Molecular Analysis of Hepatitis B Virus Reverse Transcriptase Domain for Mutations Associated with Viral Resistance in Pakistani Patients

Majid Mahmood; Sdia Jameel; Zia Ur Rahman; Muhammad Asim Anwar

doi:10.4274/vhd.galenos.2021.2021-5-5

Molecular Analysis of Hepatitis B Virus Reverse Transcriptase Domain for Mutations Associated with Viral Resistance in Pakistani Patients

Viral Hepatitis Journal ◽

10.4274/vhd.galenos.2021.2021-5-5 ◽

2021 ◽

Vol 27 (3) ◽

pp. 153-158

Author(s):

Majid Mahmood ◽

Sdia Jameel ◽

Zia Ur Rahman ◽

Muhammad Asim Anwar

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Molecular Analysis ◽

Viral Resistance ◽

Reverse Transcriptase Domain ◽

B Virus

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Novel Natural Mutations in the Hepatitis B Virus Reverse Transcriptase Domain Associated with Hepatocellular Carcinoma

PLoS ONE ◽

10.1371/journal.pone.0094864 ◽

2014 ◽

Vol 9 (5) ◽

pp. e94864 ◽

Cited By ~ 10

Author(s):

Yan Wu ◽

Yu Gan ◽

Fumin Gao ◽

Zhimei Zhao ◽

Yan Jin ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Reverse Transcriptase Domain ◽

B Virus

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Natural variability in surface antigen and reverse transcriptase domain of hepatitis B virus in treatment-naïve chronic HBV-infected Egyptian patients

Virus Research ◽

10.1016/j.virusres.2021.198422 ◽

2021 ◽

pp. 198422

Author(s):

Abdelaziz Elgaml ◽

Mohamed Elegezy ◽

Mohamed El-Mesery ◽

Mohammed El-Mowafy

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Surface Antigen ◽

Natural Variability ◽

Reverse Transcriptase Domain ◽

B Virus ◽

Egyptian Patients ◽

Treatment Naïve ◽

Chronic Hbv

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Variable influence of mutational patterns in reverse-transcriptase domain on replication capacity of hepatitis B virus isolates from antiviral-experienced patients

Clinica Chimica Acta ◽

10.1016/j.cca.2010.10.028 ◽

2011 ◽

Vol 412 (3-4) ◽

pp. 305-313 ◽

Cited By ~ 11

Author(s):

Dong Ji ◽

Yan Liu ◽

Lan-Lan Si ◽

Le Li ◽

Guo-Feng Chen ◽

...

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Replication Capacity ◽

Reverse Transcriptase Domain ◽

B Virus ◽

Variable Influence ◽

Virus Isolates

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Hepatitis B Virus Containing the I233V Mutation in the Polymerase Reverse‐Transcriptase Domain Remains Sensitive to Inhibition by Adefovir

The Journal of Infectious Diseases ◽

10.1086/522521 ◽

2007 ◽

Vol 196 (10) ◽

pp. 1483-1486 ◽

Cited By ~ 26

Author(s):

Maria Curtis ◽

Yuao Zhu ◽

Katyna Borroto‐Esoda

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Reverse Transcriptase Domain ◽

B Virus

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The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir

Antiviral Research ◽

10.1016/j.antiviral.2012.12.007 ◽

2013 ◽

Vol 97 (2) ◽

pp. 93-100 ◽

Cited By ~ 35

Author(s):

Bo Qin ◽

Bettina Budeus ◽

Liang Cao ◽

Chunchen Wu ◽

Yun Wang ◽

...

Keyword(s):

Amino Acid ◽

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Amino Acid Substitutions ◽

Reverse Transcriptase Domain ◽

B Virus

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Expression and Purification of Active Recombinant Reverse Transcriptase Domain of Human HEPATITIS B Virus Polymerase

Journal of Clinical and Experimental Hepatology ◽

10.1016/j.jceh.2014.02.055 ◽

2014 ◽

Vol 4 ◽

pp. S24

Author(s):

Dipendra Raj Pandeya ◽

Ankush Mittal

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Expression And Purification ◽

Reverse Transcriptase Domain ◽

Human Hepatitis ◽

B Virus

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Analysis of resistant mutations in reverse transcriptase domain of hepatitis B virus from patients from Islamabad, Pakistan

Journal of Unexplored Medical Data ◽

10.20517/2572-8180.2017.13 ◽

2017 ◽

Vol 2 (2) ◽

pp. 60

Author(s):

Majid Mahmood ◽

Muhammad Asim Anwar

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Reverse Transcriptase Domain ◽

B Virus

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Faculty Opinions recommendation of Translation of duck hepatitis B virus reverse transcriptase by ribosomal shunting.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021978.247821 ◽

2004 ◽

Author(s):

Don Coen

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Duck Hepatitis B Virus ◽

Duck Hepatitis ◽

B Virus

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Site-specific RNA binding by a hepatitis B virus reverse transcriptase initiates two distinct reactions: RNA packaging and DNA synthesis.

Journal of Virology ◽

10.1128/jvi.68.9.5579-5587.1994 ◽

1994 ◽

Vol 68 (9) ◽

pp. 5579-5587 ◽

Cited By ~ 113

Author(s):

J R Pollack ◽

D Ganem

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Reverse Transcriptase ◽

Dna Synthesis ◽

Rna Binding ◽

Rna Packaging ◽

Site Specific ◽

B Virus

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Hepatitis B virus reverse transcriptase – Target of current antiviral therapy and future drug development

Antiviral Research ◽

10.1016/j.antiviral.2015.09.011 ◽

2015 ◽

Vol 123 ◽

pp. 132-137 ◽

Cited By ~ 45

Author(s):

Daniel N. Clark ◽

Jianming Hu

Keyword(s):

Hepatitis B Virus ◽

Hepatitis B ◽

Drug Development ◽

Reverse Transcriptase ◽

Antiviral Therapy ◽

B Virus ◽

Future Drug

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