scholarly journals Lemierre Syndrome: Two Preschool Children with Cerebral Infarcts

2008 ◽  
Vol 1 ◽  
pp. CMPed.S879
Author(s):  
Miriam Santschi ◽  
Michèle David ◽  
Laurent Garel ◽  
Michel Vanasse ◽  
France Gauvin
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Left Internal Jugular Vein ◽  
Cerebral Infarcts ◽  
Jugular Vein Thrombosis ◽  
Lemierre Syndrome ◽  
Vein Thrombosis ◽  
First Case ◽  
One Year

We report two children who developed hemiparesis secondary to cerebral infarcts complicating Lemierre syndrome. The first case is a one-year-old patient who presented a left internal jugular vein thrombosis and a left carotid compression due to retropharyngeal cellulitis. The second case is a five-year-old girl who presented a left internal jugular vein and a right carotid artery thrombosis associated with an oropharyngeal cellulitis. Etiologic agents involved were Staphylococus aureus in the first case and Fusobacterium necrophorum in the second case. These cases call for vigilance among physicians for this rare syndrome, its unusual presentation and its associated severe complications.

scholarly journals Bilateral Internal Jugular Vein Thrombosis: An Unusual Presentation of Lemierre Syndrome

2016 ◽  
Vol 2 (2) ◽  
pp. 70-72
Author(s):  
Arpit Saxena ◽  
◽  
A V Ramesh ◽  
Poonam Raj Mehra ◽  
E. Nikhilesh ◽  
...  
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Unusual Presentation ◽  
Jugular Vein Thrombosis ◽  
Lemierre Syndrome ◽  
Vein Thrombosis ◽  
Internal Jugular Vein Thrombosis

scholarly journals A case of Lemierre-like Syndrome: internal jugular vein thrombosis secondary to Staphylococcus aureus sternoclavicular joint septic arthritis

2019 ◽  
Vol 2019 (7) ◽  
Author(s):  
Chaozer Er ◽  
Vanessa Hwee Ting Tey ◽  
Navin Kuthiah ◽  
Veeraraghavan Meyyur Aravamudan
Keyword(s):  
Staphylococcus Aureus ◽  
Septic Arthritis ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Sternoclavicular Joint ◽  
Jugular Vein Thrombosis ◽  
Lemierre Syndrome ◽  
Vein Thrombosis ◽  
Oropharyngeal Infection ◽  
Responsible Pathogen

Abstract Lemierre syndrome is the internal jugular vein (IJV) suppurative thrombophlebitis, usually secondary to oropharyngeal infection. Staphylococcus aureus is an emerging responsible pathogen. We report a unique case of IJV thrombosis secondary to methicillin-susceptible S. aureus sternoclavicular joint septic arthritis. We review the existing literature on Lemierre syndrome: its various manifestations, causative pathogens, treatment and management.

scholarly journals Postoperative diagnostics clinical case of the patient with kidney canсer metastasis in the thyroid gland in combination with left internal jugular vein thrombosis

2017 ◽  
Vol 11 (1) ◽  
pp. 45-50
Author(s):  
Taras S. Panevin ◽  
Liliya S. Selivanova ◽  
Nonna V. Latkina ◽  
Nikolay S. Panevin
Keyword(s):  
Thyroid Gland ◽  
Internal Jugular Vein ◽  
Clinical Case ◽  
Jugular Vein ◽  
Left Internal Jugular Vein ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
Internal Jugular Vein Thrombosis

Представлено клиническое наблюдение пациентки 68 лет с жалобами на увеличение в размерах шеи, преимущественно с левой стороны, ощущение першения в горле. В ходе обследования по данным УЗИ органов шеи выявлено конгломератное образование левой доли щитовидной железы. Кроме того, в просвете в верхней трети внутренней яремной вены выявлено образование средней эхогенности. По данным последующей тонкоигольной биопсии левой доли – признаки коллоидного зоба. Пациентке проведено оперативное лечение в объеме левосторонней гемитиреоидэктомии: при ревизии левая доля значительно увеличена в размерах за счет узлового образования, доходящего до левого угла нижней челюсти, располагающегося частично загрудинно и за трахеей. По данным послеоперационного гистологического исследования выявлен метастаз светлоклеточного рака почки в левую долю щитовидной железы с признаками прорастания в окружающие сосуды и мышцы.

