scholarly journals Estimation of Median Values of Second Trimester Screening Test for Our Hospital

Author(s):  
Muzaffer Katar
2018 ◽  
Vol 24 (2) ◽  
pp. 71 ◽  
Author(s):  
Umit Gorkem ◽  
Ayse Semra Gureser ◽  
Cihan Togrul ◽  
Djursun Karasartova ◽  
Tayfun Gungor ◽  
...  

<p><strong>Objective:</strong> With apoptosis being critical for the development and homeostasis of placental tissues, it is possible to hypothesize that accelerated trophoblastic apoptosis during pregnancy may result in a partial loss of trophoblastic activity or trophoblastic cell mass, and ultimately may alter the second-trimester screening test parameters. Thus, this study was conducted to investigate the influence of maternal toxoplasmosis on second-trimester aneuploidy screening tests.<br /><strong></strong></p><p><strong>Study Design:</strong> This retrospective study was conducted with 552 pregnant women admitted to our University Hospital. The demographic data such as maternal age and weight; and the main parameters of second-trimester aneuploidy screening test including maternal serum alpha-fetoprotein, unconjugated estriol (uE3) and human chorionic gonadotropin were analyzed with the comparison of their Toxoplasma immunoglobulin serology results.</p><p><strong>Results:</strong> The mean age of the pregnant women was 27.6 (17.0 - 43.0) years, and the mean maternal weight was estimated at 65.0 (40.0 - 120.0) kg. The pregnant women with positive Toxoplasma IgG antibody had a higher mean maternal age than those with negative Toxoplasma IgG antibody (p&lt; 0.0001). No significant difference for the concentrations and MoM values of second-trimester screening test parameters in women with Toxoplasma IgM and IgG antibodies was observed (p&gt; 0.05, for all).</p><p><strong>Conclusion:</strong> Although IgG-seropositivity of toxoplasmosis may lead to an accelerated trophoblastic apoptosis during pregnancy, there is no significant influence on the second-trimester screening test results. There was no data regarding the unaffected population whom used for calculation of MoM, if they</p>


2012 ◽  
Vol 40 (S1) ◽  
pp. 264-264
Author(s):  
E. Colantuono ◽  
F. D'Antonio ◽  
M. Recchi ◽  
L. Marrone ◽  
B. Matarrelli ◽  
...  

2014 ◽  
Vol 34 (11) ◽  
pp. 1099-1105 ◽  
Author(s):  
D. G. Iliescu ◽  
M. L. Cara ◽  
S. Tudorache ◽  
P. Antsaklis ◽  
L. V. Novac ◽  
...  

2021 ◽  
Vol 58 (S1) ◽  
pp. 175-175
Author(s):  
B. Deloison ◽  
G. Benoit ◽  
C. Bernabe Dupont ◽  
A. Sabine ◽  
F. Jacquemard ◽  
...  

2020 ◽  
Author(s):  
AYSE OZBAN

Abstract Objective: This study aims to determine whether it is possible to predict preeclampsia by comparing postpartum results and test results of the pregnant women diagnosed with preeclampsia, whose first and/or second trimester screening tests were accessible, and to demonstrate the predictability of severity and week of onset.Background: 204 patients underwent renal transplantation in our center and 84 of them were female. Five of our patients (one of them had two births) gave birth to a total of 6 pregnancies.Method: 135 patients were diagnosed with preeclampsia and their first and/or second trimester screening tests were accessible, and 366 control participants gave birth to a healthy baby between 37-41 weeks after standard follow-up period for pregnancy and their screening tests were also accessible.Results: The study results show that the first trimester maternal serum PAPP-A level is significantly low in preeclamptic pregnant women, and that the second trimester maternal serum AFP and hCG levels are significantly high and uE3 levels are significantly low The results also suggest that the first and second trimester Down syndrome biochemical markers can be used in preeclampsia screening.Conclusion: Among these markers, uE3 is the parameter which affects the possibility of preeclampsia the most. However, the first and second trimester Down syndrome biochemical markers are not effective in predicting the severity and onset week of preeclampsia.


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