scholarly journals Recent advances in the management of Ménière's disease

2009 ◽  
Vol 5 (11) ◽  
pp. 324-328
Author(s):  
Helen Sacre ◽  
Rebecca Sherratt ◽  
Han San Au Yung ◽  
Shadaba Ahmed
Keyword(s):  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Evidence Based ◽  
Special Study ◽  
Menière's Disease ◽  
Management Options ◽  
Ménière's Disease

Ménière’s disease is a commonly diagnosed condition. The symptoms of tinnitus, vertigo, hearing loss and fullness in the ear do significantly affect a patient’s quality of life. Currently, the management of Ménière’s has exciting new options available. These options have been reviewed in special study modules by Lancaster University Medical students and provide an excellent evidence-based review of these management options.

Quality-of-Life Outcomes following Surgical Treatment of Ménière’s Disease: A Systematic Review and Meta-analysis

2018 ◽  
Vol 160 (2) ◽  
pp. 232-238 ◽  
Author(s):  
Daniel P. Ballard ◽  
Daniel C. Sukato ◽  
Alisa Timashpolsky ◽  
Seilesh C. Babu ◽  
Richard M. Rosenfeld ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Meta Analysis ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Surgical Treatments

Objective Several surgical interventions are offered to patients with Ménière’s disease (MD) who fail medical management. Although outcomes have historically been reported according to American Academy of Otolaryngology—Head and Neck Surgery guidelines, patient-reported outcome measures (PROMs) are increasingly used to evaluate treatments. This study reviews PROMs used to assess surgical treatments for MD and compares the effect of each intervention based on PROM scores. Data Sources PubMed, EMBASE, CINAHL, and Web of Science. Review Methods This is a systematic review and meta-analysis of English-language studies that reported PROMs for surgical treatments of MD. Two independent investigators assessed study eligibility, rated the quality using Methodological Index for Non-Randomized Studies (MINORS), and abstracted data for comparative analysis. A random-effects model was used for meta-analysis of pooled data. Results Of 148 unique studies identified, 11 satisfied inclusion criteria. The Ménière’s Disease Outcome Questionnaire (MDOQ) was the most commonly used survey. Interventions included intratympanic gentamicin, vestibular nerve section, endolymphatic sac surgery, and labyrinthectomy. Pooled analysis of 8 studies that used the MDOQ instrument demonstrated statistically significant improvements in quality of life but did not identify a difference between destructive and nondestructive procedures. Conclusion Although our review shows significant improvements in PROM scores for both destructive and nondestructive interventions, there was no significant difference noted between treatment types. We cannot draw conclusions regarding the comparative effectiveness of specific interventions, and the results do not account for placebo effects or the natural history of the disease. Further investigation with randomized controlled trials should be considered in future studies.

scholarly journals A randomized control trail on the effectiveness of (Tricyclic antidepressant) Amitriptyline 10 mg bedtime in patients suffering from Meniere’s disease

2018 ◽  
Vol 4 (2) ◽  
pp. 532
Author(s):  
Santhosh Kumar Rajamani ◽  
Pritikanta Sahu
Keyword(s):  
Meniere’S Disease ◽  
Tricyclic Antidepressant ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Randomized Control ◽  
Disease Specific

<p class="abstract"><strong>Background:</strong> Meniere’s disease is one of the most common causes of chronic recurrent vertigo in general population. Meniere’s disease is closely associated with migraine and migrainous vertigo/ vestibular migraine. Amitriptyline has been classically used in management of Vestibular migraine. This randomized control trail examines the effectiveness of (Tricyclic antidepressant) Amitriptyline 10mg bedtime in patients suffering from Meniere’s disease using a Randomized control trial. This was a randomized, double-blinded, placebo-controlled trial, cross over type with a power of 80% at 5% significance level.</p><p class="abstract"><strong>Methods:</strong> One hundred five patients with definite Meniere’s disease were randomized and assigned to either placebo or trial arm. Trial arm were given Amitriptyline 10 mg bedtime and placebo arm were given a generic Vitamin B-complex tablet. Visual analogue score and standard questionnaires were used to assess the improvements in vertigo, imbalance, dizziness and disease-specific quality of life before and after use of Amitriptyline vs. placebo for period of 10 days each.  </p><p class="abstract"><strong>Results:</strong> Amitriptyline 10mg at bedtime (10mg H.S), produces significant improvement in the vertigo in patients suffering from Meniere’s disease compared to placebo. Chronic imbalance and hearing levels are not affected by the use of the above drug regime. Daytime sedation and weight gain are the most troublesome adverse effects of Amitriptyline at 10mg per day dose. No other serious adverse effects were observed in this research.</p><p><strong>Conclusions:</strong> Low dose bedtime Amitriptyline 10mg appears to be safe and produces improvement in vertigo and disease-specific quality of life in Meniere’s disease patients. </p>

scholarly journals STEP TOWARDS UNDERSTANDING THE MYSTERY OF MENIERE’S DISEASE THROUGH AYURVEDA

