scholarly journals Trophoblastic Diseases

2012 ◽  
Vol 6 (1) ◽  
pp. 27-42 ◽  
Author(s):  
Gino Varga ◽  
Ulrich Honemeyer ◽  
Kazuo Maeda
Keyword(s):  
Blood Flow ◽  
Color Doppler ◽  
Systemic Disease ◽  
Hydatidiform Mole ◽  
Power Doppler ◽  
Doppler Imaging ◽  
Placental Lactogen ◽  
Tumor Blood Flow ◽  
Trophoblastic Tumor ◽  
Trophoblastic Diseases

ABSTRACT Trophoblastic diseases are mainly hydatidiform mole and choriocarcinoma, where the latter is usually the sequela of molar pregnancy and malignant systemic disease with general metastases destructing various tissues and organs till she die. High level urinary hCG, real-time B-mode and color Doppler imaging detect hydatidiform mole in early gestation, postmolar persistent trophoblastic disease is diagnosed by urinary hCG, and treated by prophylactic chemotherapy against choriocarcinoma. Uterine choriocarcinoma and its metastases are diagnosed by hCG and B-mode, color and power Doppler and 3D images detecting rich tumor blood flow. Most choriocarcinoma was effectively treated by primary chemotherapy with methotrexate, etoposide, etc. Until complete remission where hCG is lower than the cut-off level. Placental site trophoblastic tumor (PSTT) and epitheloid trophoblastic tumor (ETT) were low in hCG level and high in human placental lactogen (hPL), and show rich tumor blood flow in color Doppler ultrsound. Nongestational choriocarcinoma is rare and usually chemotherapy resistant. How to cite this article Maeda K, Kurjak A, Varga G, Honemeyer U. Trophoblastic Diseases. Donald School J Ultrasound Obstet Gynecol 2012;6(1):27-42.

scholarly journals High-frequency sonography in the evaluation of nail psoriasis.

2016 ◽  
Vol 18 (3) ◽  
pp. 312 ◽  
Author(s):  
Mihaela Elena Marina ◽  
Carolina Botar Jid ◽  
Sorana Daniela Bolboaca ◽  
Corina Bocsa ◽  
Carmen Mihaela Mihu ◽  
...  
Keyword(s):  
Blood Flow ◽  
High Frequency ◽  
Color Doppler ◽  
Plate Thickness ◽  
Power Doppler ◽  
Psoriasis Patient ◽  
Nail Plate ◽  
Resistance Index ◽  
Doppler Imaging ◽  
Nail Involvement

Aim: To evaluate the morphostructural aspects and nail vascularity in the nail unit of patients with psoriasis, and to evaluate whether there are differences among psoriatic patients with and without nail involvement. Material and methods: Nail plates and nail bed changes, nailfold vessel resistance index (NVRI), power and color Doppler blood flow appearances were investigated in 23 patients with moderate-to-severe psoriasis, with and without nail involvement, and compared to those of 11 healthy participants. Results: Ventral nail plate deposits were present only in psoriasis patients. Irregular or totally fused nail plates and increased nail plate thickness was frequently observed in psoriasis patients compared to controls. NVRI was increased in psoriatic patients’ nails compared to controls (0.62 vs. 0.57, p<0.0001). In the psoriasis patient group there was significant statistical difference in NVRI in patients with nail involvement compared to those without (0.66 vs. 0.55, p<0.0001). Conclusions: High-frequency gray scale sonography provides valuable information regarding morphostructural changes in nail unit structure in patients with psoriasis. Power Doppler imaging enables blood flow assessment in psoriasis nail induced changes.

NUO 2918 Preliminary report on kinetic study of blood flow in prostatic cancer using power doppler imaging

1997 ◽  
Vol 23 ◽  
pp. S61
Author(s):  
Koii Okihara ◽  
Motohiro Knazawa ◽  
Sou Ushijima ◽  
Yutaro Azuma ◽  
Makoto Watanabe ◽  
...  
Keyword(s):  
Blood Flow ◽  
Kinetic Study ◽  
Prostatic Cancer ◽  
Preliminary Report ◽  
Power Doppler ◽  
Doppler Imaging ◽  
Power Doppler Imaging

scholarly journals A Rare Case of Epithelioid Trophoblastic Tumor Presenting as Hematoma of a Caesarean Scar in the Lower Uterine Segment

