scholarly journals Effect of Dissolved Oxygen and Inoculum Concentration on Xylose Reductase Production from <i>Candida guilliermondii</i> Using Sugarcane Bagasse Hemicellulosic Hydrolysate

2011 ◽  
Vol 02 (03) ◽  
pp. 235-240 ◽  
Author(s):  
Thais Suzane dos Santos Milessi ◽  
Anuj Kumar Chandel ◽  
Ricardo de Freitas Branco ◽  
Sílvio Silvério da Silva
Keyword(s):  
Dissolved Oxygen ◽  
Sugarcane Bagasse ◽  
Xylose Reductase ◽  
Candida Guilliermondii ◽  
Inoculum Concentration ◽  
Hemicellulosic Hydrolysate

Enhanced Xylitol Production by Precultivation of Candida guilliermondii Cells in Sugarcane Bagasse Hemicellulosic Hydrolysate

2006 ◽  
Vol 53 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Rita C.L.B. Rodrigues ◽  
Luciane Sene ◽  
Gilvane S. Matos ◽  
Inês C. Roberto ◽  
Adalberto Pessoa ◽  
...  
Keyword(s):  
Sugarcane Bagasse ◽  
Candida Guilliermondii ◽  
Xylitol Production ◽  
Hemicellulosic Hydrolysate

Short-Term Adaptation Strategy Improved Xylitol Production by Candida Guilliermondii on Sugarcane Bagasse Hemicellulosic Hydrolysate

2021 ◽  
Author(s):  
Italo de Andrade Bianchini ◽  
Luciane Sene ◽  
Mário Antônio Alves da Cunha ◽  
Maria das Graças de Almeida Felipe
Keyword(s):  
Sugarcane Bagasse ◽  
Adaptation Strategy ◽  
Candida Guilliermondii ◽  
Xylitol Production ◽  
Short Term ◽  
Biotechnological Production ◽  
Toxic Compounds ◽  
Hemicellulosic Hydrolysate ◽  
Beneficial Effects ◽  
Short Term Adaptation

Abstract One of the major bottlenecks of the biotechnological production of xylitol by pentose-fermenting yeasts is the presence of toxic compounds in the hemicellulosic hydrolysates, which inhibit the bioconversion of xylose into xylitol. In this work, short-term adaptation was evaluated as a strategy to minimize the toxicity of the sugarcane bagasse hemicellulosic hydrolysate to Candida guilliermondii FTI 20037. Yeast adaptation improved xylose assimilation as well as xylitol production. The beneficial effects of adaptation were more pronounced in the hydrolysate with higher concentration of toxic compounds, leading to an increase of 62.5% in the xylitol volumetric productivity in comparison to the use of non-adapted cells. In this condition, it was also verified the reduction of glycerol production (about 102%), a by-product formed as consequence of cellular stress, indicating a greater tolerance of adapted cells to the toxicity of hydrolysates. Short-term adaptation proved to be a promising strategy to improve considerably the microbial tolerance and overcome the toxicity of hydrolysates.

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