scholarly journals High-Pressure Protein X-Ray Crystallography

2017 ◽  
Vol 27 (1) ◽  
pp. 18-25
Author(s):  
Nobuhisa WATANABE ◽  
Hiroyuki YAMADA ◽  
Takayuki NAGAE
Keyword(s):  
High Pressure ◽  
X Ray ◽  
X Ray Crystallography ◽  
Protein X

C−H- - -O Hydrogen Bonds in β-Sheetlike Networks:  Combined X-ray Crystallography and High-Pressure Infrared Study

2003 ◽  
Vol 125 (40) ◽  
pp. 12358-12364 ◽  
Author(s):  
Kwang Ming Lee ◽  
Hai-Chou Chang ◽  
Jyh-Chiang Jiang ◽  
Jack C. C. Chen ◽  
Hsiang-En Kao ◽  
...  
Keyword(s):  
High Pressure ◽  
Hydrogen Bonds ◽  
Infrared Study ◽  
X Ray ◽  
X Ray Crystallography

scholarly journals Compressibility Studies of Zirconium Based Metal-Organic Frameworks

2014 ◽  
Vol 70 (a1) ◽  
pp. C157-C157
Author(s):  
Claire Hobday ◽  
Stephen Moggach ◽  
Carole Morrison ◽  
Tina Duren ◽  
Ross Forgan
Keyword(s):  
High Pressure ◽  
Mechanical Stability ◽  
Metal Organic Frameworks ◽  
External Pressure ◽  
X Ray Diffraction ◽  
X Ray ◽  
X Ray Crystallography ◽  
Pressure Medium ◽  
Metal Organic ◽  
University Of Oslo

Metal-organic frameworks (MOFs) are a well-studied class of porous materials with the potential to be used in many applications such as gas storage and catalysis.[1] UiO-67 (UiO = University of Oslo), a MOF built from zirconium oxide units connected with 4,4-biphenyldicarboxylate (BDC) linkers, forms a face centred cubic structure. Zirconium has a high affinity towards oxygen ligands making these bridges very strong, resulting in UiO-based MOFs having high chemical and thermal stability compared to other MOF structures. Moreover, UiO-67 has become popular in engineering studies due to its high mechanical stability.[2] Using high pressure x-ray crystallography we can exert MOFs to GPa pressures, experimentally exploring the mechanical stability of MOFs to external pressure. By immersing the crystal in a hydrostatic medium, pressure is applied evenly to the crystal. On surrounding a porous MOF with a hydrostatic medium composed of small molecules (e.g. methanol), the medium can penetrate the MOF, resulting in medium-dependant compression. On compressing MOF-5 (Zn4O(BDC)3) using diethylformamide as a penetrating medium, the framework was shown to have an increased resistance to compression, becoming amorphous several orders of magnitude higher in pressure than observed on grinding the sample.[3] Here we present a high-pressure x-ray diffraction study on the UiO-based MOF UiO-67, and several new synthesised derivatives built from same metal node but with altered organic linkers, allowing us to study in a systematic way, the mechanical stability of the MOF, and its pressure dependence on both the linker, and pressure medium.

X-ray Crystallography at High Pressure to Probe Conformational Fluctuations in Biological Macromolecules

2007 ◽  
Author(s):  
Eric Girard ◽  
Richard Kahn ◽  
Anne-Claire Dhaussy ◽  
Isabella Ascone ◽  
Mohamed Mezouar ◽  
...  
Keyword(s):  
High Pressure ◽  
Biological Macromolecules ◽  
X Ray ◽  
X Ray Crystallography

Protein X-ray Crystallography in Drug Discovery

2005 ◽  
pp. 373-455 ◽  
Author(s):  
Peter Nollert ◽  
Michael D. Feese ◽  
Bart L. Staker ◽  
Hidong Kim
Keyword(s):  
Drug Discovery ◽  
X Ray ◽  
X Ray Crystallography ◽  
Protein X

Principles of Protein X-Ray Crystallography. Jan Drenth

2000 ◽  
Vol 75 (1) ◽  
pp. 48-48
Author(s):  
Gregory A. Petsko
Keyword(s):  
X Ray ◽  
X Ray Crystallography ◽  
Protein X

Incorporation of β-selenolo[3,2-b]pyrrolyl-alanine into proteins for phase determination in protein X-ray crystallography

2001 ◽  
Vol 309 (4) ◽  
pp. 925-936 ◽  
Author(s):  
Jae Hyun Bae ◽  
Stefan Alefelder ◽  
Jens T Kaiser ◽  
Rainer Friedrich ◽  
Luis Moroder ◽  
...  
Keyword(s):  
Phase Determination ◽  
X Ray ◽  
X Ray Crystallography ◽  
Protein X
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