Medicina ◽  
2021 ◽  
Vol 58 (1) ◽  
pp. 34
Author(s):  
Radomir Aničić ◽  
Aleksandar Rakić ◽  
Rastko Maglić ◽  
Dragutin Sretenović ◽  
Aleksandar Ristić ◽  
...  
Keyword(s):  
Normal Values ◽  
Color Doppler ◽  
Color Doppler Imaging ◽  
Total Abdominal Hysterectomy ◽  
Abdominal Hysterectomy ◽  
Doppler Imaging ◽  
Peripheral Blood Flow ◽  
Trophoblastic Tumor ◽  
Trophoblastic Cells ◽  
Beta Human Chorionic Gonadotropin

Epitheliod trophoblastic tumor (ETT) account for only 1–2% of all the cases of gestational trophoblastic neoplasia (GTN), with a reported mortality rate of 10–24%. ETT is derived from chorionic type intermediate trophoblastic cells, which appears to be the reason for the only slightly elevated βhCG levels in these patients. We present a case of a 42-year-old patient who was admitted to the clinic eight months after Caesarean delivery, for irregular vaginal bleed with normal values of beta-human chorionic gonadotropin (βhCG). A 6 × 5 cm hematoma was evacuated from the isthmic uterine segment during the operation, and the histopathological exam of the tissue surrounding the hematoma revealed ETT. There were no metastatic lesions on the thoracal, abdominal, and pelvic CT. The second ultrasonographic exam revealed tumefaction of 5 cm at the site from the previous surgical procedure. Color Doppler imaging revealed no central nor peripheral blood flow. The patient underwent a total abdominal hysterectomy with bilateral adnexectomy without adjuvant chemotherapy. This appears to be one of the shortest intervals from the anteceded gestational event until the diagnosis of this tumor, along with the absence of the significant ultrasonographic feature of the ETT-peripheral Doppler signal pattern. We underline that, even with normal values of βhCG, irregular vaginal bleeding following the antecedent gestational event should always arouse suspicion of GTN.

Abstract 15137: Vector Flow Mapping is a Novel Useful Technique in Assessing Inertia Force of Late Systolic Aortic Flow and Left Ventricular Early Diastolic Function

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Kazuaki Wakami ◽  
Kenta Hachiya ◽  
Syunsuke Murai ◽  
Tsuyoshi Ito ◽  
Hiroshi Fujita ◽  
...  
Keyword(s):  
Blood Flow ◽  
Time Constant ◽  
Color Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Inertia Force ◽  
Lv Function ◽  
Flow Mapping ◽  
Vector Flow Mapping ◽  
Late Systole

Background: We previously reported that the inertia force (IF) of blood flowing out of left ventricle (LV) during late-systole produces greater LV elastic recoil force and brings faster LV relaxation. Vector flow mapping (VFM TM , Hitachi-Aloka) enables us to see blood flow velocity vectors that are generated from conventional color Doppler imaging data at any phase of cardiac cycle without angle dependency. Using VFM, kinetic energy (KE) of ejecting blood flow during systole at the LV outflow tract (LVOT) can be obtained. Thus, we investigated whether the KE obtained at the LVOT during late systole (KE-ls) had any relations with the IF and invasively obtained LV function parameters. Method: Study subjects were 33 patients who underwent diagnostic cardiac catheterization and echocardiographic examination on the same day. Color Doppler images were acquired in the apical 3-chamber view. The frame rate ranged was from 40 to 51 frames per minute. Data analyses were performed offline using the commercially available software (DAS-RS1 TM, Hitachi-Aloka). A data sampling area was set at the level just below the aortic valve in the LVOT. The KE-ls was computed as the sum of KE values computed in frame by frame basis during late-systole; late-systole was defined as the latter one-third of ejecting time. LV pressure wave was obtained using a catheter-tipped micromanometer, and then, the first derivative of LV pressure (dP/dt) and a time constant τ of LV pressure decay during isovolumic relaxation were calculated. From LV pressure-dP/dt relationships (phase loop), the IF was determined. Results: A significant positive correlation was observed between the KE-ls and the IF (r=0.79, p<0.0001). The log transformed KE-ls had significant correlations with both peak negative dP/dt (r=0.53, p<0.01) and the time constant τ (r=-0.67, p<0.0001). Conclusion: VFM is a new useful technique to see blood flow in the LV chamber. Noninvasively obtained KE-ls using VFM, which may be a noninvasive surrogate for the IF, has significant correlations with the parameters of LV relaxation.

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