The role of phantoms in magnetic resonance imaging-guided focused ultrasound surgery

2019 ◽  
Vol 5 (2) ◽  
pp. 52
Author(s):  
Christakis Damianou
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Resonance Imaging ◽  
Ultrasound Surgery ◽  
Focused Ultrasound Surgery

scholarly journals Transcranial Magnetic Resonance Imaging– Guided Focused Ultrasound Surgery of Brain Tumors

Neurosurgery ◽  
2010 ◽  
Vol 66 (2) ◽  
pp. 323-332 ◽  
Author(s):  
Nathan McDannold ◽  
Greg T. Clement ◽  
Peter Black ◽  
Ferenc Jolesz ◽  
Kullervo Hynynen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Resonance Imaging ◽  
Ultrasound Surgery ◽  
Temperature Imaging ◽  
Focused Ultrasound Surgery ◽  
Brain Surface ◽  
Magnetic Resonance Temperature Imaging ◽  
The Brain

Abstract OBJECTIVE This work evaluated the clinical feasibility of transcranial magnetic resonance imaging–guided focused ultrasound surgery. METHODS Transcranial magnetic resonance imaging–guided focused ultrasound surgery offers a potential noninvasive alternative to surgical resection. The method combines a hemispherical phased-array transducer and patient-specific treatment planning based on acoustic models with feedback control based on magnetic resonance temperature imaging to overcome the effects of the cranium and allow for controlled and precise thermal ablation in the brain. In initial trials in 3 glioblastoma patients, multiple focused ultrasound exposures were applied up to the maximum acoustic power available. Offline analysis of the magnetic resonance temperature images evaluated the temperature changes at the focus and brain surface. RESULTS We found that it was possible to focus an ultrasound beam transcranially into the brain and to visualize the heating with magnetic resonance temperature imaging. Although we were limited by the device power available at the time and thus seemed to not achieve thermal coagulation, extrapolation of the temperature measurements at the focus and on the brain surface suggests that thermal ablation will be possible with this device without overheating the brain surface, with some possible limitation on the treatment envelope. CONCLUSION Although significant hurdles remain, these findings are a major step forward in producing a completely noninvasive alternative to surgical resection for brain disorders.

scholarly journals Successful Magnetic Resonance Imaging-Guided Focused Ultrasound Surgery for Recurrent Uterine Fibroid Previously Treated with Uterine Artery Embolization

2010 ◽  
Vol 2010 ◽  
pp. 1-4
Author(s):  
Sang-Wook Yoon ◽  
Kyoung Ah Kim ◽  
Sang Heum Kim ◽  
Jong Tae Lee
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Focused Ultrasound ◽  
Resonance Imaging ◽  
Artery Embolization ◽  
Effective Treatment Option ◽  
Ultrasound Surgery ◽  
Focused Ultrasound Surgery

A 45-year-old premenopausal woman was referred to our clinic due to recurring symptoms of uterine fibroids, nine years after a uterine artery embolization (UAE). At the time of screening, the patient presented with bilateral impairment and narrowing of the uterine arteries, which increased the risk of arterial perforation during repeated UAE procedures. The patient was subsequently referred for magnetic resonance imaging-guided focused ultrasound surgery (MRgFUS) treatment. Following the treatment, the patient experienced a significant improvement in symptoms (symptom severity score was reduced from 47 to 12 by 1 year post-treatment). MR images at 3 months showed a 49% decrease in fibroid volume. There were no adverse events during the treatment or the follow-up period. This case suggests that MRgFUS can be an effective treatment option for patients with recurrent fibroids following previous UAE treatment.

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