Conformational restriction: an effective tactic in 'follow-on'-based drug discovery

Future Medicinal Chemistry ◽

10.4155/fmc.14.50 ◽

2014 ◽

Vol 6 (8) ◽

pp. 885-901 ◽

Author(s):

Zengjun Fang ◽

Yu’ning Song ◽

Peng Zhan ◽

Qingzhu Zhang ◽

Xinyong Liu

Keyword(s):

Drug Discovery ◽

Conformational Restriction

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RNA drug discovery: Conformational restriction enhances specific modulation of the T-box riboswitch function

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2020.115696 ◽

2020 ◽

Vol 28 (20) ◽

pp. 115696

Author(s):

Ian Armstrong ◽

Ali H. Aldhumani ◽

Jia L. Schopis ◽

Fang Fang ◽

Eric Parsons ◽

...

Keyword(s):

Drug Discovery ◽

Conformational Restriction ◽

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Epigenetics for Drug Discovery

10.1039/9781782628484 ◽

2015 ◽

Keyword(s):

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Drug Discovery for Leishmaniasis

10.1039/9781788010177 ◽

2017 ◽

Keyword(s):

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Artificial Intelligence in Drug Discovery

10.1039/9781788016841 ◽

2020 ◽

Keyword(s):

Artificial Intelligence ◽

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Phenotypic Drug Discovery

10.1039/9781839160721 ◽

2020 ◽

Keyword(s):

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Drug Discovery from Natural Products

10.1039/9781849734950 ◽

2012 ◽

Keyword(s):

Natural Products ◽

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Ethnomedicine and Drug Discovery

10.1016/s1572-557x(02)x8007-6 ◽

2002 ◽

Keyword(s):

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Bioinformatics and Computational Biology in Drug Discovery and Development

10.1017/cbo9780511989421 ◽

2016 ◽

Keyword(s):

Drug Discovery ◽

Computational Biology ◽

Drug Discovery And Development

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Mass Ligand-Binding Screening Strategies for Identification of Leads for New Drug Discovery

PsycEXTRA Dataset ◽

10.1037/e495942006-003 ◽

1993 ◽

Author(s):

Ronald M. Burch ◽

Keyword(s):

Drug Discovery ◽

Ligand Binding ◽

New Drug ◽

Screening Strategies

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The Use of Conformational Restriction and Molecular Modeling Techniques in the Development of Receptor-Specific Opioid Peptide Agonists and Antagonists

PsycEXTRA Dataset ◽

10.1037/e495942006-018 ◽

1993 ◽

Author(s):

Peter W. Schiller ◽

◽

Thi M.-D. Nguyen ◽

Grazyna Weltrowska ◽

Nga N. Chung ◽

...

Keyword(s):

Molecular Modeling ◽

Opioid Peptide ◽

Conformational Restriction ◽

Modeling Techniques

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