scholarly journals HISTOPATHOLOGICAL DIAGNOSTICS OF TESTICULAR SERTOLI CELL TUMOR IN INGUINAL CRYPTORCHIDISM

2021 ◽  
pp. 59-66
Author(s):  
E.M. Zotova ◽  
◽  
E.M. Maryin ◽  
M.A. Bogdanova ◽  
V.A. Ermolaev ◽  
...  
Keyword(s):  
Sertoli Cell ◽  
Spermatic Cord ◽  
Secretory Activity ◽  
Excisional Biopsy ◽  
Cell Tumor ◽  
Sertoli Cell Tumor ◽  
Regional Lymph Nodes ◽  
Metastatic Activity ◽  
The Right ◽  
Degree Of Differentiation

The research was carried out in the Interdepartmental Scientific Veterinary Center of Veterinary Medicine based in the Ulyanovsk State Agricultural University. We studied the testis tumor - sertoli cell tumor, according to histological classification, in a male dog with inguinal cryptorchidism. The research goal was to study possible changes in the differentiation, hormonal and metastatic activity of sertoli cell tumor in case of inguinal cryptorchidism in comparison with this type of tumor in physiologically located testes, described in literature. The clinical examination revealed the presence of left-sided inguinal cryptorchidism as well as signs of hyperestrogenism: hyperpigmentation and non-inflammatory alopecia of scrotum, prepuce, located sym-metrically in the right and left iliac regions of the abdomen. The studied neoplasm showed the presence of a dense capsule, the absence of infiltrative growth and metastases in the regional lymph nodes, distinct secretory activity. Fragments of tumor tissue from the testis, epididymis and spermatic cord were obtained for histological examination by the means of excisional biopsy. As a result, the neo-plasm was found to be a sertoli cell tumor of a high degree of differentiation. The tissues of the epididymis showed a significant thickening of the stroma due to the proliferation of connective tissue - a sign of severe sclerosis. The mi-croslides of the spermatic cord and epididymis did not show any signs of infiltrative growth or metastatic spread of tumor cells which meant that the relative benign quality of sertoli cell tumor was found in this clinical study of inguinal cryptorchidism.

scholarly journals Large Cell Calcifying Sertoli Cell Tumor with Macrocalcification in a Partially Resected Testis

2020 ◽  
Vol 2020 ◽  
pp. 1-4 ◽  
Author(s):  
Mahmoud Bardisi ◽  
Mohamad Nidal Khabaz ◽  
Jaudah Ahmad Al-Maghrabi
Keyword(s):  
Sertoli Cell ◽  
Large Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor ◽  
Left Testis ◽  
Palpable Mass ◽  
Grade 3 ◽  
The Right ◽  
Radiological Studies ◽  
Sertoli Cell Tumors

Large cell calcifying Sertoli cell tumors (LCCSCTs) are extremely rare, with less than 100 tumors being described to date. Most of the tumors are benign with a few malignant cases, and aggressive behavior is infrequent. These tumors are a type of Sertoli cell tumor, and these tumors comprise less than 0.3% of all testis tumors in Saudi Arabia. They usually occur in boys and young adults and can affect one or both testicles in multifocal form causing microcalcifications. A 28-year-old male visited our hospital with left testis pain. Physical examination of the scrotum revealed that both testicles were normal sized with no palpable mass. Ultrasonography evaluation revealed grade 3 left varicocele and an incidental 9 mm calcified mass in the right testicle, which was further confirmed by MRI. Partial orchiectomy was performed. Clinical data, radiological studies, and morphological and immunohistochemical characteristics were analyzed.

Sertoli cell tumor of the testis causing intracranial metastasis two years after orchiectomy. Report of a rare case and review of the literature

2021 ◽  
Author(s):  
Antonio Colamaria ◽  
Matteo Sacco ◽  
Giovanni Parbonetti ◽  
Nicola Pio Fochi ◽  
Francesco Carbone ◽  
...  
Keyword(s):  
Sertoli Cell ◽  
Present Report ◽  
Cell Tumor ◽  
Sertoli Cell Tumor ◽  
Testicular Tumors ◽  
Intracranial Metastasis ◽  
Leptomeningeal Involvement ◽  
Multiple Metastases ◽  
History Of ◽  
The Right

Abstract Sertoli cell tumor of the testis (SCTT) accounts for less than 1% of all testicular tumors with only 10% of cases exhibiting malignant behavior. In the present report, a case of malignant SCTT causing multiple metastases in a 32-year-old man is described. After being diagnosed and treated for bone and lymph nodes metastases, the patient presented with a brief history of worsening headaches and visual impairment. A head MRI demonstrated an extra-axial tumor located in the right fronto-parietal junction exhibiting avid contrast enhancement and leptomeningeal involvement. To the best of the authors’ knowledge, this represents the second case of intracranial metastasis from SCTT described to date.

scholarly journals Testicular Neoplasia in the Retained Testicles of an Intersex Male Dog

