scholarly journals Comparison of N-Terminal Pro B-Natriuretic Peptide and Echocardiographic Indices in Patients with Mitral Regurgitation

2010 ◽  
Vol 4 ◽  
pp. CMC.S6062
Author(s):  
Shokoufeh Hajsadeghi ◽  
Niloufar Samiei ◽  
Masoud Moradi ◽  
Maleki Majid ◽  
Ladan Kashani ◽  
...  
Keyword(s):  
Plasma Level ◽  
Serum Level ◽  
Mitral Regurgitation ◽  
Natriuretic Peptide ◽  
Doppler Echocardiography ◽  
Performance Index ◽  
Left Ventricular ◽  
Myocardial Performance ◽  
Lv Dysfunction ◽  
Dead End

Introduction Echocardiographic indices can form the basis of the diagnosis of systolic and diastolic left ventricular (LV) dysfunction in patients with Mitral regurgitation (MR). However, using echocardiography alone may bring us to a diagnostic dead-end. The aim of this study was to compare N-Terminal pro B-natriuretic peptide (BNP) and echocardiographic indices in patients with mitral regurgitation. Methods 2D and Doppler echocardiography and BNP serum level were obtained from 54 patients with organic mild, moderate and severe MR. Results BNP levels were increased with symptoms in patients with mitral regurgitation (NYHAI: 5.7 ± 1.1, NYHAII: 6.9 ± 1.5, NYHAIII: 8.3 ± 2 pg/ml, P < 0.001). BNP plasma level were significantly correlated with MPI (myocardial performance index) (r = 0.399, P = 0.004), and following echocardiographic indices: LVEDV (r = 0.45, P < 0.001), LVESV (r = 0.54, P < 0.001), LVEDD (r = 0.48, P < 0.001), LVESD (r = 0.54, P < 0.001), dp/dt (r = −0.32, P = 0.019) and SPAP (r = 0.4, P = 0.006). Conclusion The present study showed that BNP may be useful in patients with MR and may confirm echocardiographic indices.

Abstract 2286: Pseudonormalization Tendency of the Tei Index at High Filling Pressures -A Serious Limitation for its Use as a Myocardial Performance Index

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Michael Dandel ◽  
Hans Lehmkuhl ◽  
Dagmar Kemper ◽  
Roland Hetzer
Keyword(s):  
Diastolic Dysfunction ◽  
Performance Index ◽  
Continuous Wave ◽  
Systolic Dysfunction ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Myocardial Performance ◽  
Tei Index ◽  
Ejection Time ◽  
Lv Dysfunction

Background: The potential advantage provided by the combination of systolic and diastolic parameters makes the Tei index (myocardial performance index) attractive. This index is prolonged during mild or moderate left ventricular (LV) systolic dysfunction. The influence of diastolic dysfunction is unclear. We assessed the reliability of the Tei index for the evaluation of LV dysfunction, in relation to the severity of systolic and/or diastolic impairment. Methods: To evaluate the systolic LV dysfunction associated with various degrees of diastolic dysfunction by the Tei index, the isovolumetric contraction and relaxation time (IVCT and IVRT) and the ejection time were measured by continuous wave Doppler in 155 consecutive patients accepted for heart transplantation (HTx) because of advanced dilated cardiomyopathy (DCM). To evaluate the diastolic dysfunction by the Tei index, the same Doppler measurements were performed in 200 HTx patients who showed isolated diastolic LV dysfunction with normal ejection fraction (LVEF ≥ 55%). Results: Although the Tei index was prolonged (0.67 ±0.16) in DCM patients, there was no correlation between LVEF and Tei index. The Tei index was even lower in NYHA IV in comparison to NYHA II–III patients (0.56 ±0.11 vs. 0.76 ±0.14; p <0.001)). The LVEF was 17.5 ±5% in NYHA IV and 27.2 ±6% in NYHA II–III patients (p <0.01). The IVRT was shorter (p<0.001) in NYHA IV (60.8 ±13 ms) than in NYHA II–III patients (113.9 ±19.5 ms). After HTx, due to initially prolonged IVRT, the Tei index was higher before than after the 1 st post-HTx year (0.54 ±0.08 vs. 0.45 ±0.08; p<0.01). The Tei index was also lower (p<0.05) in patients with coronary allograft vasculopathy (CAV), than in those without (0.42 ±0.10 vs. 0.48 ±0.09). For both DCM and HTx patients there was a correlation between IVRT and Tei index (p <0.001; r = 0.71 and r =0.72, respectively) and also between LV enddiastolic pressure and Tei index (p <0.001; r = −0.69 and r = −0.74, respectively). Conclusions: The shortening of the IVRT due to the elevation of filling pressures in both severe systolic dysfunction (i.e. advanced DCM) and isolated diastolic dysfunction (post-HTx CAV) lowers the Tei index (pseudo-normalization tendency) and thus, in these clinical situations, the Tei index becomes misleading.

