scholarly journals Influence of Glyphaea brevis twig extract on nucleus, tight junctions and expression of inhibin-β, stem cell factor, and androgen binding protein in TM4 Sertoli cells

2019 ◽  
Vol 8 (4) ◽  
pp. 157
Author(s):  
JanetOlayemi Olugbodi ◽  
OluwafemiAdeleke Ojo ◽  
Oladipupo David ◽  
AfolabiClement Akinmoladun
1980 ◽  
Vol 85 (3) ◽  
pp. 443-448 ◽  
Author(s):  
S. CARREAU ◽  
M. A. DROSDOWSKY ◽  
C. PISSELET ◽  
M. COUROT

Androgen-binding protein (ABP) was measured in the testes of 50-day-old lambs. The animals were hypophysectomized and treatment lasting for 5 days was begun 15 days after surgery. In hypophysectomized but otherwise untreated lambs (control group), no 5α-dihydrotestosterone binding was detectable in testicular cytosol. One out of four lambs gave a positive response with FSH treatment (25 fmol ABP/mg protein), whereas a restoration of the synthesis of ABP was noted in all LH-treated animals (19 ± 9 (s.e.m.) fmol ABP/mg, n = 4). No synergism between the two gonadotrophins was observed in lambs treated simultaneously with FSH and LH (19 ± 4 fmol ABP/mg, n = 5). Testosterone treatment elicited a greater response (37 ± 9 fmol ABP/mg, n = 5) than FSH or LH alone and the response was not increased by the simultaneous addition of FSH (38 ± 10 fmol ABP/mg, n = 5). Whatever the treatment, no influence was observed either on the number of supporting cells (undifferentiated Sertoli cells) or the length of the seminiferous tubules (P > 0·05); the diameter of tubules was significantly increased in the group treated with FSH and LH. It is postulated that testosterone may have a direct effect on the production of ABP by the supporting cells of the impuberal lamb.


1980 ◽  
Vol 77 (9) ◽  
pp. 5322-5326 ◽  
Author(s):  
A. L. Kierszenbaum ◽  
M. Feldman ◽  
O. Lea ◽  
W. A. Spruill ◽  
L. L. Tres ◽  
...  

1982 ◽  
Vol 38 (3) ◽  
pp. 406-407 ◽  
Author(s):  
G. Citro ◽  
R. Zito ◽  
M. L. Marcante ◽  
M. Galdieri ◽  
A. Floridi ◽  
...  

2006 ◽  
Vol 101 (3) ◽  
pp. 334-339 ◽  
Author(s):  
XianZhi Xiong ◽  
AiGuo Wang ◽  
GuoHong Liu ◽  
HongKai Liu ◽  
Chong Wang ◽  
...  

Endocrinology ◽  
1986 ◽  
Vol 118 (1) ◽  
pp. 383-392 ◽  
Author(s):  
VIRGILIO PEREZ-INFANTE ◽  
C. WAYNE BARDIN ◽  
GLEN L. GUNSALUS ◽  
NEAL A. MUSTO ◽  
KATHRYN A. RICH ◽  
...  

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