scholarly journals Lemierre Syndrome in a Patient With Splenectomy Secondary to Pyruvate Kinase Deficiency, Complicated by Heparin Resistance

2021 ◽  
Vol 9 ◽  
pp. 232470962110406
Author(s):  
Kiley Clark ◽  
Morgan Sly ◽  
Pearl Chan ◽  
Hobart Lai ◽  
Hadi Ali ◽  
...  
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Transverse Sinus ◽  
Jugular Vein Thrombosis ◽  
Lemierre Syndrome ◽  
Jugular Veins ◽  
Vein Thrombosis ◽  
Heparin Resistance ◽  
Mandibular Molar ◽  
Oropharyngeal Infection

Lemierre syndrome was first documented in the literature in 1936, and is defined as septic thrombophlebitis of the internal jugular vein. It is typically a result of oropharyngeal infection causing local soft tissue inflammation, which spreads to vasculature, and promotes formation of septic thrombi within the lumen, persistent bacteremia, and septic emboli. We present the case of a 24-year-old incarcerated man, who presented with leukocytosis and a right-sided tender, swollen neck after undergoing left mandibular molar extraction for an infected tooth. Computed tomography revealed a persistent thrombus in the transverse and sigmoid sinuses bilaterally, extending downwards, into the upper jugular veins. He was started on empiric intravenous vancomycin, zosyn, and heparin, but subsequently demonstrated heparin resistance, and was thus anticoagulated with a lovenox bridge to warfarin. Throughout his hospital course, hemocultures demonstrated no growth, so antibiotic treatment was deescalated to oral metronidazole and ceftriaxone. On discharge, the patient was transitioned to oral amoxicillin and metronidazole for an additional 4 weeks with continuation of anticoagulation with warfarin for a total of 3 to 6 months. This case report details a unique presentation of Lemierre syndrome with bilateral transverse sinus, sigmoid sinus, and internal jugular vein thrombosis that was presumably secondary to an odontogenic infectious focus.

scholarly journals Bilateral Lemierre's Syndrome: A Case Report and Literature Review

2002 ◽  
Vol 81 (4) ◽  
pp. 234-252 ◽  
Author(s):  
Brian A. Moore ◽  
Catherine Dekle ◽  
Jay Werkhaven
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Fusobacterium Necrophorum ◽  
Lemierre’S Syndrome ◽  
Jugular Vein Thrombosis ◽  
Jugular Veins ◽  
Vein Thrombosis ◽  
Warfarin Sodium ◽  
Oropharyngeal Infection ◽  
Lemierre's Syndrome

Lemierre's syndrome is characterized by thrombosis of the internal jugular vein that develops following an oropharyngeal infection. Sepsis and septic metastases frequently ensue and affect the lungs, the musculoskeletal system, and occasionally the liver. Most cases are caused by infection with Fusobacterium necrophorum. This infection responds to antibiotic therapy with beta-lactamase-resistant compounds that exert good anaerobic coverage. Anticoagulation and surgical intervention can be helpful in advanced cases. Fewer than 160 cases of classic Lemierre's syndrome have been described; approximately one-third of these reported cases have occurred since 1988. We describe a new case of Lemierre's syndrome that occurred in an otherwise healthy 27-year-old man. Thrombosis of both internal jugular veins extended through the subclavian system and into both upper extremities. The patient was treated with intravenous antibiotics and heparin during 14 days of hospitalization. He was discharged on oral clindamycin and warfarin sodium, and after 6 months he was able to return to full activity. To our knowledge, this is the first reported case of Lemierre's syndrome in which internal jugular vein thrombosis occurred bilaterally. By reporting this previously undescribed manifestation of Lemierre's syndrome, we hope to increase practitioner awareness of this disease entity.

scholarly journals Paraneoplastic Internal Jugular Vein Thrombosis Leading to Diagnosis of Bilateral Ovarian Ependymoma