Myocardial performance after successful intervention for native aortic coarctation

2010 ◽  
Vol 20 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Vedide Tavli ◽  
Turkay Saritas ◽  
Baris Guven ◽  
Faik Okur ◽  
Berna Cevik Saylan ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Performance Index ◽  
Aortic Coarctation ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Myocardial Performance ◽  
Left Ventricular Performance ◽  
Ventricular Performance ◽  
Endothelin 1 ◽  
Isovolumic Relaxation

AbstractCoarctation of the aorta is associated with increased risk for hypertension in adulthood, despite successful repair. The intrinsic mechanisms underscoring hypertension and left ventricular performance in these patients, however, remains to be determined. Our objective was to evaluate left ventricular performance by means of echocardiographic and biochemical parameters at midterm follow-up in normotensive children who have had undergone successful surgical or catheter interventional treatment of coarctation with a residual gradient of less than 20 mmHg at rest. We studied prospectively 14 patients with native aortic coarctation who underwent surgery or balloon angioplasty, the cohort made up of equal numbers of boys and girls, and having a mean age of 8.5 plus or minus 4 years. We also studied 30 age-matched healthy subjects, measuring mitral inflow pulsed wave signals, isovolumic relaxation and contraction times, myocardial performance index parameters, and levels of B-type natriuretic peptide and endothelin-1 in both groups. We found no differences in systolic blood pressure at rest between the patients and their controls. The ventricular septal diastolic dimensions, left ventricular posterior wall dimensions, mitral valve E wave, deceleration time, isovolumic relaxation time, isovolumic contraction time and myocardial performance index were all significantly increased in the patients. Levels of plasma B-type natriuretic peptide and endothelin-1 were also significantly higher in the patients when compared to the control group. We conclude that aortic coarctation is a chronic disease characterized by persistency of myocardial and vascular alterations. The elevated levels of plasma b-type natriuretic peptide and endothelin-1 may be indicative of late onset hypertension after successful treatment of native coarctation in early childhood.

scholarly journals Abnormal myocardial performance index in M-mode color tissue Doppler-echocardiography

2020 ◽  
Vol 26 (1) ◽  
pp. 36-43
Author(s):  
Andrey Ivanov ◽  
Nikolay Runev ◽  
Emil Manov ◽  
Elisaveta Levunlieva
Keyword(s):  
Doppler Echocardiography ◽  
Performance Index ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Tissue Doppler Echocardiography ◽  
Myocardial Performance ◽  
Pulsed Doppler ◽  
Pulsed Doppler Echocardiography ◽  
Color Tissue Doppler

The myocardial performance index (MPI) is used for global systolic-diastolic left ventricular function and prognosis assessment in patients with heart disease, allowing assessment of the patient‘s current condition and disease development follow-up. The classic method of calculation is pulsed Doppler echocardiography. The aim of the study was to evaluate the correlation of myocardial performance index with established left ventricular systolic and diastolic function indices and to determine cut-off values of the myocardial performance index in M-mode color tissue Doppler echocardiography through the aortic and mitral valves predicting abnormal myocardial performance index by pulsed Doppler echocardiography. One hundred and fi ve subjects were studied, including 30 healthy controls, 45 hypertensive patients, and 30 patients with CHD. MPI was calculated using pulsed Doppler (MPIPW) and M-mode color tissue Doppler echocardiography through the aortic (MPIAO1 and MPIAO2) and mitral (MPIMV) valves. In all patients, the myocardial performance index showed a low to moderatenegative correlation with the left ventricular ejection fraction, and the correlation with the diastolic function indices was moderate to high. In healthy persons, the correlations were not signifi cant in almost all comparisons. The MPIAO1, MPIAO2,and MPIMV values predicting abnormal MPI by pulsed Doppler (MPIPW ≥ 0.50) are MPIAO1 ≥ 0.578, MPIAO2 ≥ 0.446, and MPIMV ≥ 0.552. The cut-off values of MPI by M-mode color tissue Doppler echocardiography through the aortic and mitral valve obtained can be used for global left ventricular function assessment in patients with heart disease. Further studies, on a larger number of patients, are necessary to estimate the predictive value of the parameters established.

scholarly journals Tissue Doppler Echocardiography and Myocardial Performance Index in Patients with Scleroderma

2005 ◽  
Vol 33 (4) ◽  
pp. 417-425 ◽  
Author(s):  
S Güllülü ◽  
AA Kaderli ◽  
A Ekbul ◽  
B Özdemir ◽  
İ Baran ◽  
...  
Keyword(s):  
Doppler Echocardiography ◽  
Performance Index ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Tissue Doppler Echocardiography ◽  
Doppler Imaging ◽  
Control Group ◽  
Myocardial Performance ◽  
Ventricular Functions

In this study, left and right ventricular functions were examined echocardiographically in 22 patients with scleroderma and 22 healthy volunteers. Conventional and tissue Doppler echocardiography and myocardial performance indexes were used as measures of right and left ventricular global functions. Mitral early diastolic E wave deceleration time, isovolumetric contraction time and left ventricular myocardial performance index and peak tricuspid A wave velocity were significantly higher in the scleroderma group compared with the control group. Mitral and tricuspid E/A ratios were significantly lower in patients with scleroderma. In addition, mitral annular and tricuspid annular isovolumetric relaxation times and the tricuspid E/E' ratio were significantly increased in scleroderma patients compared with the control group. In conclusion, in scleroderma patients the global left ventricular functions were depressed and diastolic function abnormalities were seen in both right and left ventricles. In addition, longitudinal muscle functions of the ventricles were depressed in scleroderma patients, as shown by tissue Doppler imaging parameters.

Utility of myocardial performance index measured by left ventricular catherization

2005 ◽  
Vol 60 (4) ◽  
pp. 415-420 ◽  
Author(s):  
Mustafa OZKAN ◽  
Mehmet UZUN ◽  
Kursad ERINC ◽  
Cem KOZ ◽  
Oben BAYSAN ◽  
...  
Keyword(s):  
Performance Index ◽  
Left Ventricular ◽  
Myocardial Performance Index ◽  
Myocardial Performance
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