scholarly journals EPISODES OF HEARTBURN AND BLOATING IN MEDICAL PRACTICE

2021 ◽  
Author(s):  
VAZHA GVANTSELADZE ◽  
NANA GNANTSELADZE
Keyword(s):  
Quality Of Life ◽  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Gastric Ulcers ◽  
Ability To Work ◽  
Ulcer Disease ◽  
Impaired Ability ◽  
Georgian Population

The aim of the study was to study the frequency and nature of episodes of heartburn and bloating in patients with duodenal and gastric ulcers in the Georgian population, considering the histomorphological and morphometric changes of the gastric mucosa and the parameters of gastric secretion. At the same time, we were interested in analyzing patients' anamnesis before being hospitalized for the last 2 months. The analysis of the material showed that incidence of heartburn episodes in the Georgian population is clearly higher in patients with peptic ulcer disease 12 - (79.9%) than in patients with gastric ulcer (9 - 31.9%). Episodes of heartburn in these patients are characterized not only by increasing of rate (more than 50 episodes), both day and night, but the intensity and duration (which is due to abnormal gastroesophageal reflux). This is a high risk for the occurrence of heartburn episodes. As for bloating, it was detected in patients with duodenal ulcer (11–26.2%), in gastric ulcer 11– (32.9%). The main pathogenetic aspects of heartburn episodes were found to be diffuse fundal glands hyperplasia and high acidity (duodenal ulcer and pyloric anterior ulcer). It was also found that a large percentage of patients were not treated properly, leading to impaired ability to work and changes in quality of life and disease progression.

Peptic Ulcer Diseases

2018 ◽  
Author(s):  
Edward A Lew
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Clinical Manifestations ◽  
Muscularis Propria ◽  
Gastric Ulcers ◽  
Peptic Ulcers ◽  
Ulcer Disease ◽  
H Pylori

Peptic ulcers are defects or breaks in the inner lining of the gastrointestinal (GI) tract. Although the pathogenesis is multifactorial they tend to arise when there is an imbalance between protective and aggressive factors, such as when GI mucosal defense mechanisms are impaired in the presence of gastric acid and pepsin. Peptic ulcers extend through the mucosa and the muscularis mucosae, a thin layer of smooth muscle separating the mucosa from the deeper submucosa, muscularis propria, and serosa. Peptic ulcer disease affects up to 10% of men and 4% of women in Western countries at some time in their lives. This chapter discusses the pathogenesis of peptic ulcer disease and the etiologic contribution of Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, and gastrinoma or other hypersecretory states. Also addressed are rare and unusual causes for ulcers and GI bleeding. A section on the diagnosis of peptic ulcers discusses clinical manifestations, physical examination findings, laboratory and imaging studies, and surgical diagnosis. Differential diagnosis is also reviewed. Tests to establish the etiology of peptic ulcer disease include endoscopy, quantitative serologic tests, the urea breath test, and the fecal antigen test. Discussed separately are treatments for uncomplicated duodenal ulcers, uncomplicated gastric ulcers, intractable duodenal or gastric ulcers, complicated peptic ulcers (bleeding ulcers, acute stress ulcers, perforated ulcers, obstructing ulcers, fistulizing ulcers, and Cameron ulcers), H. pylori ulcers, and gastric cancer. Figures illustrate the etiopathogenesis of peptic ulcers, prevalence of H. pylori infection in duodenal and gastric ulcer patients compared with normal controls, the approach to a patient with new and undiagnosed ulcerlike symptoms refractory to antisecretory therapy, an upper GI series showing an uncomplicated duodenal ulcer, a chest x-ray showing pneumoperitoneum from a perforated duodenal ulcer, gastric biopsy samples showing H. pylori organisms, and the approach to treatment and follow-up in patients with either complicated or uncomplicated duodenal or gastric ulcer. Tables list differential diagnoses of peptic ulcer disease, commonly used regimens to eradicate H. pylori, additional antimicrobial agents with activity against H. pylori, and FDA-approved antisecretory drugs for active peptic ulcer disease. This chapter contains 76 references.