2012 ◽  
Vol 48 (2) ◽  
pp. 118-124 ◽  
Author(s):  
Aaron M. Herndon ◽  
Margret L. Casal ◽  
John T. (Scott) Jaques
Keyword(s):  
Sertoli Cell ◽  
Leydig Cells ◽  
Testicular Tissue ◽  
Cell Tumor ◽  
Sertoli Cell Tumor ◽  
Before And After ◽  
Male Sex ◽  
The Right ◽  
Phenotypic Female ◽  
Irregular Mass

This case describes the presentation and management of an 8 yr old phenotypically female intersex male dog presented for evaluation of a mass in the right inguinal region. The right inguinal space was surgically explored, and a large irregular mass resembling a fully developed testicle was identified in the right vaginal tunic. A second mass resembling an atrophied, but anatomically mature testicle, was identified in the left tunic. The larger mass was identified as a Sertoli cell tumor that had replaced all normal testicular tissue. The smaller mass was identified as a testicle that contained a small intratubular seminoma. The patient was diagnosed as having a phenotypic female sex, chromosomal male sex, and a gonadal male sex. Hormone assays completed before and after the gonadectomy and mass removal document an elevation of circulating progesterone presurgically that returned to baseline by 1 mo postsurgically. The source of the progesterone was identified to be the Leydig cells of the atrophied testicle.

Inoperable Ovarian Sertoli Cell Tumor in an Elderly Patient, Case Report and Review of Literature

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Bedoudou H ◽  
Aboueljaoud B ◽  
Mai A ◽  
Banani A ◽  
Alaoui Lamrani Y ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Sertoli Cell ◽  
Cell Tumor ◽  
Review Of Literature ◽  
Sertoli Cell Tumor ◽  
Patient Case

Testicular Tumors—Some New and a Few Perennial Problems

2008 ◽  
Vol 132 (4) ◽  
pp. 548-564 ◽  
Author(s):  
Robert H. Young
Keyword(s):  
Germ Cell ◽  
Sertoli Cell ◽  
Leydig Cell ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Female Gonad ◽  
Sertoli Cell Tumor ◽  
Older Patient ◽  
Testicular Tumors

Abstract The histopathology of testicular tumors is presented, emphasizing new, unusual, or underemphasized aspects. Within the category of seminoma of the usual type, the recent literature has drawn attention to the presence in occasional tumors of solid or hollow tubules or spaces of varying sizes and shape that may result in cribriform or microcystic patterns, causing potential confusion with other neoplasms, most notably Sertoli cell tumor or yolk sac tumor. Although regions of typical neoplasia and awareness of this phenomenon usually will be diagnostic, immunohistochemistry may play a role in excluding Sertoli cell tumor or yolk sac tumor. Although immunohistochemistry can play an undoubted helpful role in this and selected other areas of testicular tumor evaluation, careful evaluation of the gross and routine microscopic features will solve the vast majority of diagnostic problems. An excellent review of immunohistochemistry in this area by R. E. Emerson, MD, and T. M. Ulbright, MD, is cited herein. Spermatocytic seminoma remains a crucial pitfall in diagnosis, and the pathologist must always be alert to the possible diagnosis when looking at a seminomatous neoplasm, particularly in an older patient, although about one third of these tumors occur in the usual seminoma age range. The embryonal carcinoma has a great diversity of patterns, which are briefly noted. The enigmatic and picturesque tumor, polyembryoma, which virtually never occurs in pure form but may be a confusing component of a variety of mixed germ cell tumors, is discussed and illustrated. The phenomenon of burnt-out germ cell neoplasia is also briefly noted and an excellent recent contribution is referred to. Within the sex cord–stromal family of neoplasms, recent contributions and elaborations of unusual morphologic features of Leydig cell tumors and Sertoli cell tumors are presented. Within the Leydig cell family, cyst formation, adipose metaplasia, calcification or ossification, and spindle cell patterns may be particularly confusing, and in the Sertoli cell family, a great array of patterns caused by differing admixtures of tubular, solid, and stromal components occur. The peculiar lesion, intratubular large cell hyalinizing Sertoli cell tumor, of young boys with Peutz-Jeghers syndrome, is briefly discussed. Some of the problems in the family of hematopoietic neoplasms are reviewed, these processes posing diverse problems in differential diagnosis and their correct recognition having crucial therapeutic implications. Although secondary tumors to the testis have not received the same attention in the literature as the similar phenomenon in the female gonad, remarkable examples of testicular spread of diverse neoplasms, usually carcinoma but rarely melanoma, are seen, and the pathologist should be alert to this possibility, particularly when examining an unusual morphology in an older patient. Finally, a few comments are made on the common paratesticular neoplasm, the adenomatoid tumor, highlighting its varied patterns and recent description of some of the issues that may arise when they undergo total or subtotal infarction.

Sertoli Cell Tumor

2022 ◽  
pp. 1349-1354
Author(s):  
Cynthia M. Faux ◽  
Marcie L. Logsdon
Keyword(s):  
Sertoli Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor

NSE positive Sertoli cell tumor of the testis: case report and literature review

2020 ◽  
Vol 216 (8) ◽  
pp. 152990
Author(s):  
Gregor Mikuz ◽  
Elisabeth Wadl ◽  
Pavlos Raptis ◽  
Klaus Jeschke ◽  
Hermann Rogatsch
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Sertoli Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor
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