scholarly journals Saccharide Effect on the Lower Critical Solution Temperature of Poly(organophosphazenes) with Methoxy-poly(ethylene glycol) and Amino Acid Esters as Side Groups

2003 ◽  
Vol 24 (7) ◽  
pp. 901-905 ◽  
Keyword(s):  
Amino Acid ◽  
Ethylene Glycol ◽  
Lower Critical Solution Temperature ◽  
Solution Temperature ◽  
Amino Acid Esters ◽  
Poly Ethylene Glycol ◽  
Critical Solution Temperature ◽  
Poly Ethylene ◽  
Acid Esters

Structural and Thermosensitive Properties of Cyclotriphosphazenes with Poly(ethylene glycol) and Amino Acid Esters as Side Groups

2001 ◽  
Vol 34 (21) ◽  
pp. 7565-7569 ◽  
Author(s):  
Sang Beom Lee ◽  
Soo-Chang Song ◽  
Jung-Il Jin ◽  
Youn Soo Sohn
Keyword(s):  
Amino Acid ◽  
Ethylene Glycol ◽  
Amino Acid Esters ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Acid Esters

Synthesis and Property of Photo- and Temperature- Dual-Responsive Amphiphilic Block Copolymers

2009 ◽  
Vol 87-88 ◽  
pp. 47-51
Author(s):  
Xin De Tang ◽  
Nian Feng Han ◽  
De Jie Zhou
Keyword(s):  
Block Copolymers ◽  
Ethylene Glycol ◽  
Drug Carrier ◽  
Amphiphilic Block Copolymers ◽  
Solution Temperature ◽  
Poly Ethylene Glycol ◽  
Critical Solution Temperature ◽  
Dual Responsive ◽  
Hexyl Methacrylate ◽  
Poly Ethylene

Photo- and temperature-responsive amphiphilic block copolymers, poly(ethylene glycol)-b-poly{(N-isopropylacrylamide-co-6-[4-(4-methoxyphenylazo)phenoxy]hexyl methacrylate), denoed as PEO-b-P(NIPAM-co-MAZO), were designed and synthesized by atom transfer radical polymerization (ATRP). The macroinitiator based on poly(ethylene glycol) (PEG, Mn = 2000 Da) was utilized to initiate the copolymerization of N-isopropylacrylamide (NIPAM) and 6-[4-(4-methoxyphenylazo)phenoxy]hexyl methacrylate (MAZO). The resultant copolymers, combining photo-responsive moieties with thermal-responsive moieties, possess photo- and temperature- dual-responsive property, among of which, PNIPAM shows lower critical solution temperature (LCST) and PMAZO exhibits reversible trans-cis isomerization under UV/vis irradiation. In selective solution they can form selective micro-tunnel with excellent controlled release, and can be used as drug carrier and controllable membrane.

Reversibly cross-linked poly(ethylene glycol)–poly(amino acid)s copolymer micelles: a promising approach to overcome the extracellular stability versus intracellular drug release challenge

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20025-20034 ◽  
Author(s):  
Yuling Li ◽  
Sai Wang ◽  
Dandan Zhu ◽  
Yuling Shen ◽  
Baixiang Du ◽  
...  
Keyword(s):  
Amino Acid ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Lipoic Acid ◽  
Triblock Copolymer ◽  
Intracellular Delivery ◽  
Poly Ethylene Glycol ◽  
Copolymer Micelles ◽  
Poly Ethylene ◽  
Copolymer Poly

Reversibly shell cross-linked micelles based on a lipoic acid (LA) decorated triblock copolymer poly(ethylene glycol)-b-poly(γ-benzyl-l-glutamate)-b-poly(l-phenylalanine) have been developed for efficient intracellular delivery of DOX.

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