2021 ◽  
Vol p5 (02) ◽  
pp. 2740-2745
Author(s):  
Anuradha Biserotti ◽  
Prashanth A. S
Keyword(s):  
Hearing Loss ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Drop Attacks ◽  
Inner Ear Disease ◽  
Ménière's Disease

Meniere’s disease is an inner ear disease characterised by episodes of Vertigo, fluctuating sensorineural hearing loss and Tinnitus, associated with Aural pressure Drop attacks (falls without loss of consciousness), Nystagmus, Headache and Nausea. Relapsing nature of the disease hampers the quality of life in patients. And also affects the psychosocial status of the patient. The main pathology occurs as the result of endo-lymphatic system distension, caused by the excessive accumulation of endolymph. This can result from excessive production or reduced absorption of endolymph or both. By knowing the pathology of the Meniere’s disease, clinical features and signs we can consider Karna Nada, Karna Kshweda, (Tinnitus) Badhirya (Hearing Loss) and Bhrama (vertigo) into consideration in which we encounter the vitiation of Karnagata Tarpaka Kapha and Vata. Hence treatment should be aimed at Agni deepana, Vata Anulomana, Vata Kapha Shamana. Nasya Karma, Karna Poorana, Shamana Snehapana, Snigdha Virechana can be employed in the management of Meniere’s Disease.

scholarly journals Impaired Quality of Sleep in Ménière's Disease Patients

2010 ◽  
Vol 06 (05) ◽  
pp. 445-449 ◽  
Author(s):  
Meiho Nakayama ◽  
Motohiko Suzuki ◽  
Akira Inagaki ◽  
Keiji Takemura ◽  
Nobuhiro Watanabe ◽  
...  
Keyword(s):  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Quality Of Sleep ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Impaired Quality

Ménière's Disease Treatment: A Patient-Centered Systematic Review

2015 ◽  
Vol 20 (3) ◽  
pp. 153-165 ◽  
Author(s):  
Mariateresa Tassinari ◽  
Daniele Mandrioli ◽  
Nadia Gaggioli ◽  
Paolo Roberti di Sarsina
Keyword(s):  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Evidence Based ◽  
Menière's Disease ◽  
Patient Centered ◽  
Cochrane Database ◽  
Ménière's Disease ◽  
No Gold Standard

Ménière's disease is a disorder of the inner ear affecting hearing and balance to a varying degree. It is characterized by episodes of vertigo, low-pitched tinnitus, and hearing loss. There is currently no gold standard treatment for Ménière's disease. We conducted a systematic search of the Cochrane Database, as a high-quality source of evidence-based therapies, for reviews on the efficacy of etiological therapy or on Ménière's disease or its symptoms. Following recent positive experiences reported by other research teams, we decided to involve a patients' representative in the assessment and analysis of the evidence retrieved in the literature in order to achieve a more patient-centered evaluation of the therapies. Evidence confirms that an effective treatment of Ménière's disease is still missing, but recent discoveries on the microvascular etiology of Ménière's disease may be assimilated by new evidence-based therapeutic approaches.

How Much Does Dizziness Interfere in Ménière's Disease Patients' Quality of Life?

2004 ◽  
Vol 131 (2) ◽  
pp. P153-P153
Author(s):  
Fernando F Gananca ◽  
Fabiana Cunha ◽  
Flavio Parente Settani ◽  
Anne Marbella ◽  
Katherine B. Myers ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

Functional Results and Quality of Life After Retrosigmoid Vestibular Neurectomy in Patients With Ménière’s Disease

2012 ◽  
Vol 33 (8) ◽  
pp. 1380-1385 ◽  
Author(s):  
Martin Schlegel ◽  
Dominique Vibert ◽  
Sebastian R. Ott ◽  
Rudolf Häusler ◽  
Marco Domenico Caversaccio
Keyword(s):  
Quality Of Life ◽  
Functional Results ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Vestibular Neurectomy ◽  
Ménière's Disease
Sign in / Sign up

Export Citation Format

Share Document