scholarly journals Severe cutaneous adverse reaction after oral rechallenge test in a patient with fixed drug eruption due to doxycycline

2019 ◽  
Vol 5 (2) ◽  
pp. 111
Author(s):  
Ayushi Bohara ◽  
SatyendraKumar Singh
Keyword(s):  
Adverse Reaction ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Cutaneous Adverse Reaction ◽  
Fixed Drug

scholarly journals PHẢN ỨNG DA NẶNG DO THUỐC

2020 ◽  
Vol 4 (6) ◽  
Author(s):  
Nguyen Van Khiem ◽  
Le Thi Minh Huong
Keyword(s):  
Adverse Reaction ◽  
Drug Reaction ◽  
Toxic Epidermal Necrolysis ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Acute Generalized Exanthematous Pustulosis ◽  
Cutaneous Adverse Reaction ◽  
Fixed Drug ◽  
Exanthematous Pustulosis

Phản ứng da nặng (Severe Cutaneous Adverse Reaction, SCAR) do thuốc là một nhóm các phản ứng dị ứng thuốc gây tổn thương nghiêm trọng đến da và niêm mạc, trong những trường hợp nặng có thể ảnh hưởng đến các cơ quan nội tạng, thậm chí gây tử vong. Ngoài thuốc, một số tác nhân nhiễm trùng như Mycoplasma pneumoniacũng có thể gây ra SCAR, đặc biệt ở trẻ em. Trong bài này, xin được tập trung vào SCAR do thuốc. SCAR bao gồm các hội chứng sau: Hội chứng Steven – Johnson (SJS) Hội chứng hoạt tử thượng bì nhiễm độc (Toxic Epidermal Necrolysis, TEN, trước đây còn được gọi là hội chứng Lyell) Hội chứng chuyển tiếp giữa SJS và TEN (SJS/TEN overlap) Hội chứng phản ứng với thuốc có triệu chứng toàn thân và tăng bạch cầu ái toan (Drug Reaction with Eosinophilia and Systemic Symtoms, DRESS). Ban mụn mủ toàn thân cấp tính (Acute Generalized Exanthematous Pustulosis, AGEP). Gần đây, phát ban cố định do thuốc thể bọng nước lan tỏa (Generalized Bullous Fixed Drug Eruption, GBFDE) cũng được một số bác sĩ xếp vào SCAR. Tuy nhiên GBFDE thường ít nguy hiểm hơn cũng như rất hiếm gặp ở trẻ em. Trong các hội chứng trên, SJS, TEN và hội chứng chuyển tiếp SJS/TEN được cho là cùng một bệnh với các mức độ nặng khác nhau. Trong bài này, chúng được kí hiệu chung là SJS-TEN

scholarly journals A case of self-treatment induced oral mucosal fixed drug eruptions associated with use of tinidazole - a case report

2021 ◽  
Vol 9 (6) ◽  
pp. 1794
Author(s):  
Swathi C. Prabhu ◽  
Harshavardhan K. Shetty
Keyword(s):  
Adverse Reaction ◽  
Case Report ◽  
Oral Mucosa ◽  
Medical Practice ◽  
Drug Eruption ◽  
Case Reports ◽  
Common Site ◽  
Fixed Drug Eruption ◽  
Drug Eruptions ◽  
Fixed Drug

Fixed drug eruptions (FDE) is a type of adverse reaction to drugs encountered in medical practice. Skin, glans penis is most common site of involvement. We hereby report a case of fixed drug eruption on oral mucosa due to tinidazole, a nitroimidazole-derivative which the patient had taken as he was suffering from gastro-intestinal distress. Very limited case reports have been found in literature with respect to tinidazole causing FDE.

scholarly journals Fixed drug eruption associated with fixed combination of fluoroquinolone-nitroimidazole

2021 ◽  
Vol 10 (5) ◽  
pp. 576
Author(s):  
R. Meenakshi ◽  
S. Nitya ◽  
S. Kiruthika ◽  
M. Shanthi
Keyword(s):  
Adverse Drug Reaction ◽  
Adverse Reaction ◽  
Drug Eruption ◽  
Fixed Combination ◽  
Fixed Drug Eruption ◽  
Combination Drug ◽  
Drug Eruptions ◽  
Fixed Drug ◽  
Erythematous Plaques ◽  
Cutaneous Adverse Drug Reaction

Fixed drug eruptions (FDE) are cutaneous adverse drug reaction characterized by well demarcated erythematous plaques which on removal of the offending agent resolves with residual hyperpigmentation patches at the site. FDE to nitroimidazoles and fluoroquinolones have nevertheless been infrequently reported. Awareness about the adverse reaction to the fluoroquinolone-nitroimidazole combination drug and also the likelihood of recurrence with same or similar drugs and the possible cross reaction is eminent. Hereby we report one such case of FDE to ciprofloxacin/tinidazole combination.

scholarly journals Self-medicated, satranidazole induced fixed drug eruption: a case report

2020 ◽  
Vol 9 (12) ◽  
pp. 1903
Author(s):  
Divyashanthi Chellathambi Malathi ◽  
Anusha Bommasani ◽  
Raman Palanisami Priyadharsini
Keyword(s):  
Drug Eruption ◽  
Causality Assessment ◽  
Past History ◽  
Systemic Exposure ◽  
Interesting Case ◽  
Probability Scale ◽  
Fixed Drug Eruption ◽  
Cutaneous Adverse Reaction ◽  
Fixed Drug ◽  
History Of

Fixed drug eruption (FDE) is described as the development of one or more annular or oval erythematous patches as a result of systemic exposure to a drug; these reactions normally resolve with hyperpigmentation and may recur at the same site with re-exposure to the drug. Repeated exposure to the offending drug may cause new lesions to develop in addition to lighting up the older hyperpigmented lesions. Here we present an interesting case of satranidazole induced FDE with a past history of FDE to the same drug 5 months back. Since the eruption occurred in the same site on re-exposure to the same drug, a diagnosis of FDE was made and causality assessment by Naranjo adverse drug reaction probability scale showed a certain relationship between the cutaneous adverse reaction and the offending drug

Fixed-drug eruption to tetracycline

1970 ◽  
Vol 101 (5) ◽  
pp. 621b-621 ◽  
Author(s):  
M. B. Brodin
Keyword(s):  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug

A Case of Fixed Drug Eruption due to Phenobarbital Used as a Premedication for Myelography.

2000 ◽  
Vol 62 (3) ◽  
pp. 343-345
Author(s):  
Kaoru MURATA ◽  
Atsushi HATAMOCHI ◽  
Hiroshi SHINKAI
Keyword(s):  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug

Two Cases of Multiple Fixed Drug Eruption due to Commercial Analgesics

2005 ◽  
Vol 67 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Yumiko KUBOTA ◽  
Juichiro NAKAYAMA
Keyword(s):  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug
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