scholarly journals Avoidance of Facial Nerve Injury in Lateral Skull Base Surgery

2011 ◽  
Vol 3 (1) ◽  
pp. 65-70
Author(s):  
Michael E Sughrue
Keyword(s):  
Facial Nerve ◽  
Skull Base Surgery ◽  
Tumor Therapy ◽  
Treatment Strategies ◽  
Tumor Surgery ◽  
New Paradigm ◽  
Nerve Preservation ◽  
Adjuvant Therapies ◽  
Risks And Benefits ◽  
Lateral Skull Base

ABSTRACT In the radiosurgery era, the treatment strategies for vestibular schwannoma have changed at most centers. This new paradigm holds that rational CPA tumor therapy requires balancing often competing goals of therapy, and the associated risks and benefits of different therapies or combination of therapies. The present review discusses this new paradigm and its specific implications for CPA tumor surgery. Inevitably, such a review will focus largely on minimizing facial nerve morbidity, as this is both the most modifiable risk, and the risk that is most reduced with the use of adjuvant therapies, such as stereotactic radiosurgery (like Gamma knife). The facts about facial nerve preservation in CPA tumor surgery will be reviewed, and methods for avoiding facial nerve morbidity will be discussed.

Facial Nerve Preservation During Giant Mandibular Tumor Surgery

2017 ◽  
Vol 28 (2) ◽  
pp. e115-e117
Author(s):  
Yun Zhu ◽  
Wanlin Xu ◽  
Chenping Zhang ◽  
Wenjun Yang
Keyword(s):  
Facial Nerve ◽  
Tumor Surgery ◽  
Nerve Preservation ◽  
Facial Nerve Preservation ◽  
Mandibular Tumor

Facial nerve outcome in lateral skull base surgery for benign lesions

1998 ◽  
Vol 108 (10) ◽  
pp. 1480-1484 ◽  
Author(s):  
Peter G. von Doersten ◽  
C. Gary Jackson ◽  
Spiros Manolidis ◽  
Dennis Pappas ◽  
Michael E. Glasscock
Keyword(s):  
Facial Nerve ◽  
Skull Base ◽  
Skull Base Surgery ◽  
Benign Lesions ◽  
Lateral Skull Base

Increasing Safety in Lateral Skull Base Surgery by Navigation

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Rainer Schmelzeisen ◽  
Marc Metzger
Keyword(s):  
Skull Base ◽  
Skull Base Surgery ◽  
Lateral Skull Base

scholarly journals Fully automated preoperative segmentation of temporal bone structures from clinical CT scans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
C. A. Neves ◽  
E. D. Tran ◽  
I. M. Kessler ◽  
N. H. Blevins
Keyword(s):  
Facial Nerve ◽  
Inner Ear ◽  
Temporal Bone ◽  
Hausdorff Distance ◽  
Sigmoid Sinus ◽  
Ct Scans ◽  
Automated Segmentation ◽  
Dice Coefficient ◽  
Lateral Skull Base ◽  
End To End

AbstractMiddle- and inner-ear surgery is a vital treatment option in hearing loss, infections, and tumors of the lateral skull base. Segmentation of otologic structures from computed tomography (CT) has many potential applications for improving surgical planning but can be an arduous and time-consuming task. We propose an end-to-end solution for the automated segmentation of temporal bone CT using convolutional neural networks (CNN). Using 150 manually segmented CT scans, a comparison of 3 CNN models (AH-Net, U-Net, ResNet) was conducted to compare Dice coefficient, Hausdorff distance, and speed of segmentation of the inner ear, ossicles, facial nerve and sigmoid sinus. Using AH-Net, the Dice coefficient was 0.91 for the inner ear; 0.85 for the ossicles; 0.75 for the facial nerve; and 0.86 for the sigmoid sinus. The average Hausdorff distance was 0.25, 0.21, 0.24 and 0.45 mm, respectively. Blinded experts assessed the accuracy of both techniques, and there was no statistical difference between the ratings for the two methods (p = 0.93). Objective and subjective assessment confirm good correlation between automated segmentation of otologic structures and manual segmentation performed by a specialist. This end-to-end automated segmentation pipeline can help to advance the systematic application of augmented reality, simulation, and automation in otologic procedures.

scholarly journals Cardiooncology—dealing with modern drug treatment, long-term complications, and cancer survivorship

2021 ◽  
Author(s):  
Claudia de Wall ◽  
Johann Bauersachs ◽  
Dominik Berliner
Keyword(s):  
Side Effects ◽  
Checkpoint Inhibitors ◽  
Heart Diseases ◽  
Tumor Therapy ◽  
Treatment Strategies ◽  
Tumor Treatment ◽  
Cardiac Side Effects ◽  
Cardiovascular Side Effects ◽  
Modern Drug

AbstractModern treatment strategies have improved prognosis and survival of patients with malignant diseases. The key components of tumor treatment are conventional chemotherapy, radiotherapy, targeted therapies, and immunotherapy. Cardiovascular side-effects may occur in the early phase of tumor therapy or even decades later. Therefore, knowledge and awareness of acute and long-lasting cardiac side effects of anti-cancer therapies are essential. Cardiotoxicity impairs quality of life and overall survival. The new cardiologic subspecialty ‘cardio-oncology’ deals with the different cardiovascular problems arising from tumor treatment and the relationship between cancer and heart diseases. Early detection and treatment of cardiotoxicity is of crucial importance. A detailed cardiac assessment of patients prior to administration of cardiotoxic agents, during and after treatment should be performed in all patients. The current review focusses on acute and long-term cardiotoxic side effects of classical cytotoxic and selected modern drug treatments such as immune checkpoint inhibitors and discusses strategies for the diagnosis of treatment-related adverse cardiovascular effects in cancer patients.

766 Endoscopic Surgery for Sporadic Vestibular Schwannoma Resection: A Systematic Review of Surgical Outcomes

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
S Chiuta ◽  
S Raza-Knight ◽  
A Alalade
Keyword(s):  
Facial Nerve ◽  
Hearing Preservation ◽  
Extent Of Resection ◽  
Current Data ◽  
Resection Rate ◽  
Eighth Cranial Nerve ◽  
Nerve Preservation ◽  
Microsurgical Resection ◽  
Hearing Outcomes ◽  
Series Report

Abstract Introduction Vestibular schwannomas (VS) are benign intracranial tumours originating from the vestibular division of the eighth cranial nerve. The mainstay of their surgical management is microsurgery, other options are radiotherapy or radiological monitoring. Endoscopy (ES) is becoming widely used in neurosurgery and may have a role in improving visualisation and outcomes by enhancing extent of resection, facial nerve, and hearing preservation in VS resection and describe the postoperative outcomes. Method The review was conducted according to the PRISMA guidelines and yielded 31 studies for inclusion. Systematic searches of literature databases were done for studies where endoscopic-assisted and/or endoscopic resection of VS were reported. Results ES facial nerve preservation rates (median 91.3%, range 39.0 - 100%) were comparable to microsurgical treatment. Hearing outcomes were more variable in ES series and were under-reported. A median gross total resection rate of 97.4% (61.0 - 100%) was achieved in the ES series. Conclusions Current data suggest that ES-assisted resection of sporadic VS is not inferior to microsurgical resection with respect to facial nerve outcomes and extent of resection. However, some ES series report poor hearing outcomes, which are under-reported in the literature.

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