scholarly journals Non-small Cell Lung Cancer (NSCLC) Presenting as Isolated Facial Nerve Palsy from Metastasis to Temporal Bone: A Report Discussing Unique Presentation and Evolution with Diagnostic and Management Dilemmas

2010 ◽  
Vol 1 ◽  
pp. IJCM.S4894
Author(s):  
Manpreet Singh Tiwana ◽  
Shrinivas Rathod ◽  
Tejpal Gupta ◽  
Jai Prakash Agarwal

We present the case of a 67-year-old man with a three month history of right sided facial nerve palsy reporting to our clinic for evaluation of a recently seen suspicious mass in the right lung. Subsequently he was diagnosed with advanced NSCLC right lung and started on palliative chemotherapy. Furthermore, temporal bone metastasis was discovered on radiological imaging while investigating symptoms of acute mastoiditis and persisting facial neuralgia, a symptom completely overlooked at first as Idiopathic Bell's palsy. This presentation is exceptionally unique, although temporal bone metastasis arising from established primary lung or other malignancies is itself rare, and predilect to a later onset in the natural history of the disease, as reported in the literature. None of the published literature report neither addresses the optimal management course nor its subsequent impact on quality of life of patients with temporal bone metastasis.

2019 ◽  
Vol 47 (8) ◽  
pp. 4014-4018 ◽  
Author(s):  
Bo Zhang ◽  
Yunpeng Hao ◽  
Yanfeng Zhang ◽  
Nuo Yang ◽  
Hang Li ◽  
...  

Background Kawasaki disease (KD) is an acute multisystem vasculitic syndrome that predominantly affects infants and young children. Neurological complications are rare in patients with KD and the diagnosis is challenging. We report a case of KD that manifested as bilateral facial nerve palsy and meningitis. Case report A 6-month-old boy presented with a 10-day history of fever. Four days before admission, the patient developed a rash, conjunctival injection, perioral and perianal excoriation, and bilateral facial nerve palsy. Brain magnetic resonance imaging was normal. Echocardiography showed dilated coronary arteries and coronary artery aneurysms. A cerebrospinal fluid examination showed an elevated leukocyte count. A diagnosis of KD was made, and the patient was treated with gamma globulin and aspirin. The patient’s fever subsided on the following day and the right-sided facial nerve palsy was relieved 1 month later. An 18-month follow-up showed that the left-sided facial nerve palsy persisted and the patient’s condition remained stable. Conclusion KD manifesting as bilateral facial nerve palsy and meningitis is extremely rare. Clinicians should be aware of this condition, and early diagnosis and appropriate treatment should be emphasized.


Author(s):  
Lham Dorjee ◽  
Manu C.B. ◽  
Suvamoy Chakraborty ◽  
Abijeet Bhatia

<p class="abstract">Tuberculosis (TB) of the temporal bone is a rare condition. Tubercular otomastoiditis presenting with Citelli’s abscess, facial nerve palsy and extensive bone destruction is an unusual condition. As far as we know this maybe the first reported case with the above diagnosis. A 26 year old male patient presented with chronic right ear discharge, decreased hearing and right side facial nerve palsy with tender fluctuant swelling in the right post aural region approximately 10×8 cm in dimension, posterior to the mastoid tip and extending into the occipital region, almost reaching up to the midline posteriorly. High resolution computed tomography (CT) scan of temporal bone and magnetic resonance imaging (MRI) of brain was done. He underwent right side mastoid exploration and drainage of the abscess under general anaesthesia. The specimens sent for investigations revealed acid fast bacilli suggestive of <em>Mycobacterium tuberculosis</em> and the patient was started on anti-tubercular therapy. In all cases of long-standing chronic otitis media (COM) especially in those with complications, possibility of TB should be ruled out. High index of suspicion is needed for early diagnosis and treatment and to prevent dreaded complications in such patients.</p>


2005 ◽  
Vol 20 (7) ◽  
pp. 1131-1132 ◽  
Author(s):  
Michiaki Nagai ◽  
Hiroyasu Yamada ◽  
Mikiya Kitamoto ◽  
Junko Ikeda ◽  
Yoshiki Mori ◽  
...  

2020 ◽  
Vol 6 (1) ◽  
pp. 1-5
Author(s):  
Daichi Fujii ◽  
Hikari Shimoda ◽  
Natsumi Uehara ◽  
Takeshi Fujita ◽  
Masanori Teshima ◽  
...  

