Osteosarcoma of the Clavicle and Scapula Secondary To the Radiotheraphy for Servical Metastases of the Differentiated Thyroid Cancer: Case Report

2010 ◽  
Vol 30 (1) ◽  
pp. 413-415
Author(s):  
Savaş KARYAĞAR ◽  
Mehmet MULAZIMOGLU ◽  
Sevda SAĞLAMPINAR KARYAĞAR ◽  
Ercan UYANIK ◽  
Tevfik ÖZPAÇACI
1993 ◽  
Vol 47 (6-7) ◽  
pp. 253
Author(s):  
R. Russo ◽  
M. Cappagli ◽  
P. Poggi ◽  
R. Leoconcini ◽  
C. De Gaudio ◽  
...  

2014 ◽  
Vol 28 (5) ◽  
pp. 472-476 ◽  
Author(s):  
Alfredo Campennì ◽  
Rosaria M. Ruggeri ◽  
Salvatore Giovinazzo ◽  
Alessandro Sindoni ◽  
Domenico Santoro ◽  
...  

HORMONES ◽  
2015 ◽  
Author(s):  
Alfredo Campennì ◽  
Salvatore Giovinazzo ◽  
Lorenzo Curtò ◽  
Ernesto Giordano ◽  
Maria Trovato ◽  
...  

Author(s):  
Ivana Puliafito ◽  
Caterina Puglisi ◽  
Stefania Marchisotta ◽  
Pasquale Malandrino ◽  
Paolo Giuffrida ◽  
...  

2021 ◽  
Vol 11 ◽  
Author(s):  
Rachael Wybrew ◽  
Michael Loynd ◽  
Maria Wybrew ◽  
Leslie Samuel

This case report describes an elderly patient with radioiodine-resistant differentiated thyroid cancer and additional multiple metastases living in a rural setting, remote from the specialist oncology service. This case is of interest because effective systemic therapies for treatment-resistant cancers, such as lenvatinib, are now available but can potentially cause significant toxicities that require extensive medical management. Here, we discuss how patient care was provided collaboratively by the local community teams integrated with remote specialist oncology services. A 77-year-old patient presented with symptoms of cauda equina secondary to a large metastatic sacral deposit. The deposit was biopsied, and histology revealed a diagnosis of differentiated follicular thyroid cancer that was treated with external beam radiotherapy and thyroidectomy, followed by radioiodine. However, the disease was found to be resistant to radioiodine therapy, and the patient subsequently developed back pain due to new bone metastases. After further palliative external beam radiotherapy, the patient was started on systemic treatment with lenvatinib. Treatment has continued for more than 2.5 years with a slow but steady improvement in symptoms and quality of life. Monitoring and assessment of lenvatinib therapy and management of associated toxicities was coordinated remotely from a specialist cancer center over 200 miles away, using the skills of the local medical and nursing teams. This case report demonstrates how a cooperative effort using local teams and video-conferencing links to a specialist cancer center can be applied to safely treat a patient with a medication that may result in significant potential toxicities that require attentive and dynamic management.


1989 ◽  
Vol 120 (5) ◽  
pp. 547-558 ◽  
Author(s):  
Line Baldet ◽  
Jean-Claude Manderscheid ◽  
Daniel Glinoer ◽  
Claude Jaffiol ◽  
Béatrice Coste-Seignovert ◽  
...  

Abstract. In order to know how thyroid nodules and differentiated thyroid cancers are investigated and treated in 1988, an international inquiry was performed by mean of a questionnaire based on a well-defined case report of a 35-year-old female with a solitary small thyroid nodule. Clinicians were asked to indicate their diagnostic and therapeutic approaches to the reported case and to some variations. Analysis of the 157 responses from thyroid experts showed that three in vitro tests (sensitive-TSH, free T4 and total T4) and three in vivo tests (99mTc or radioiodide scintiscan, fine needle aspiration and ultrasonography) were performed most frequently. In the case of a solid and cold nodule and in the absence of fine needle aspiration results, 19% of respondents advocated suppressive therapy and 81% surgery. In the same clinical case, but whom fine needle aspiration had been performed and cytology was benign, surgery was advocated by 24%, suppressive therapy by 48% and a regular follow-up without treatment by 28% of respondents. When surgery was performed and the diagnosis was a differentiated thyroid cancer, (near) total thyroidectomy was more frequently chosen than partial thyroidectomy in both papillary (60 and 40%, respectively, of respondents) and follicular (74 and 26%, respectively, of respondents) cancers; 80% of clinicians did not change their surgical technique in relation to histological type of the tumour. Total thyroidectomy was more often recommended in most of the clinical or anatomical variations compared with the basic case report. Pre- or postoperative hormonal therapy was initiated with L-T4 and TSH suppression was controlled by sensitive-TSH and thyroglobulin determinations. After total thyroidectomy, 131I was used with similar modalities for papillary and follicular cancers to ablate a thyroid remnant.


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