This article examines research on upper level drug traffickers in the U.S., the UK, Canada, and the Netherlands. Included is an analysis and critique of typologies of drug traffickers and theoretical models of organized crime as they apply to upper level drug networks. Studies of higher level drug trafficking indicate that drug markets represent informal and loosely organized associations of relatively small syndicates or crews of independent drug entrepreneurs. They compete for market share and deal primarily or exclusively with trusted associates chosen from ethnic, kinship, and friendship networks. Most dealers are highly cautious, eschew the use of violence, typically make huge profits, attempt to maintain a low profile, rationalize their conduct as business activity, and operate within geographically niche markets.