scholarly journals Fetal Anatomical Survey during Second Trimester Screening Examination

Author(s):  
Armando Pintucci ◽  
Vincenzo Pinto ◽  
Luca Di Cagno ◽  
Angela Cristina Rossi ◽  
Vincenzo D'Addario

ABSTRACT Screening for fetal malformations is one of the main aims of ultrasonography during pregnancy. In most cases fetal anomalies occur as an unexpected event in not at risk patients: For this reason the only way to rule out congenital malformations is to screen every pregnant patient with a systematic evaluation of the fetal anatomy. The ultrasonic screening of fetal malformations has to be based on a single examination that has to be planned at a gestational age which is advanced enough to visualize most fetal anomalies and early enough to plan further diagnostic tests and allow the termination of pregnancy in the case of severe malformation. The gestational age that constitutes the best compromise between the need of an early diagnosis and the natural history of most congenital malformations is the period ranging from 19 to 21 weeks of gestation. This ultrasonic examination is known as ‘fetal anomaly scan’ or ‘fetal morphology scan’. Some scientific societies suggest guidelines for the optimal performance of such examination. In this paper the minimal standards for an accurate ‘fetal morphology scan’ will be described. How to cite this article D'Addario V, Pinto V, Di Cagno L, Pintucci A, Rossi AC. Fetal Anatomical Survey during Second Trimester Screening Examination. Donald School J Ultrasound Obstet Gynecol 2012;6(1):43-54.

2017 ◽  
Vol 45 (7) ◽  
Author(s):  
Karolina Bartkute ◽  
Dalia Balsyte ◽  
Josef Wisser ◽  
Juozas Kurmanavicius

AbstractAim:The aim of this study was to evaluate the predictive value of α-fetoprotein in maternal serum (MS-AFP) as a marker for diverse pregnancy outcomes.Methods:The study was based on pregnancy and delivery data from 5520 women between 1999 and 2014 at University Hospital of Zurich (UHZ). Inclusion criteria: both MS-AFP and pregnancy outcome were known for the same pregnancy. Pregnancy outcomes and characteristics such as fetal malformation, intrauterine fetal death (IUFD) and intrauterine growth retardation as well as maternal age, weight before pregnancy, gestational age (GA) at delivery, newborn weight, length and head circumference were analyzed with respect to the MS-AFP value. MS-AFP value was categorized into three groups: elevated MS-AFP>2.5 multiples of the median (MoM), normal 0.5–2.49 MoM and decreased <0.5 MoM.Results:Newborn weight (g) and length (cm) were significantly lower in the elevated MS-AFP (P<0.001) group, and infants had 1 week lower GA at delivery (P<0.05). In the group of elevated MS-AFP (n=46), 26.1% of pregnancies were significantly related to adverse pregnancy outcomes, such as fetal malformations, fetuses small for gestational age (SGA) and IUFD. Adverse pregnancy outcomes of 5.6% were registered in the group of normal MS-AFP and 7.3% in the group of low MS-AFP (P<0.05).Conclusion:MS-AFP level in the second trimester is still an important indicator of fetal surface malformations; however, ultrasound still outweighs as a screening method. Nevertheless, pregnant women with elevated MS-AFP values and with no sonographically detected fetal malformations should additionally receive the third trimester ultrasound examination to exclude other possible complications of pregnancy.


2013 ◽  
Vol 26 (16) ◽  
pp. 1635-1640 ◽  
Author(s):  
Nieves L. González González ◽  
Walter Plasencia ◽  
Enrique González Dávila ◽  
Erika Padrón ◽  
Gian C. di Renzo ◽  
...  

1998 ◽  
Vol 847 (1 ULTRASOUND SC) ◽  
pp. 200-209 ◽  
Author(s):  
GIUSEPPINA D'OTTAVIO ◽  
GIAMPAOLO MANDRUZZATO ◽  
YORAM J. MEIR ◽  
MARIA ANGELA RUSTICO ◽  
LEO FISCHER-TAMARO ◽  
...  

2012 ◽  
Vol 40 (S1) ◽  
pp. 264-264
Author(s):  
E. Colantuono ◽  
F. D'Antonio ◽  
M. Recchi ◽  
L. Marrone ◽  
B. Matarrelli ◽  
...  

2014 ◽  
Vol 34 (11) ◽  
pp. 1099-1105 ◽  
Author(s):  
D. G. Iliescu ◽  
M. L. Cara ◽  
S. Tudorache ◽  
P. Antsaklis ◽  
L. V. Novac ◽  
...  

2021 ◽  
Vol 58 (S1) ◽  
pp. 175-175
Author(s):  
B. Deloison ◽  
G. Benoit ◽  
C. Bernabe Dupont ◽  
A. Sabine ◽  
F. Jacquemard ◽  
...  

2020 ◽  
Author(s):  
AYSE OZBAN

Abstract Objective: This study aims to determine whether it is possible to predict preeclampsia by comparing postpartum results and test results of the pregnant women diagnosed with preeclampsia, whose first and/or second trimester screening tests were accessible, and to demonstrate the predictability of severity and week of onset.Background: 204 patients underwent renal transplantation in our center and 84 of them were female. Five of our patients (one of them had two births) gave birth to a total of 6 pregnancies.Method: 135 patients were diagnosed with preeclampsia and their first and/or second trimester screening tests were accessible, and 366 control participants gave birth to a healthy baby between 37-41 weeks after standard follow-up period for pregnancy and their screening tests were also accessible.Results: The study results show that the first trimester maternal serum PAPP-A level is significantly low in preeclamptic pregnant women, and that the second trimester maternal serum AFP and hCG levels are significantly high and uE3 levels are significantly low The results also suggest that the first and second trimester Down syndrome biochemical markers can be used in preeclampsia screening.Conclusion: Among these markers, uE3 is the parameter which affects the possibility of preeclampsia the most. However, the first and second trimester Down syndrome biochemical markers are not effective in predicting the severity and onset week of preeclampsia.


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