2021 ◽  
Vol 10 (4) ◽  
pp. 578
Author(s):  
Izabela Nowak-Gospodarowicz ◽  
Marek Rękas

Implantation of gold weights into the upper eyelid is a proven method of treating lagophthalmos and exposure keratopathy in patients with unresolved facial nerve palsy. The aim of this study was to evaluate the factors affecting visual acuity and corneal complications in patients after upper eyelid gold weight lid loading. Material and methods: This prospective consecutive clinical study was conducted in years 2012–2018. In total, 59 people (40 women, 19 men aged 55.5 ± 17.4 years) meeting the inclusion criteria were treated with gold weights. The ordered multinomial logit model was used to analyze the factors affecting best-corrected visual acuity (BCVA) and degree of exposure keratopathy after surgery. The influence of the following variables was analyzed: patient age, etiology and duration of the facial nerve palsy, history of the previous eyelid surgery, degree of lagophthalmos in mm, presence of Bell’s phenomenon, and corneal sensation, Schirmer test results. Results: Implantation of gold weights into the upper eyelid effectively reduced lagophthalmos and exposure keratopathy in the study group (p < 0.001). BCVA was maintained or better in 95% of patients after surgery. Patient age, presence of the Bell’s phenomenon, and corneal sensation significantly affected the final BCVA (p < 0.1). The presence of Bell’s phenomenon and corneal sensation had a positive effect on the degree of keratopathy after surgery (p < 0.1). In turn, patient age and history of tarsorrhaphy were significant negative prognostic factors of exposure keratopathy and BCVA after surgery (p < 0.05). Etiology and duration of facial nerve palsy, degree of corneal exposure in mm, and results of the Schirmer test did not have a significant impact on the outcome after surgery (p > 0.1). Conclusions: The results of our study may help to answer the question of how to direct ophthalmologists and other specialists who refer to ophthalmologists for management advice in patients with facial nerve palsy. Elderly patients with a history of tarsorrhaphy who present with poor Bell’s phenomenon and/or a lack of corneal sensation should be the first candidates for immediate correction of lagophthalmos.


2016 ◽  
Vol 13 (03) ◽  
pp. 168-170
Author(s):  
Kanjully Sabarigirish ◽  
Sanjeev Saxena ◽  
Himanshu Swami ◽  
Angshuman Dutta ◽  
Lohith BR

2016 ◽  
Vol 130 (S3) ◽  
pp. S164-S165
Author(s):  
Keishi Fujiwara ◽  
Yasushi Furuta ◽  
Shinya Morita ◽  
Atsushi Fukuda ◽  
Akihiro Homma ◽  
...  

2019 ◽  
Vol 48 (3) ◽  
pp. 030006051986749
Author(s):  
Yu-Ming Liu ◽  
Yan-Li Chen ◽  
Yan-Hua Deng ◽  
Yan-Ling Liang ◽  
Wei Li ◽  
...  

Miller Fisher syndrome (MFS), a variant of Guillain–Barré syndrome, is characterized by ataxia, areflexia and ophthalmoplegia. This case report describes a 40-year old male that presented with a 3-day history of unsteady walking and numbness on both hands, and a 2-day history of seeing double images and unclear articulation. Lumbar puncture revealed an opening pressure of 260 mm H2O. Plasma serology was positive for anti-ganglioside M1-immunoglobulin M (anti-GM1-IgM) antibodies and negative for anti-ganglioside Q1b (anti-GQ1b) antibodies. The patient was diagnosed with MFS based on the clinical course and neurophysiological findings. On the 4th day of treatment with intravenous immunoglobulin (IVIG), his ataxia and unsteady walking improved, but his bilateral eyeballs were fixed, and over the next few days he developed bilateral peripheral facial paralysis. After 5 days of IVIG treatment, methylprednisolone treatment was offered and the patient's symptoms gradually improved. Early intracranial hypertension and delayed facial nerve palsy may be atypical presentations of MFS. Anti-GM1-IgM antibodies may be the causative antibodies for MFS. If the IVIG therapy does not stop the progression of the disease, the addition of corticosteroid therapy may be effective. However, the relationship between IgM type, anti-GM1 antibody and MFS remains unclear and requires further research.


1997 ◽  
Vol 20 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Michael D. Weiss ◽  
Jorge C. Kattah ◽  
Raymond Jones ◽  
Herbert J. Manz

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