Assessment of the central venous-to-arterial carbon dioxide tension difference (pCO2 delta) in adult patients with sepsis: a systematic review

2019 ◽  
Vol 32 (4) ◽  
pp. 1177
Author(s):  
AhmedA. M Abd El Aziz ◽  
AbdEl Rahman A Ahmed ◽  
YasserI Mohamed ◽  
KhaledM Gaballah
2010 ◽  
Vol 13 (3) ◽  
pp. 269 ◽  
Author(s):  
Alexandre Yazigi ◽  
Hicham Abou-Zeid ◽  
Fadia Haddad ◽  
Samia Madi-Jebara ◽  
Gemma Hayeck ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257314
Author(s):  
Charalampos Pierrakos ◽  
David De Bels ◽  
Thomas Nguyen ◽  
Dimitrios Velissaris ◽  
Rachid Attou ◽  
...  

Background In this prospective observational study, we evaluated the effects of fluid bolus (FB) on venous-to-arterial carbon dioxide tension (PvaCO2) in 42 adult critically ill patients with pre-infusion PvaCO2 > 6 mmHg. Results FB caused a decrease in PvaCO2, from 8.7 [7.6−10.9] mmHg to 6.9 [5.8−8.6] mmHg (p < 0.01). PvaCO2 decreased independently of pre-infusion cardiac index and PvaCO2 changes during FB were not correlated with changes in central venous oxygen saturation (ScvO2) whatever pre-infusion CI. Pre-infusion levels of PvaCO2 were inversely correlated with decreases in PvaCO2 during FB and a pre-infusion PvaCO2 value < 7.7 mmHg could exclude a decrease in PvaCO2 during FB (AUC: 0.79, 95%CI 0.64–0.93; Sensitivity, 91%; Specificity, 55%; p < 0.01). Conclusions Fluid bolus decreased abnormal PvaCO2 levels independently of pre-infusion CI. Low baseline PvaCO2 values suggest that a positive response to FB is unlikely.


2011 ◽  
Vol 70 (4) ◽  
pp. 1014-1015
Author(s):  
Alexandre Yazigi ◽  
Hicham Abou-Zeid ◽  
Fadia Haddad ◽  
Samia Madi-Jebara ◽  
Khalil Jabbour

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