Peptic Ulcer Diseases

2020 ◽  
Author(s):  
Edward A Lew
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Clinical Manifestations ◽  
Muscularis Propria ◽  
Gastric Ulcers ◽  
Peptic Ulcers ◽  
Ulcer Disease ◽  
H Pylori

Peptic ulcers are defects or breaks in the inner lining of the gastrointestinal (GI) tract. Although the pathogenesis is multifactorial they tend to arise when there is an imbalance between protective and aggressive factors, such as when GI mucosal defense mechanisms are impaired in the presence of gastric acid and pepsin. Peptic ulcers extend through the mucosa and the muscularis mucosae, a thin layer of smooth muscle separating the mucosa from the deeper submucosa, muscularis propria, and serosa. Peptic ulcer disease affects up to 10% of men and 4% of women in Western countries at some time in their lives. This chapter discusses the pathogenesis of peptic ulcer disease and the etiologic contribution of Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs, and gastrinoma or other hypersecretory states. Also addressed are rare and unusual causes for ulcers and GI bleeding. A section on the diagnosis of peptic ulcers discusses clinical manifestations, physical examination findings, laboratory and imaging studies, and surgical diagnosis. Differential diagnosis is also reviewed. Tests to establish the etiology of peptic ulcer disease include endoscopy, quantitative serologic tests, the urea breath test, and the fecal antigen test. Discussed separately are treatments for uncomplicated duodenal ulcers, uncomplicated gastric ulcers, intractable duodenal or gastric ulcers, complicated peptic ulcers (bleeding ulcers, acute stress ulcers, perforated ulcers, obstructing ulcers, fistulizing ulcers, and Cameron ulcers), H. pylori ulcers, and gastric cancer. Figures illustrate the etiopathogenesis of peptic ulcers, prevalence of H. pylori infection in duodenal and gastric ulcer patients compared with normal controls, the approach to a patient with new and undiagnosed ulcerlike symptoms refractory to antisecretory therapy, an upper GI series showing an uncomplicated duodenal ulcer, a chest x-ray showing pneumoperitoneum from a perforated duodenal ulcer, gastric biopsy samples showing H. pylori organisms, and the approach to treatment and follow-up in patients with either complicated or uncomplicated duodenal or gastric ulcer. Tables list differential diagnoses of peptic ulcer disease, commonly used regimens to eradicate H. pylori, additional antimicrobial agents with activity against H. pylori, and FDA-approved antisecretory drugs for active peptic ulcer disease. This chapter contains 5 figures, 6 tables and 78 references.

scholarly journals Current status of peptic ulcer disease in Port Harcourt metropolis, Nigeria

2020 ◽  
Vol 20 (3) ◽  
pp. 1446-1451
Author(s):  
Emeka Ray-Offor ◽  
Kalanne Ada Opusunju
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Blood Group ◽  
Hospital Admissions ◽  
Current Status ◽  
Gastric Ulcers ◽  
Ulcer Disease ◽  
Port Harcourt

Background: Epidemiological studies on peptic ulcer disease (PUD) have shown a recent decrease in hospital admissions in Western countries. Objective: This paper aimed to study the current status and risk factors of PUD in a Nigerian metropolis. Methods: A cross-sectional study of symptomatic patients at upper gastrointestinal (GI) endoscopy diagnosed with PUD from February 2014 to September 2019 at a referral endoscopy facility in Port Harcourt, Niger delta region of Nigeria. The variables studied included demographics, symptoms and duration, blood group, chronic non-steroidal anti-inflammatory (NSAID) use, smoking, endoscopic and histology findings. Statistical analysis was performed using SPSS version 20. Results: A total of 434 upper GI endoscopies were performed during the study period with thirty-one diagnosis of PUD made. The mean age of gastric ulcer (GU) and duodenal ulcer (DU) cases were 54.4 ± 20.2yrs and 48.1 ± 14.5yrs respectively (p = 0.367). GU to DU ratio was 1.4:1. H. pylori infection, chronic NSAID use and blood group O were seen in 7(22.5%), 8(25.8%) and 18(72.0%) respectively. Major indication in 21(67.7%) cases was gastrointestinal bleeding. Conclusion: There is a low diagnostic rate of PUD (6.7%) with pre-pyloric antral gastric ulcers as most common type and multifactorial aetiology. Keywords: Gastric ulcer; duodenal ulcer; endoscopy.

