scholarly journals Cytomorphological Profile of Thyroid Lesions on Fine Needle Aspiration Cytology

2021 ◽  
Vol 8 (7) ◽  
pp. 218-222
Author(s):  
Banasri Devi ◽  
Rachana Binayke ◽  
Brizellda Dcunha
Keyword(s):  
Thyroid Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions ◽  
Gland Enlargement

Background and Objectives: Fine needle aspiration cytology (FNAC) of thyroid offers an alternative, as an immediate, preliminary procedure associated with low cost, little trauma and complications. Being superficial and easily accessible it is an ideal organ for FNAC. It is useful in diagnosis of inflammatory, infectious and neoplastic conditions. The aim of this study was to evaluate the cytomorphological profile of thyroid lesions on FNAC with application of Bethesda system for reporting and perform cyto-histopathology correlation whenever possible with regards to age and sex distribution. Methodology: This two-year prospective study was conducted in the Cytology section of Pathology Department & included 243 cases of thyroid gland enlargement. The detailed history of the patient including age, sex, presenting symptoms and duration of thyroid gland enlargement along with any other significant findings was note. FNAC was performed as per the protocol using a 23-gauge needle and smears stained using Haematoxylin & Eosin (H&E) and Papanicolaou stain, while air-dried smears were stained with Giemsa stain. Results: The study period included a total of 243 FNACs of thyroid enlargement. The age of patients ranged from 10 to 80 years with male to female ratio of 1.4. The diagnosis on FNAC was as follows Colloid Goitre (54.7 %), Lymphocytic Thyroiditis (9.54%), Follicular Neoplasm (7.05%), Hashimoto Thyroiditis (5.80 %), Benign Thyroid Lesions (3.31%) and Multinodular Goitre (2.90%). Conclusion: Thyroid fine needle aspiration cytology has proven to be a first line tool to evaluate the thyroid lesions because of its cost effectiveness and high patient acceptance. Fine needle aspiration cytology is highly successful in triaging patients with thyroid nodules into operative and non-operative groups and enables surgeons to take an early decision regarding mode of treatment. The Bethesda system for reporting of thyroid lesions aims at standardization of reports. It makes the cytology report unambiguous and clinically relevant. Keywords: Fine needle aspiration cytology, thyroid lesions.

Cytopathological Evaluation of Thyroid Lesions Based on Bethesda System in Patients Attending Birat Medical College and Teaching Hospital

2020 ◽  
Vol 22 (4) ◽  
pp. 260-265
Author(s):  
Neeta Kafle ◽  
B Koirala ◽  
SU Kafle ◽  
M Singh ◽  
A Sinha
Keyword(s):  
Teaching Hospital ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Medical College ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

More than 50% of the world’s population has at least a thyroid nodule. Detail clinical examination and radiology may help in diagnosing thyroid lesions but the management depends upon the cytopathological diagnosis. Optimum use of fine needle aspiration cytology (FNAC) and better understanding of cytomorphological characteristic of thyroid lesions by using Bethesda system, triaging of patients who are to be treated medically or surgically is more accurate. The objective of this present study is cytopathological evaluation of thyroid lesions based on Bethesda System in patients attending Birat Medical College and Teaching Hospital. The objective was also to correlate the cytological findings with histopathological findings where ever possible. A total of 104 patients with thyroid lesions underwent fine needle aspiration cytology in a period of a year (September 1, 2019 to August 31, 2020). Cytological features were evaluated and classified according to the Bethesda system. Histopathological features were evaluated and correlated wherever available. Among 104 patients with thyroid lesions 93 were female and 11 were male. Four cases turned out to be non diagnostic, 85 benign, three Atypia of undetermined significance, three Suspicious for follicular neoplasm and eight Suspicious of malignancy and one Malignant according to Bethesda system. Histopathology specimen was received in 31 patients out of whom 20 (64.5%) patients were reported as colloid nodule, two follicular adenoma, one Hurthle cell adenoma, six papillary carcinoma and two follicular carcinoma. Medullary carcinoma and anaplastic carcinoma were not seen in the patients evaluated. Specificity and sensitivity of fine needle aspiration cytology was 94.7% and 88.9% respectively. Thus reporting thyroid lesions FNAC with Bethesda system allow a more specific cytological diagnosis.

