scholarly journals ReadiGraft BLX Putty and ReadiGraft Bone Chips in the Treatment of Severe Osteoarthropathy in Hemodialysed Patient.

2020 ◽  
pp. 1-2

Abstract Osteoarticular complications are a major concern in patients treated with long-term hemodialysis, hemofiltration or continuous ambulatory peritoneal dialysis. Uremic chronic patients, treated for long periods of time (≥15 years) with hemodialysis, could develop a new kind of osteoarthropathy due to amyloidosis characterized by abnormal distribution of beta-2 microglobulin (B2M) in joint tissue. Deposits of B2M are responsible for several lesions, clinically evident in different pathologies, such as: carpal tunnel syndrome, spondylarthrosis, and hemodialysis osteoarthropathy.

2020 ◽  
pp. 1-2

Abstract Osteoarticular complications are a major concern in patients treated with long-term hemodialysis, hemofiltration or continuous ambulatory peritoneal dialysis. Uremic chronic patients, treated for long periods of time (≥15 years) with hemodialysis, could develop a new kind of osteoarthropathy due to amyloidosis characterized by abnormal distribution of beta-2 microglobulin (B2M) in joint tissue. Deposits of B2M are responsible for several lesions, clinically evident in different pathologies, such as: carpal tunnel syndrome, spondylarthrosis, and hemodialysis osteoarthropathy.


Medicine ◽  
1989 ◽  
Vol 68 (2) ◽  
pp. 107-115 ◽  
Author(s):  
MICHAEL E. ULLIAN ◽  
WILLIAM S. HAMMOND ◽  
ALLEN C. ALFREY ◽  
ARNOLD SCHULTZ ◽  
BRUCE A. MOLITORIS

1994 ◽  
Vol 17 (11) ◽  
pp. 576-580 ◽  
Author(s):  
V.A. Mioli ◽  
E. Balestra ◽  
L. Bibiano ◽  
S. Dellabella ◽  
E. Fanciulli ◽  
...  

This Study Was Performed In 97 Hemodialysis Patients (85 On Hd And 12 On Capd) To Investigate The Possible Correlation Between B2-M And Hemodialysis-Related Amyloidosis Syndromes (Hra-S); Differences In B2-M And Hra Behavior Between Patients Hemodialysed With Cellulose And Synthetic Membranes Were Also Included In The Present Study. Data Indicate That B2-M Levels Are Not Correlated With Dialysis Length Or With The Type Of Membrane Used For The Dialysis. On The Contrary, In 16 Patients With The Carpal Tunnel Syndrome, A Significant Correlation Was Found Between The Cts, The Dialysis Length And The Type Of Membrane (Greater Incidence With Cellulosic Membranes).


Hand Surgery ◽  
2004 ◽  
Vol 09 (02) ◽  
pp. 165-170 ◽  
Author(s):  
Aya Yoshida ◽  
Ichiro Okutsu ◽  
Ikki Hamanaka ◽  
Tomohide Motomura

In long-term haemodialysis patients, carpal tunnel syndrome (CTS) frequently occurs as a result of amyloid deposition, originating from beta-2 microglobulin, to the flexor retinaculum, paratenons and tendons themselves, which leads to an increase in carpal canal pressure and compression of the median nerve. Surgical procedures can rectify the condition, but continuing maintenance haemodialysis sometimes causes recurrence. We endoscopically operated 1848 hands primarily, 104 recurrent post-endoscopic procedure hands and 130 recurrent post-open procedure hands using the Universal Subcutaneous Endoscope (USE) system, then analysed clinical symptoms and electrophysiological recovery for more than six months post-operatively. The patients were satisfied with the clinical results. Optimal electrophysiological improvements were reported. There were no statistical differences between three groups, except in recovery of touch sensation, which was better in the post-endoscopic group than in the post-open group. There were no complications in this series. Our minimally invasive endoscopic procedure, using the USE system, is safe and effective for primary and recurrent CTS in haemodialysis patients.


2004 ◽  
Vol 58 (4) ◽  
pp. 337-339 ◽  
Author(s):  
A.C.F. Hui ◽  
S.M. Wong ◽  
A. Tang ◽  
V. Mok ◽  
L.K. Hung ◽  
...  

2009 ◽  
Vol 67 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Dante Guilherme Velasco Hardoim ◽  
Guilherme Bueno de Oliveira ◽  
João Aris Kouyoumdjian

OBJECTIVE: To compare a long-term carpal tunnel syndrome (CTS) on nerve conduction studies (NCS) in hands treated non-surgically. METHOD: We retrospectively selected 261 symptomatic CTS hands (166 patients), all of them confirmed by NCS. In all cases, at least 2 NCS were performed in an interval greater than 12 months. Cases with associated polyneuropathy were excluded. NCS parameters for CTS electrodiagnosis included a sensory conduction velocity (SCV) <46.6 m/s (wrist to index finger, 14 cm) and distal motor latency (DML) >4.25 ms (wrist to APB, 8 cm). RESULTS: 92.8% were women; mean age was 49 years (20-76); the mean interval between NCS was 47 months (12-150). In the first exam, the median sensory nerve action potential (SNAP) and the compound action muscular potential were absent in 9.8% and 1.9%, respectively. In the second/last exam, SCV worsened in 54.2%, remained unchanged in 11.6% and improved in 34.2%. SNAP amplitude worsened in 57.7%, remained unchanged in 13.1% and improved in 29.2%. DML worsened in 52.9%, remained unchanged in 7.6% and improved in 39.5%. Overall, NCS parameters worsened in 54.9%, improved in 34.3% and remained unchanged in 10.8%. CONCLUSION: Long-term changing in NCS of CTS hands apparently were not related to clinical symptomatology and could lead to some difficulty in clinical correlation and prognosis. Aging, male gender and absent SNAP were more related to NCS worsening, regardless the mean interval time between the NCS.


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