The efficiency of various doses of topical isosorbide dinitrate in the treatment of chronic anal fissure and the long-term results: A prospective, randomized and controlled clinical trial

2012 ◽  
Vol 23 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Cuneyt KIRKIL ◽  
Erhan AYGEN ◽  
Osman DOGRU ◽  
Yavuz Selim ILHAN ◽  
Refik AYTEN ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Anal Fissure ◽  
Isosorbide Dinitrate ◽  
Chronic Anal Fissure ◽  
Long Term Results ◽  
Controlled Clinical Trial

scholarly journals The use of ablative lasers in the treatment of facial melasma

2013 ◽  
Vol 88 (2) ◽  
pp. 238-242 ◽  
Author(s):  
Orlando Oliveira de Morais ◽  
Érica Freitas Lima Lemos ◽  
Márcia Carolline dos Santos Sousa ◽  
Ciro Martins Gomes ◽  
Izelda Maria Carvalho Costa ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Short Pulse ◽  
Case Series ◽  
Long Term Results ◽  
Controlled Clinical Trial ◽  
Level Of Evidence ◽  
Short Pulse Duration ◽  
Treatment Regimens ◽  
Postinflammatory Hyperpigmentation

Melasma represents a pigmentary disorder that is difficult to treat. This study aims to broadly review the use of ablative lasers (Er:YAG and CO2) in the treatment of melasma, presenting the level of evidence of studies published to date. A total of 75 patients were enrolled in four case series studies (n=39), one controlled clinical trial (n=6) and one randomized controlled clinical trial (n=30). Studies on the Er:YAG laser showed better results with the use of short square-shaped pulses, which determined low rates of post-inflammatory hyperpigmentation and long-lasting maintenance of results. Likewise, studies on the CO2 laser proved the benefits of short pulse duration along with low-density energy. Post-treatment maintenance with the use of antipigmenting creams was necessary and effective to sustain long-term results. Ablative lasers may represent another useful and effective tool against melasma. Postinflammatory hyperpigmentation and difficulty in sustaining long-term results still represent the main limitations to a broader use of ablative lasers. Based on actual evidence, the use of this technology should be restricted to patients with recalcitrant disease. Further studies will help establish optimal laser parameters and treatment regimens.

Comparison of Glycerine Trinitrate and Botulinum Toxin-A for the Treatment of Chronic Anal Fissure: Long-Term Results

2006 ◽  
Vol 49 (4) ◽  
pp. 427-432 ◽  
Author(s):  
Paola De Nardi ◽  
Enrico Ortolano ◽  
Giovanni Radaelli ◽  
Carlo Staudacher
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Botulinum Toxin A ◽  
Long Term Results ◽  
Toxin A

Surgical versus chemical (botulinum toxin) sphincterotomy for chronic anal fissure: Long-term results of a prospective randomized clinical and manometric study

2005 ◽  
Vol 189 (4) ◽  
pp. 429-434 ◽  
Author(s):  
Antonio Arroyo ◽  
Francisco Pérez ◽  
Pilar Serrano ◽  
Fernando Candela ◽  
Javier Lacueva ◽  
...  
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Long Term Results ◽  
Manometric Study

Long-Term Results of “Chemical Sphincterotomy” for Chronic Anal Fissure: A Prospective Study

2006 ◽  
Vol 49 (6) ◽  
pp. 858-864 ◽  
Author(s):  
Joseph Lysy ◽  
Eran Israeli ◽  
Sharon Levy ◽  
Gloria Rozentzweig ◽  
Nourit Strauss-Liviatan ◽  
...  
Keyword(s):  
Prospective Study ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Long Term Results ◽  
Chemical Sphincterotomy ◽  
A Prospective Study

scholarly journals Effect of botulinum toxin in selected chronic anal fissure patients: long-term results

2012 ◽  
Vol 6 ◽  
pp. 383-385
Author(s):  
Zülfikar Karabulut ◽  
Pașa Doğan ◽  
Gökhan Moray
Keyword(s):  
Botulinum Toxin ◽  
Anal Fissure ◽  
Chronic Anal Fissure ◽  
Long Term Results
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