New ways in the treatment of gastric ulcer and duodenal ulcer

1936 ◽  
Vol 32 (8) ◽  
pp. 909-916
Author(s):  
Ya. I. Daikhovsky
Keyword(s):  
Duodenal Ulcer ◽  
Nervous System ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Gastric Ulcers ◽  
Duodenal Ulcers ◽  
Ulcer Disease ◽  
Local Disease

If until now the views of most authors still diverge on the pathogenesis of gastric ulcers, then there is complete unanimity in assessing the role of the nervous system in the development and course of gastric ulcers and duodenal ulcers, stomach ulcers and duodenal ulcers have long ceased to be considered as local disease, it is a manifestation of a disease of the whole organism with the localization of the process in the stomach or duodenal ulcer, which finds its expression in the term peptic ulcer disease. This view, firmly established in medicine, on stomach and duodenal ulcers is impossible, of course, not consider when it comes to treating this suffering.

Poor outcome and quality of life in female patients undergoing secondary surgery for recurrent peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A491-A491
Author(s):  
G GONZALEZSTAWINSKI ◽  
J ROVAK ◽  
H SEIGLER ◽  
J GRANT ◽  
T PAPPAS
Keyword(s):  
Quality Of Life ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Secondary Surgery ◽  
Ulcer Disease ◽  
Female Patients ◽  
Poor Outcome

Features of the course of peptic ulcer disease in children and adolescents

1985 ◽  
Vol 66 (5) ◽  
pp. 377-377
Author(s):  
N. A. Cherkasova ◽  
H. S. Bikbulatova ◽  
V. N. Leonova
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Children And Adolescents ◽  
Ulcer Disease

There were 26 patients with gastric ulcer and duodenal ulcer (17 boys, 9 girls) aged from 9 to 18 years under observation.

Features of Depressed State of Men with Sexual Disorders Based on Gastric Ulcer and Duodenal Ulcer

2016 ◽  
pp. 138-142
Author(s):  
Yurii Gurzhenko ◽  
Vasyl Soroka
Keyword(s):  
Duodenal Ulcer ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Peptic Ulcer Disease ◽  
Research Evaluation ◽  
Close Correlation ◽  
Sexual Disorders ◽  
Ulcer Disease ◽  
Negative Effect ◽  
Personal Anxiety

The aim of the research: evaluation of the peculiarities of anxiety in male patients with gastric ulcer and duodenal ulcer, which are sexual disorders. Materials and methods. The research is based on the generalization of the results of complex examination and treatment of 130 patients with peptic ulcer of duodenum and stomach in remission who have sexual disorders. The patients were divided into three groups: basic, comparative and referential. Was used C. Spielberger’s self-evaluation scale of situational and personal anxiety and M. Kurgan’s methodology. Results. It has been proven that the level of personal anxiety has a close correlation with the duration of peptic ulcer disease. Conclusion. The presence of peptic ulcer disease creates a certain basis for further psychological stress, similar to negative effect with the development of sexual disorders. Among the examined patients prevailed the somatized nature of depression.

Poor outcome and quality of life in female patients undergoing secondary surgery for recurrent peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A491
Author(s):  
Gonzalo V. Gonzalez-Stawinski ◽  
Jason M. Rovak ◽  
Hillard F. Seigler ◽  
John P. Grant ◽  
Theodore N. Pappas
Keyword(s):  
Quality Of Life ◽  
Peptic Ulcer ◽  
Peptic Ulcer Disease ◽  
Secondary Surgery ◽  
Ulcer Disease ◽  
Female Patients ◽  
Poor Outcome
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