Cytotoxic t-lymphocyte Antigen 4 (ctla-4) - 1661 a/g and -658 c/t Gene Polymorphisms in Autoimmune Thyroid Diseases: a Pilot Study

2011 ◽  
Vol 7 (3) ◽  
pp. 413-423
Author(s):  
I Duncea
Keyword(s):  
Pilot Study ◽  
T Lymphocyte ◽  
Gene Polymorphisms ◽  
Cytotoxic T Lymphocyte ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Lymphocyte Antigen ◽  
Autoimmune Thyroid

scholarly journals Cytotoxic T Lymphocyte-Associated Antigen 4 Gene Polymorphisms and Autoimmune Thyroid Diseases: An Updated Systematic Review and Cumulative Meta-Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Hai-Feng Hou ◽  
Xu Jin ◽  
Tao Sun ◽  
Cheng Li ◽  
Bao-Fa Jiang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Gene Polymorphism ◽  
T Lymphocyte ◽  
Gene Polymorphisms ◽  
Cytotoxic T Lymphocyte ◽  
Meta Analysis ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid ◽  
Population Analyses

The association of the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) gene and susceptibility to autoimmune thyroid diseases (AITDs) has been studied extensively. However, the results were not the same in different ethnic groups. We updated the meta-analysis of association of CTLA-4 gene polymorphisms with AITDs and summarized the results in specific ethnicity. The associations of A49G gene polymorphism with GD, A49G gene polymorphism with HT, CT60 gene polymorphism with GD, and CT60 gene polymorphism with HT were summarized based on the literatures published up to October 30, 2014, in English or Chinese languages. The participants involved in the studies of A49G with GD, A49G with HT, CT60 with GD, and CT60HT were 39004 subjects (in 51 studies), 13102 subjects (in 22 studies), 31446 subjects (in 22 studies), and 6948 subjects (in 8 studies), respectively. The pooled ORs of CTLA-4 gene polymorphisms with AITDs were larger than 1.00, and the 95% CIs of ORs were statistically significant among whole population analyses. However, the subgroup analysis demonstrated that pooled ORs of A49G polymorphisms with GD among Africans or Americans are less than 1.00. The accumulated evidence suggests that the G allele mutant of A49G and CT60 increased the risks of HT and GD.

Association of cytokine Th2 gene polymorphisms with autoimmune thyroid diseases in Tunisian population

2020 ◽  
Vol 47 (3) ◽  
pp. 294-308 ◽  
Author(s):  
Souhir Mestiri ◽  
Ines Zaaber ◽  
Oumaima Inoubli ◽  
Nabil Abid ◽  
Abir Omrani ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

Associations of gene polymorphisms in interferon‐alpha signature‐related genes with autoimmune thyroid diseases

2019 ◽  
Vol 91 (6) ◽  
pp. 860-868 ◽  
Author(s):  
Jiunn‐Diann Lin ◽  
Shun‐Fa Yang ◽  
Yuan‐Hung Wang ◽  
Wen‐Fang Fang ◽  
Kam‐Tsun Tang ◽  
...  
Keyword(s):  
Interferon Alpha ◽  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

A potential role of TNFR gene polymorphisms in autoimmune thyroid diseases in the Tunisian population

Cytokine ◽  
2008 ◽  
Vol 43 (2) ◽  
pp. 110-113 ◽  
Author(s):  
Maha Kammoun-Krichen ◽  
Noura Bougacha-Elleuch ◽  
Kaouthar Makni ◽  
Mouna Mnif ◽  
Joumaa Jouida ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Potential Role ◽  
Thyroid Diseases ◽  
Tunisian Population ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between STAT4 Gene Polymorphisms and Autoimmune Thyroid Diseases in a Chinese Population

2014 ◽  
Vol 15 (7) ◽  
pp. 12280-12293 ◽  
Author(s):  
Ni Yan ◽  
Shuai Meng ◽  
Jiaozhen Zhou ◽  
Jian Xu ◽  
Fatuma Muhali ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Chinese Population ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association between C1q gene polymorphisms and autoimmune thyroid diseases

2017 ◽  
Vol 61 (4) ◽  
pp. 337-342
Author(s):  
Qiuming Yao ◽  
Jie Li ◽  
Xiaofei An ◽  
Wenjuan Jiang ◽  
Qiu Qin ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Autoimmune Thyroid

scholarly journals Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients

2010 ◽  
Vol 53 (3) ◽  
pp. 537-541 ◽  
Author(s):  
Satoru Joshita ◽  
Takeji Umemura ◽  
Kaname Yoshizawa ◽  
Yoshihiko Katsuyama ◽  
Eiji Tanaka ◽  
...  
Keyword(s):  
Primary Biliary Cirrhosis ◽  
Association Analysis ◽  
T Lymphocyte ◽  
Gene Polymorphisms ◽  
Cytotoxic T Lymphocyte ◽  
Japanese Patients ◽  
Biliary Cirrhosis ◽  
Lymphocyte Antigen
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