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Irappa Madabhavi ◽  
Apurva Patel ◽  
Mukesh Choudhary ◽  
Asha Anand
Keyword(s):  
Internal Jugular Vein ◽  
World Literature ◽  
Jugular Vein ◽  
Blood Chemistry ◽  
Small Cells ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
First Case ◽  
Internal Jugular Vein Thrombosis ◽  
The Right

Ovarian ependymomas are extremely rare tumors of the ovary. We present a case of a 67-year-old lady presented to us with swelling in the right side of neck for 2 months followed by pelvic pain, lower abdominal distention, and weight loss for 1 month. Her coagulation profile, blood chemistry, lipid profile, and tumor markers were within normal limits. Neck Doppler ultrasonography revealed thrombus in the right internal jugular vein and CT scan of the abdomen showed bilateral ovarian masses. Patient was subjected to debulking surgery for suspected ovarian cancer and microscopy revealed a highly cellular tumor composed of small cells with hyperchromatic, round-to-oval nuclei with scanty cytoplasm, and perivascular pseudorosettes. Diagnosis was confirmed by immunophenotype showing strong positivity to glial fibrillary acidic protein, estrogen receptors, and progesterone receptors. Patient was successfully managed with anticoagulants, adjuvant chemotherapy with BEP regimen, and letrozole. After ruling out other common conditions for thrombosis in this age group, this seems to be a paraneoplastic presentation of ovarian malignancy that preceded the diagnosis of ependymoma by 2 months. To the best of our knowledge this is the first case report in the world literature as “paraneoplastic internal jugular vein thrombosis leading to diagnosis of bilateral ovarian ependymoma.”

scholarly journals A unique case of Lemierre’s syndrome status post blunt cervical trauma

Vascular ◽  
2020 ◽  
Vol 28 (4) ◽  
pp. 485-488
Author(s):  
John M Denesopolis ◽  
Ratna C Medicherla Singh ◽  
Amit R Shah ◽  
Ross Lyon ◽  
Edward Chao ◽  
...  
Keyword(s):  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Blood Cultures ◽  
Left Internal Jugular Vein ◽  
Lemierre’S Syndrome ◽  
Cervical Trauma ◽  
Jugular Vein Thrombosis ◽  
Vein Thrombosis ◽  
Left Neck ◽  
Lemierre's Syndrome

Background Lemierre’s syndrome is a rare but potentially fatal condition. The course is characterized by acute tonsillopharyngitis, bacteremia, internal jugular vein thrombosis, and septic embolization. There have been some cases secondary to penetrating trauma to the neck. Literature review has yielded no cases secondary to blunt neck trauma in the absence of oropharyngeal injury. We aim to shed light on this unique cause of Lemierre’s syndrome, so as to raise the index of suspicion for clinicians working up patients with blunt cervical trauma. Methods We present a case of a 25-year-old male restrained driver who presented with left neck and shoulder pain with a superficial abrasion to the left neck from the seatbelt who was discharged same day by the Emergency Room physicians. He returned to the Emergency Department two days later with abdominal pain. As a part of his repeat evaluation, a set of blood cultures were sent and was sent home that day. The patient was called back to the hospital one day later as preliminary blood cultures were positive for Gram positive cocci and Gram negative anaerobes. Computerized tomography scan of the neck revealed extensive occlusive left internal jugular vein thrombosis and fluid collections concerning for abscesses, concerning for septic thrombophlebitis. The patient continued to decompensate, developing severe sepsis complicated by disseminated intravascular coagulation. Results The patient underwent a left neck exploration with en bloc resection of the left internal jugular vein, drainage of abscesses deep to the sternocleidomastoid, and washout/debridement of necrotic tissue. Direct laryngoscopy at the time of surgery revealed no injury to the aerodigestive tract. Wound cultures were consistent with blood cultures and grew Fusobacterium necrophorum, Staphylococcus epidermidis, and Methicillin-resistant staphylococcus aureus. The patient underwent two subsequent operative wound explorations without any evidence of residual infection. The patient was discharged home on postoperative day 13 on a course of antibiotics and aspirin. Conclusion This case illustrates the importance of diagnosis of Lemierre’s syndrome after an unconventional inciting event (blunt cervical trauma) and appropriate treatment.

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