scholarly journals Isolation and Characterization of Complement System Activating Polysaccharides from the Hot Water Extract of the Leaves of Capsicum annuum L.

2002 ◽  
Vol 12 (1) ◽  
pp. 87-95
2009 ◽  
Vol 344 (17) ◽  
pp. 2412-2416 ◽  
Author(s):  
Ramsankar Sarkar ◽  
Chanchal K. Nandan ◽  
Soumitra Mandal ◽  
Pradip Patra ◽  
Debsankar Das ◽  
...  

2003 ◽  
Vol 81 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Wen Zhu ◽  
Vincent E.C Ooi ◽  
Paul K.S Chan ◽  
Put O Ang Jr.

Bioactivity-guided fractionation of the hot water extract from the brown alga Sargassum patens led to the isolation of a polysaccharide as an antiviral component against herpes simplex viruses which are the cause of cold sores (HSV-1) and genital herpes (HSV-2). The polysaccharide contained a sulfur group that could be present as a sulfate ester. It is thus a sulfated polysaccharide with a molecular mass of about 424 kDa, and is designated SP-2a. Gas chromatographic assay showed that the polysaccharide consisted of fucose, galactose, mannose, xylose, glucose, and galactosamine. The fucose is the major constituent sugar (35.3%), followed by galactose (18.4%). The 50% effective concentration (EC50) against HSV-2, HSV-1, and HSV-1 acyclovir resistant strain was 1.3, 5.5, and 4.1 µg/mL, respectively. The 50% cytotoxic concentration (CC50) of SP-2a on the growth of normal Vero cell line was more than 4000 µg/mL. Therefore SP-2a of S. patens may be a potent agent for treating HSV infections. Key words: sulfated polysaccharide, anti-herpes activities, brown alga, Sargassum.


2017 ◽  
Vol 64 (4) ◽  
pp. 83-90
Author(s):  
Ikuko Kakizaki ◽  
Ayako Miura ◽  
Takashi Mineta ◽  
Jinseo Hong ◽  
Yoji Kato

2012 ◽  
Vol 35 (4) ◽  
pp. 810-817 ◽  
Author(s):  
Xuefeng Hao ◽  
Changming Chen ◽  
Guoju Chen ◽  
Bihao Cao ◽  
Qinghua Chen ◽  
...  

2021 ◽  
Vol 45 ◽  
Author(s):  
Sarah Rebeka Rodrigues Marques ◽  
Tatiane Kelly Barbosa Azevêdo ◽  
Aline Rogéria Freire de Castilho ◽  
Renata Martins Braga ◽  
Alexandre Santos Pimenta

ABSTRACT Condensed tannins are chemical compounds derived from the secondary metabolism of plants. They are of particular interest due to their broad range of technological uses and applications. The objective of this study was to extract, quantify, and characterize by Fourier-transform infrared spectroscopy (FTIR) the bark tannins of four forest species grown in Northeast Brazil: Acacia mangium, Azadirachta indica, Mimosa tenuiflora, and Mimosa caesalpiniifolia. Bark samples were collected from 5 trees of each species grown in a five-year-old forest stand. Samples were collected, grounded, and submitted to extraction with hot water, then measured to determine total solids content (TSC), Stiasny number (SN), and condensed tannins content (CTC). FTIR spectra were acquired from tannin samples fixed in potassium bromide pellets. Among the four species, M. tenuiflora presented the highest CTC, equal to 23.4%, and the purest crude hot-water extract with SN of 91.27%. Based on FTIR characterization, tannins from M. caesalpiniifolia, A. indica, and A. mangium barks were classified as proanthocyanidins and those from M. tenuiflora bark as prodelphinidins.


2010 ◽  
Vol 81 (3) ◽  
pp. 584-591 ◽  
Author(s):  
Sukesh Patra ◽  
Kankan K. Maity ◽  
Sanjoy K. Bhunia ◽  
Biswajit Dey ◽  
Debsankar Das ◽  
...  

2014 ◽  
Vol 20 (2) ◽  
pp. 505-507 ◽  
Author(s):  
Yukinori Yabuta ◽  
Eri Hashimoto ◽  
Takashi Takeuchi ◽  
Setsuko Sakaki ◽  
Yuji Yamaguchi ◽  
...  

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