RENAL TRANSPLANT RELATED ANAESTHESIA EXPERIENCE, CONSIDERATIONS AND PRACTICE OVERVIEW OF AFIU, RAWALPINDI

Objective: To describe our experience of renal transplant operations in our institute. Study Design: Prospective observational study. Place and Duration of Study: Department of Anaesthesiology, Armed Forces Institute of Urology, Rawalpindi, from Sep 2016 to Sep 2019. Methodology: A total of 170 living related renal transplants were included in this study. Soda bicarbonate was given intra operatively to recipients according to arterial blood gas results. Blood transfusion was done where indicated. Results: Out of 340 (100 %) patients, 170 (50%) were living related donors and 170 (50%) were transplant recipients General anesthesia was the technique of choice. Three (1.76%) recipients out of 170 were awaked from anesthesia and postponed. Five (2.94%) patients were reopened on the same evening and 2 (1.17%) patients had transplant nephrectomy over a period 1 month. Soda bicarbonate was given to 143 (84.1%) and blood transfusion in 4 (2.35%) transplant recipients where as one patient had anaphylaxis intra-operatively. Conclusion: Living related kidney transplant is the standard transplant procedure in our institute because of non-availability of cadaveric donor. It’s now time that deceased donor program be started in Pakistan due to increased cases of renal failure and decreased living donors.

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Quality of life and emotional responses in cadaver and living related renal transplant recipients

Nephrology Dialysis Transplantation ◽

10.1093/ndt/17.12.2204 ◽

2002 ◽

Vol 17 (12) ◽

pp. 2204-2211 ◽

Cited By ~ 68

Author(s):

K. Griva

Keyword(s):

Quality Of Life ◽

Renal Transplant ◽

Emotional Responses ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Living Related

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Effects of Rituximab on the Development of Viral and Fungal Infections in Renal Transplant Recipients

ISRN Transplantation ◽

10.5402/2013/819025 ◽

2013 ◽

Vol 2013 ◽

pp. 1-8 ◽

Cited By ~ 6

Author(s):

Samir J. Patel ◽

Jennifer M. Devos ◽

Richard J. Knight ◽

Kyle L. Dawson ◽

Wadi N. Suki ◽

...

Keyword(s):

Renal Transplant ◽

Odds Ratio ◽

Viral Infections ◽

Fungal Infections ◽

Graft Function ◽

Deceased Donor ◽

Infectious Complications ◽

Renal Transplant Recipients ◽

Transplant Recipients ◽

Kidney Transplant Recipients

Background. Rituximab is becoming increasingly utilized in renal transplant recipients; however, its association with infections remains unclear. Methods. We reviewed the incidence of viral and fungal infections in kidney transplant recipients treated with () or without () rituximab (RTX) in addition to standard immunosuppression. Results. Infections occurred in 134 (30%) patients, with a greater proportion in RTX versus no RTX patients (47% versus 28%; ). Viral infections occurred in 44% and 27% of RTX and no RTX patients, respectively (). This was largely driven by the frequency of BK viremia and noncytomegalovirus/non-BK viruses in RTX patients (27% versus 13% () and 15% versus 2% (), resp.). Fungal infections also occurred more often in RTX patients (11% versus 3 %; ). Multivariate analysis revealed deceased donor recipient (odds ratio = 2.5; ) and rituximab exposure (odds ratio = 2.2; ) as independent risk factors for infection. Older patients, deceased donor recipients, those on dialysis longer, and those with delayed graft function tended to be at a greater risk for infections following rituximab. Conclusions. Rituximab is associated with an increased incidence of viral and fungal infections in kidney transplantation. Additional preventative measures and/or monitoring infectious complications may be warranted in those receiving rituximab.

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