Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: Report from a phase I/II trial

Cancer Biology & Therapy ◽

10.4161/cbt.5.4.2522 ◽

2006 ◽

Vol 5 (4) ◽

pp. 375-379 ◽

Author(s):

Tania Crombet Ramos ◽

Javier Figueredo ◽

Mauricio Catala ◽

González Sandra ◽

Julio C. Selva ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Growth Factor Receptor ◽

High Grade Glioma ◽

Epidermal Growth ◽

Download Full-text

High-Grade Glioma Formation Results from Postnatal Pten Loss or Mutant Epidermal Growth Factor Receptor Expression in a Transgenic Mouse Glioma Model

Cancer Research ◽

10.1158/0008-5472.can-06-0712 ◽

2006 ◽

Vol 66 (15) ◽

pp. 7429-7437 ◽

Author(s):

Qingxia Wei ◽

Laura Clarke ◽

Danielle K. Scheidenhelm ◽

Baoping Qian ◽

Amanda Tong ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

High Grade Glioma ◽

Receptor Expression ◽

Pten Loss ◽

Epidermal Growth ◽

Download Full-text

Phase I study of anti-epidermal growth factor receptor (anti-EGFR) antibody C225 in combination with irradiation in patients with advanced squamous cell carcinoma of the head and neck (SCCHN)

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/s0360-3016(98)80497-5 ◽

1998 ◽

Vol 42 (1) ◽

pp. 322

Author(s):

M.P. Ezekiel ◽

F. Robert ◽

R.F. Meredith ◽

S.A. Spencer ◽

J. Newsome ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Phase I Study ◽

Growth Factor Receptor ◽

Advanced Squamous Cell Carcinoma ◽

Epidermal Growth ◽

Download Full-text

A phase I study of the chimeric monoclonal anti-epidermal growth factor receptor (EGFR) antibody cetuximab as a single agent in subjects from Japan with advanced solid tumors: Safety, pharmacokinetics (PK)

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3209 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3209-3209 ◽

Author(s):

H. Yasui ◽

K. Shirao ◽

N. Yamamoto ◽

Y. Shimada ◽

Y. Yamada ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Phase I Study ◽

Single Agent ◽

Growth Factor Receptor ◽

Advanced Solid Tumors ◽

Epidermal Growth ◽

Download Full-text

Phase I study of the humanized anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with cisplatin, 5-fluorouracil and leucovorin (PFL) in patients (pts) with advanced esophago-gastric (EG) adenocarcinoma

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3156 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3156-3156 ◽

Author(s):

T. Trarbach ◽

N. Schleucher ◽

D. Weber ◽

J. Tillner ◽

I. Fassmann ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Phase I Study ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Download Full-text

A phase I pharmacokinetic (PK) and serial tumor and skin pharmacodynamic (PD) study of weekly, every 2 weeks or every 3 weeks 1-hour (h) infusion EMD72000, an humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients (p) with advanced tumors known to overexpress the EGFR

European Journal of Cancer ◽

10.1016/s0959-8049(02)80868-1 ◽

2002 ◽

Vol 38 ◽

pp. S69-S70 ◽

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Advanced Tumors ◽

Download Full-text

Faculty Opinions recommendation of Phase I study of EKB-569, an irreversible inhibitor of the epidermal growth factor receptor, in patients with advanced solid tumors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14346.471799 ◽

2006 ◽

Author(s):

Jeffrey Evans

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Solid Tumors ◽

Phase I Study ◽

Growth Factor Receptor ◽

Advanced Solid Tumors ◽

Irreversible Inhibitor ◽

Epidermal Growth

Download Full-text

A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non–small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-17-1447 ◽

2017 ◽

Vol 23 (24) ◽

pp. 7467-7473 ◽

Author(s):

Helena A. Yu ◽

Alexander Spira ◽

Leora Horn ◽

Jared Weiss ◽

Howard West ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Growth Factor Receptor ◽

Small Cell Lung ◽

Dose Escalation Study ◽

Lung Cancers ◽

Epidermal Growth

Download Full-text

A Phase I Study of an Anti-epidermal Growth Factor Receptor Monoclonal Antibody for the Treatment of Malignant Gliomas

Neurosurgery ◽

10.1097/00006123-199609000-00009 ◽

1996 ◽

Vol 39 (3) ◽

pp. 478-483 ◽

Author(s):

Thierry Faillot ◽

Henri Magdelénat ◽

Essam Mady ◽

Paul Stasiecki ◽

Denis Fohanno ◽

...

Keyword(s):

Monoclonal Antibody ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Phase I Study ◽

Malignant Gliomas ◽

Growth Factor Receptor ◽

Epidermal Growth ◽

Receptor Monoclonal Antibody

Download Full-text

A dose-escalation phase I trial of nimotuzumab, an antibody against the epidermal growth factor receptor, in patients with advanced solid malignancies

Investigational New Drugs ◽

10.1007/s10637-010-9444-0 ◽

2010 ◽

Vol 29 (5) ◽

pp. 996-1003 ◽

Author(s):

Benoit You ◽

Anthony Brade ◽

Joao M. Magalhaes ◽

Lillian L. Siu ◽

Amit Oza ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Dose Escalation ◽

Phase I Trial ◽

Growth Factor Receptor ◽

Solid Malignancies ◽

Epidermal Growth

Download Full-text

Phase I and pharmacokinetic study of BIBX 1382 BS, an epidermal growth factor receptor (EGFR) inhibitor, given in a continuous daily oral administration

European Journal of Cancer ◽

10.1016/s0959-8049(02)00020-5 ◽

2002 ◽

Vol 38 (8) ◽

pp. 1072-1080 ◽

Author(s):

Ch. Dittrich ◽

G. Greim ◽

M. Borner ◽

K. Weigang-Köhler ◽

H. Huisman ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Oral Administration ◽

Phase I ◽

Pharmacokinetic Study ◽

Growth Factor Receptor ◽

Egfr Inhibitor ◽

Epidermal Growth ◽

Daily Oral Administration

Download Full-text