Anticancer metallodrugs: where is the next cisplatin?

2018 ◽  
Vol 10 (6) ◽  
pp. 615-617 ◽  
Author(s):  
Muhammad Hanif ◽  
Christian G Hartinger
Keyword(s):  
Anticancer Metallodrugs

scholarly journals Targeting translation: a promising strategy for anticancer metallodrugs

2021 ◽  
Vol 446 ◽  
pp. 214129
Author(s):  
Enrique Ortega ◽  
Gloria Vigueras ◽  
Francisco José Ballester ◽  
José Ruiz
Keyword(s):  
Promising Strategy ◽  
Anticancer Metallodrugs

Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs

2021 ◽  
Vol 60 (5) ◽  
pp. 2914-2930
Author(s):  
Oscar A. Lenis-Rojas ◽  
M. Paula Robalo ◽  
Ana Isabel Tomaz ◽  
Alexandra R. Fernandes ◽  
Catarina Roma-Rodrigues ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Half Sandwich ◽  
Anticancer Metallodrugs

scholarly journals Metalloproteomics for molecular target identification of protein-binding anticancer metallodrugs

Metallomics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1627-1636
Author(s):  
Tasha R. Steel ◽  
Christian G. Hartinger
Keyword(s):  
Protein Binding ◽  
Anticancer Agents ◽  
Target Identification ◽  
Molecular Target ◽  
Protein Targets ◽  
Anticancer Metallodrugs

The development of the metallodrug pull-down as a metalloproteomic technique has enabled the identification of the protein targets of metal-based anticancer agents.

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

2008 ◽  
Vol 51 (21) ◽  
pp. 6773-6781 ◽  
Author(s):  
Angela Casini ◽  
Chiara Gabbiani ◽  
Francesca Sorrentino ◽  
Maria Pia Rigobello ◽  
Alberto Bindoli ◽  
...  
Keyword(s):  
Cathepsin B ◽  
Thioredoxin Reductase ◽  
Protein Targets ◽  
Anticancer Metallodrugs

scholarly journals Proteomic and Metallomic Strategies for Understanding the Mode of Action of Anticancer Metallodrugs

2010 ◽  
Vol 10 (4) ◽  
pp. 324-337 ◽  
Author(s):  
Chiara Gabbiani ◽  
Francesca Magherini ◽  
Alessandra Modesti ◽  
Luigi Messori
Keyword(s):  
Mode Of Action ◽  
Anticancer Metallodrugs

Cytotoxicity and preliminary mode of action studies of novel 2-aryl-4-thiopyrone-based organometallics

2016 ◽  
Vol 45 (2) ◽  
pp. 724-733 ◽  
Author(s):  
Melanie Schmidlehner ◽  
Lea S. Flocke ◽  
Alexander Roller ◽  
Michaela Hejl ◽  
Michael A. Jakupec ◽  
...  
Keyword(s):  
Mode Of Action ◽  
Anticancer Metallodrugs

Organometallic 2-aryl-4-thiopyrone-based Ru(ii) and Rh(iii) complexes have been established and their potential as anticancer metallodrugs was investigated.

Aminophosphine ligands as a privileged platform for development of antitumoral ruthenium(ii) arene complexes

2017 ◽  
Vol 46 (46) ◽  
pp. 16113-16125 ◽  
Author(s):  
L. M. Broomfield ◽  
C. Alonso-Moreno ◽  
E. Martin ◽  
A. Shafir ◽  
I. Posadas ◽  
...  
Keyword(s):  
High Throughput ◽  
Rational Design ◽  
Potential Utility ◽  
Arene Complexes ◽  
Anticancer Metallodrugs

The potential utility of aminophosphine ligands in both high-throughput testing and rational design of new anticancer metallodrugs.

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