Detection is a major challenge for the utilization of multiple-input multiple-output (MIMO) system. Even the fixed sphere decoding (FSD), which is known for its simplicity in calculation, requests too much computation in high order modulation and large number antenna system especially for mobile battery-operated devices. In this paper, a reduced FSD algorithm is proposed to simplify the calculation complexity of the FSD while maintaining the performance at the same time. Simulation results in a 4×4, 16-QAM system show that up to 89% calculation can be saved while the performance drop is less than 0.1dB when SNR=24.