1) ◽  
pp. 42
Sadia Afzal ◽  
Muhammad Zahid ◽  
Zulfiqar Ahmad Rehan ◽  
H. M. Fayzan Shakir ◽  
Hamza Javed ◽  

Ultrasound imaging is a widely used technique in every health care center and hospital. Ultrasound gel is used as a coupling medium in all ultrasound procedures to replace air between the transducer and the patient’s skin, as ultrasound waves have trouble in traveling through air. This research was performed to formulate an inexpensive alternative to commercially available ultrasound gel as it is expensive and imported from other countries. Different formulations with different concentrations of carbopol 980 (CAR 980) and methylparaben were prepared with natural ingredients such as aloe vera gel and certain available chemicals that have no harmful effects on the skin. To justify the efficiency of the formulations; necessary physicochemical characteristics such as visual clarity, homogeneity, transparency, skin irritation, antibacterial activity, pH, stability, spreadability, conductivity, acoustic impedance, viscosity, and cost were evaluated. Moreover, a comparison study was also conducted with commercially available ultrasound gel that was utilized as a control. All samples showed excellent transparency and no microbial growth. S1 was the only formulation that met all of the requirements for commercial ultrasound gel and produced images that were similar to those produced by commercial ultrasound gel. So, this formulation could be used as an alternative to expensive commercial ultrasound gel for taking images in hospitals and medical centers.

2022 ◽  
Vol 1 (1) ◽  
pp. 200-206
Asman Sadino ◽  
Riza Apriani ◽  
Agustine Chandra Suryana ◽  
Arief Rakhmatuloh ◽  
Aning Suryani ◽  

ABSTRAKPandemi Covid-19 yang terjadi saat ini beberapa waktu yang lalu menyebabkan kelangkaan hand sanitizer dipasaran, hal ini membuat resah sebagian masyarakat. Pembuatan hand sanitizer yang dibuat dengan komposisi yang kurang tepat maka efektivitas hand sanitizer dalam membunuh bakteri dan virus tentunya akan berkurang. Pemanfaatan bahan alam sebagai bahan alternatif dalam pembuatan hand sanitizer. Diketahui  beberapa tanaman yang memiliki kemampuan daya hambat terhadap bakteri yang bisa digunakan sebagai zat aktif maupun zat tambahan di dalam produksi hand sanitizer salah satunya adalah lidah buaya. Tujuan dari kegiatan pengabdian ini adalah menghasilkan suatu produk kesehatan yang dapat dimanfaatkan baik untuk diri sendiri, keluarga dan masyarakat sekitar dalam rangka untuk mencegah penyebaran virus Covid-19. Metode yang digunakan dengan memberi penjelasan kegunaan dan keunggulan sediaan hand sanitizer yang terbuat dari bahan alami yaitu lidah buaya (Aloe vera) melalui video dan pamflet. Hasil dari kegiatan pengabdian kepada masyarakat ini dinilai dapat memberikan dampak positif kepada masyarakat Desa tambakbaya, Kecamatan Cisurupan, Kabupaten Garut dilihat dari antusiasme masyarakat Desa dalam menerima pamflet dan video sebagai sumber informasi yang sangat bermanfaat bagi mereka dalam membuat hand sanitizer berbahan dasar alami (Aloe vera) sehingga bisa dirasakan manfaatnya. Kerjasama antara kepala Desa dan aparatur Desa harus terus ditingkatkan agar dampak positif dapat menjadi dampak berkelanjutan. Kata Kunci: Hand sanitizer, antiseptik alami, aloe vera, pencegahan virus corona  ABSTRACTThe Covid-19 pandemic that occurred some time ago caused the scarcity of hand sanitizers in the market, this made some people nervous. Making hand sanitizers that are made with inappropriate compositions will reduce the effectiveness of hand sanitizers in killing bacteria and viruses. Utilization of natural materials as alternative materials in making hand sanitizers. It is known that several plants can inhibit bacteria which can be used as active substances or additives in the production of hand sanitizers, one of which is aloe vera. The purpose of this service activity is to produce a health product that can be used for both yourself, your family, and the surrounding community to prevent the spread of the Covid-19 virus. The method used is to explain the uses and advantages of hand sanitizer preparations made from natural ingredients, namely aloe vera (Aloe vera) through videos and pamphlets. The results of this community service activity are considered to have a positive impact on the people of Tambakbaya Village, Cisurupan District, Garut Regency, seen from the enthusiasm of the Village community in receiving pamphlets and videos as a source of information that is very useful for them in making hand sanitizers made from natural ingredients (Aloe vera) so that the benefits can be felt. Cooperation between the village head and village officials must be continuously improved so that positive impacts can become sustainable impacts. Keywords: Hand sanitizer, natural antiseptic, aloe vera, coronavirus prevention

2022 ◽  
pp. 179-187
Jean M. Bokelmann

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