A randomised comparison of novolimus-eluting and zotarolimus-eluting coronary stents: 9-month follow-up results of the EXCELLA II study

2010 ◽  
Vol 6 (2) ◽  
pp. 195-205 ◽  
Author(s):  
Patrick Serruys ◽  
Scot Garg ◽  
Alexandre Abizaid ◽  
John Ormiston ◽  
Stephan Windecker ◽  
...  
Keyword(s):  
Coronary Stents

Long-Term Follow-Up in Patients With Lost Coronary Stents During Interventional Procedures

2006 ◽  
Vol 98 (3) ◽  
pp. 367-369 ◽  
Author(s):  
Juergen Kammler ◽  
Franz Leisch ◽  
Klaus Kerschner ◽  
Alexander Kypta ◽  
Clemens Steinwender ◽  
...  
Keyword(s):  
Interventional Procedures ◽  
Coronary Stents ◽  
Long Term Follow Up

Long-Term Clinical Follow-up of Sirolimus-Eluting (CYPHER™) Coronary Stents in the Treatment of InStent Restenosis in an Unselected Population

2007 ◽  
Vol 16 (6) ◽  
pp. 440-446 ◽  
Author(s):  
P.E. Ruchin ◽  
D.W.M. Muller ◽  
S.C. Faddy ◽  
D.W. Baron ◽  
P.R. Roy ◽  
...  
Keyword(s):  
Coronary Stents ◽  
Unselected Population

Paclitaxel-eluting stents versus everolimus-eluting coronary stents in a diabetic population: two-year follow-up of the TUXEDO-India trial

2017 ◽  
Vol 13 (10) ◽  
pp. 1194-1201 ◽  
Author(s):  
Upendra Kaul ◽  
Ajit Bhagwat ◽  
Brian Pinto ◽  
Praveen Goel ◽  
Prashant Jagtap ◽  
...  
Keyword(s):  
Coronary Stents ◽  
Diabetic Population

Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique

2007 ◽  
Vol 106 (5) ◽  
pp. 907-911 ◽  
Author(s):  
Seong-Rim Kim ◽  
Min-Woo Baik ◽  
Seung-Hoon Yoo ◽  
Ik-Seong Park ◽  
Sang-Don Kim ◽  
...  
Keyword(s):  
Vertebral Artery ◽  
Stent Placement ◽  
Coronary Stents ◽  
Drug Eluting Stent ◽  
Stent Fracture ◽  
Stent Restenosis ◽  
Stent Strut ◽  
Drug Eluting ◽  
In Stent Restenosis

✓ The authors report two cases of stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery (VA) origin, and describe management of restenosis with the stent-in-stent technique. Two women, one 62 and the other 67 years of age, underwent stent placement in the VA origin to treat symptomatic and angiographically significant stenosis in this vessel. Sirolimus-eluting coronary stents (Cypher) were used in both cases. Four months after placement of the devices, the symptoms recurred. Follow-up angiography performed 5 months after insertion of the devices revealed a transverse stent fracture with separation of the fragments and severe in-stent restenosis in both cases. The restenoses were treated with reinsertion of coronary stents (Cypher and Jostent FlexMaster) by using the stent-in-stent technique. After stent reinsertion, the patients exhibited relief of symptoms. This paper is the first report of fracture in a drug-eluting stent and restenosis after stent placement in the VA origin. Restenosis caused by such a fracture can be managed successfully by performing the stent-in-stent maneuver. The physical properties of metallic devices, stent strut geometry, and anatomical peculiarities of the subclavian artery may be associated with stent fractures. Earlier follow-up angiography studies (within 6 months) are warranted.

Abstract 13819: Is an Adult Familial Hypercholesterolemia, Swine Model Suited to Test Safety and Efficacy of Drug-eluting Coronary Stents?

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Francesca Razzi ◽  
Evelyn Regar ◽  
Jouke Dijkstra ◽  
Karen Witberg ◽  
Jurgen Ligthart ◽  
...  
Keyword(s):  
Familial Hypercholesterolemia ◽  
High Fat Diet ◽  
Coronary Stents ◽  
Plaque Burden ◽  
Swine Model ◽  
Safety And Efficacy ◽  
Drug Eluting ◽  
Oct Imaging ◽  
Novel Drug

Introduction: Safety and efficacy of novel drug-eluting coronary stents (DES) are often preclinically tested using healthy swine coronary models. These only show fibrotic neointima (NI) response, while in humans we also observe uncovered struts and minimal NI thickening. Therefore, healthy swine models only allow limited conclusions. Hypothesis: In an adult familial hypercholesterolemia (FH) swine model, NI healing after coronary DES implantation mimics the range of human NI responses to DES. Methods: Adult FH swine (n=6 French Bretoncelles-Meishan) were given a high fat diet for 12 months to develop coronary atherosclerosis. DES (n=14) were implanted under guidance of OCT at sites of confirmed atherosclerotic plaque. Swine were sacrificed at 28 days follow-up (FU). Serial OCT imaging was performed before, after and 28 days FU. Lumen area, stent area, plaque burden (PB) and NI burden were evaluated for each time point and frame and averaged per stent. PB prior to stenting was evaluated using coronary side branches as references. The percentage uncovered struts at FU was assessed on a strut-by-strut basis. Results: The NI response showed uncovered struts, minimal coverage and fibrotic NI thickening. We found an association between baseline lesion PB and FU findings (Figure). Low PB (<40%) prior to stenting resulted in a thick NI at FU, reminiscent of healthy coronary models. In contrast, high PB (>40%) resulted in thin NI coverage and more uncovered struts at FU, uniquely showing similarities to human responses. Conclusions: In this adult FH swine model, the NI response presents the whole spectrum that is seen in humans, from uncovered struts, to minimal, to fibrotic intimal thickening. Interestingly, pre-existing coronary atherosclerotic PB is negatively associated with NI thickness and strut coverage after DES implantation. This underscores the importance of advanced disease, versus healthy, animal models for safety and efficacy testing of DES.

scholarly journals TCT-457 Paclitaxel - eluting stents vs Everolimus - eluting Coronary Stents in a Diabetic population: 2 Years Follow-up of TUXEDO-India Trial

2016 ◽  
Vol 68 (18) ◽  
pp. B184 ◽  
Author(s):  
Upendra Kaul ◽  
Dr. Rajpal K. Abhaichand ◽  
Tejas Patel ◽  
Darshan Banker ◽  
Atul Abhyankar ◽  
...  
Keyword(s):  
Coronary Stents ◽  
Diabetic Population

Coronary Stents: Evaluation and Follow-up

2017 ◽  
pp. 121-144
Author(s):  
Harvey S. Hecht ◽  
Annapoorna Kini ◽  
Samin Sharma
Keyword(s):  
Coronary Stents
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