scholarly journals The spectrum of thyroid lesions on fine needle aspiration cytology

2020 ◽  
Vol 8 (2) ◽  
pp. 630
Author(s):  
Yashika P. Jaiswal ◽  
Sanjay Chawhan
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Follicular Neoplasm ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
The Bethesda System ◽  
Thyroid Lesions

Background: Fine Needle Aspiration Cytology (FNAC) of thyroid gland is the most common preoperative investigation for diagnosis of thyroid lesions. Though various tests like thyroid profile, ultrasonography and radionuclide scan are available, they are used as adjuvant diagnostic modalities. FNAC is simple, easy to perform, non-invasive and cost-effective procedure. Primary aim is to study the spectrum of various thyroid lesions on FNAC. Also, the study is aimed to categorise the thyroid lesions according to the Bethesda system for Reporting Thyroid Cytopathology (2017).Methods: This is a retrospective observational study carried out in the pathology department at tertiary care academic institute for a period of three years. FNAC was done in a patient with thyroid swelling by non-aspiration technique. Slides were prepared, fixed in 95% ethyl alcohol and processed with routine stains.Results: Out of 210 cases, 150 cases (71.42%) were benign lesions, 15 cases (7.14%) were Follicular neoplasm/Suspicious for follicular neoplasm, 14(6.66%) cases were reported as Atypia of undetermined significance, 13 cases (6.19%) were Unsatisfactory/Nondiagnostic, 11 cases (5.2%) were malignant and 7 cases (3.3%) were suspicious for malignancy.Conclusions: FNAC is the most effective tool for the diagnosis of thyroid lesions. The Bethesda system is used to categorise the thyroid lesions and helps in better communication between clinicians and pathologists for the best surgical and medical management. The number of benign cases were higher and the number of cases in the category of suspicious for malignancy were lower with female preponderance.

scholarly journals A study on fine needle aspiration cytology of thyroid lesions with correlation to histopathological examination with special reference to Bethesda system of reporting at a tertiary care centre

2019 ◽  
Vol 8 (1) ◽  
pp. 260
Author(s):  
Nandinee Lahkar ◽  
Manoj Kumar Deka ◽  
Nitu Mani Khakhlari
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cost Effective ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Bethesda System ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity ◽  
Thyroid Lesions

Background: Annual incidence of thyroid nodules ranges from 40,000 to 70,000 per 1 lac population worldwide. Fine Needle Aspiration (FNA) of the thyroid is widely accepted simple, cost effective and quick to perform outpatient procedure with minimal complication. The National Cancer Institute (NCI) Bethesda, Maryland, United States standardized the reporting system for thyroid FNA by using Bethesda system for reporting thyroid cytopathology.Methods: FNA was performed in total 155 patients presenting with the thyroid swelling with or without Ultrasonography (USG) guidance. All patients were analyzed for age, gender, type of lesions. FNA was done and smears were examined and reported according to Bethesda system of reporting for thyroid cytopathology. Findings were correlated with post-operative histopathological diagnoses in 103 cases who underwent surgery.Results: Out of total 155 patients, 32 were male and 123 were female. Average age of presentation was 38.4 years. On cytology, according to Bethesda system, most cases were in benign category (76.1%) followed by malignant (8.4%). On histopathological study most common diagnosis was colloid goiter followed by papillary thyroid carcinoma. From the study it was found that sensitivity, specificity and accuracy of fine needle aspiration cytology of thyroid lesions were 81.8%, 97.3% and 95.4% respectively.Conclusions: Fine needle aspiration cytology is simple, easy to perform, cost effective procedure with high sensitivity, specificity and diagnostic accuracy in case of thyroid lesions.

Sign in / Sign up

Export Citation Format

Share Document