scholarly journals Arborizing Vessels on Dermoscopy in Various Skin Diseases Other Than Basal Cell Carcinoma

2017 ◽  
Vol 29 (3) ◽  
pp. 288 ◽  
Author(s):  
Hyunju Jin ◽  
Min-Young Yang ◽  
Jeong-Min Kim ◽  
Gun-Wook Kim ◽  
Hoon-Soo Kim ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Diseases

Viral and Nonviral Uses of Imiquimod: A Review

2004 ◽  
Vol 8 (5) ◽  
pp. 338-352 ◽  
Author(s):  
Aditya K. Gupta ◽  
Andrea M. Cherman ◽  
Stephen K. Tyring
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Diseases ◽  
Interleukin 12 ◽  
Antitumor Effects ◽  
Skin Reactions ◽  
Local Skin ◽  
Actinic Keratoses ◽  
Skin Conditions

Background: Imiquimod is a topical immunomodulator that is indicated for the treatment of external genital and perianal warts. This drug has been recently approved for the treatment of actinic keratoses and superficial basal cell carcinoma. There is a growing body of evidence for its effectiveness in treating a variety of other skin conditions. Objective: This review examines the role of imiquimod 5% cream in the treatment of skin diseases such as actinic keratoses, basal cell carcinoma, Bowen's disease, lentigo maligna, and extramammary Paget's disease. Methods: Published literature containing the words “Imiquimod” or “Aldara” was reviewed and summarized. Results: This agent has demonstrated indirect antiviral and antitumor effects in animal models. Although the exact mechanism of action is unknown, imiquimod is an agonist for toll-like receptor (TLR) 7 and is thought to act by inducing cytokines, such as interferon alpha (IFN-α), interleukin-12 (IL-12), and tumor necrosis factor alpha (TNF-α). These cytokines trigger the immune system to recognize the presence of a viral infection or tumor and the associated lesion is ultimately eradicated. Side effects are generally well tolerated with local skin reactions reported most frequently. Conclusion: Imiquimod has been shown to be a safe and effective treatment for a variety of skin conditions.

scholarly journals Assistant Diagnosis of Basal Cell Carcinoma and Seborrheic Keratosis in Chinese Population Using Convolutional Neural Network

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Kai Huang ◽  
Xiaoyu He ◽  
Zhentao Jin ◽  
Lisha Wu ◽  
Xinyu Zhao ◽  
...  
Keyword(s):  
Neural Network ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Chinese Population ◽  
Skin Diseases ◽  
Area Under The Curve ◽  
Seborrheic Keratosis ◽  
Clinical Images ◽  
Learning Techniques

Objectives. To evaluate CNN models’ performance of identifying the clinical images of basal cell carcinoma (BCC) and seborrheic keratosis (SK) and to compare their performance with that of dermatologists. Methods. We constructed a Chinese skin diseases dataset which includes 1456 BCC and 1843 SK clinical images and the corresponding medical history. We evaluated the performance using four mainstream CNN structures and transfer learning techniques. We explored the interpretability of the CNN model and compared its performance with that of 21 dermatologists. Results. The fine-tuned InceptionResNetV2 achieved the best performance, with an accuracy and area under the curve of 0.855 and 0.919, respectively. Further experimental results suggested that the CNN model was not only interpretable but also had a performance comparable to that of dermatologists. Conclusions. This study is the first on the assistant diagnosis of BCC and SK based on the proposed dataset. The promising results suggested that CNN model’s performance was comparable to that of expert dermatologists.

scholarly journals Analysis of 14-3-3σ expression in hyperproliferative skin diseases reveals selective loss associated with CpG-methylation in basal cell carcinoma

Oncogene ◽  
2003 ◽  
Vol 22 (35) ◽  
pp. 5519-5524 ◽  
Author(s):  
Dimitri Lodygin ◽  
Amir S Yazdi ◽  
Christian A Sander ◽  
Thomas Herzinger ◽  
Heiko Hermeking
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Diseases ◽  
Cpg Methylation ◽  
Selective Loss

Genetic skin diseases predisposing to basal cell carcinoma

2012 ◽  
Vol 22 (3) ◽  
pp. 299-309 ◽  
Author(s):  
Marco Castori ◽  
Aldo Morrone ◽  
Jean Kanitakis ◽  
Paola Grammatico
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Diseases

scholarly journals Histopathological spectrum of skin diseases in a tertiary skin health and referral centre

2019 ◽  
Vol 9 (1) ◽  
pp. 1434-1440 ◽  
Author(s):  
Ram Chandra Adhikari ◽  
Mahesh Shah ◽  
Anjani Kumar Jha
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Skin Diseases ◽  
Fungal Infections ◽  
Melanocytic Nevus ◽  
Skin Tumors ◽  
Referral Centre ◽  
Common Skin ◽  
Frequent Site

Background: Skin diseases are very much prevalent in the developing countries. The pattern of skin diseases varies from country to country and even region to region within a country. The histological diagnosis is used by clinicians to aid in the management of patients & most appropriate clinical interventions. Materials and methods: The study included a total of 1040 skin biopsies from January 2016 to December 2018 in the department of pathology, DI skin health and referral centre, Kathmandu, Nepal. Results: The majority of the patients were in the age group of 31-40 years. The most common skin disease is non-infectious vesicobullous and vesicopustular disease (28.6%), followed by non-infectious erythematous papular and squamous disease (25.9%). The most common vesicobullous disease is spongiotic dermatitis (84.8%). Erythema dyschromicum perstans (31.8%) is the commonest non-infectious erythematous papular and squamous disease. The most common microbial disease is fungal infection, followed by leprosy. Among the neoplastic diseases of skin, tumors of epidermis are commonest diseases and the most common epidermal tumor is basal cell carcinoma. The commonest tumor of skin is melanocytic nevus.  The most frequent site is upper extremities. Conclusions: Eczema is predominating non-infectious vesicobullous and vesicopustular disease.  A relatively higher, prevalence of fungal infections was observed. Basal cell carcinoma is the commonest epidermal tumor and melanocytic nevus is commonest of all skin tumors.

Ultrastructure of Mouse Basal Cell Carcinoma Exhibiting Sebaceous Differentiation

1980 ◽  
Vol 38 ◽  
pp. 738-739
Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Topical Application ◽  
Basal Cell ◽  
Sebaceous Gland ◽  
Rats And Mice ◽  
Mixed Tumors

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.

Basal cell carcinoma of the nail bed in a Korean woman

2000 ◽  
Vol 39 (5) ◽  
pp. 397-398 ◽  
Author(s):  
Hyoung-Joo Kim ◽  
Youn-Soo Kim ◽  
Ki-Beom Suhr ◽  
Tae-Young Yoon ◽  
Jeung-Hoon Lee ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Korean Woman ◽  
Nail Bed

Basal cell carcinoma at the base of cutaneous horn (cornu cutaneum)

1971 ◽  
Vol 104 (1) ◽  
pp. 97-98 ◽  
Author(s):  
M. Sandbank
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Cutaneous Horn ◽  
Cornu Cutaneum

Granular cell basal cell carcinoma. A distinct histopathologic entity

1979 ◽  
Vol 115 (9) ◽  
pp. 1064-1067 ◽  
Author(s):  
R. J. Barr
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Granular Cell
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