scholarly journals Living-related liver transplant to treat epithelioid hemangioendothelioma – a case report

2005 ◽  
Vol 8 (4) ◽  
pp. 449-451
Author(s):  
Marcelo A. F. Ribeiro Jr ◽  
Christian Evangelista Garcia ◽  
Telma Eugênio dos Santos ◽  
Adavio de Oliveira e Silva ◽  
Regina Leitão ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Liver Transplant ◽  
Soft Tissues ◽  
Liver Tumors ◽  
Epithelioid Hemangioendothelioma ◽  
Low Grade ◽  
Living Related Liver Transplant ◽  
Transplantation Technique ◽  
Living Related

Introduction: Epithelioid hemangioendothelioma of liver is a rare, low-grade neoplasm of vascular origin that has an unpredictable malignant potential. It preferentially arises in soft tissues and bones, and seldom in the liver. Biologically, it trends to be multi-focal and often unresectable. Objective: The outcome of a patient submitted to a living-related liver transplant to treat epithelioid hemangioendothelioma of the liver. Case report: The reported case involves a 39-year old female patient with an immense epithelioid hemangioendothelioma of the liver, involving segments III, IV, V, VII, and VIIl. The prognostic to any kind of treatment was considered unfavorable, and the decision of submitting her to a liver transplant was made. It was suggested a living-related liver transplant. The donor was the patient’s 36-year old brother, who donated his right liver lobe (segments V, VI, VII, VIII). The recipient´s original liver was large, presenting very solid consistence and no node evidence. The transplant itself was performed using the conventional living-related liver transplantation technique. The recovery was good, and she was discharged from hospital on the 15th postoperative day using micophenolate mofetil, tacrolimus, and corticoid. Conclusion: Liver transplantation for epithelioid hemangioendothelioma of the liver can be performed with acceptable survival rate. The living related liver transplant opens a great perspective to that group of patients presenting liver tumors and who are unfeasible to wait for an organ on a waiting list.

LIVING RELATED LIVER TRANSPLANTATION FOR EPITHELIOID HEMANGIOENDOTHELIOMA – A CASE REPORT

2004 ◽  
Vol 78 ◽  
pp. 722
Author(s):  
M A.F. Ribeiro ◽  
C E. Garcia ◽  
T E. dos Santos ◽  
J M. P. Manceiro ◽  
J L.M. Copstein ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Epithelioid Hemangioendothelioma ◽  
Living Related Liver Transplantation ◽  
Living Related

scholarly journals Metastatic Hepatic Epitheloid Hemangioendothelioma in a Young Male: A Rare Presentation

2021 ◽  
Vol 8 (2) ◽  
pp. 58-62
Author(s):  
Tanweerul Huda ◽  
Mohammad Masoom Parwez ◽  
Bharati Pandya
Keyword(s):  
Liver Transplantation ◽  
Incisional Hernia ◽  
Soft Tissues ◽  
Young Male ◽  
Chemotherapeutic Agents ◽  
Epithelioid Hemangioendothelioma ◽  
Low Grade ◽  
Rare Presentation ◽  
Large Defect ◽  
Multiple Biopsies

Hepatic EHE (epithelioid hemangioendothelioma) is an uncommon entity of vascular origin and a low-grade malignant tumor. Primary hepatic EHE is rare. These tumors can be multifocal at presentation like in the soft tissues, bones, brain, liver, and small intestine. First described by Weiss and Enzinger in 1982 as a malignant vascular neoplasm with indolent behavior. We report the case of a 23-year-old male, known case of chronic liver disease, who presented with incisional hernia following exploratory laparotomy 8 months back, performed for intestinal obstruction. Contrast-enhanced computed tomography abdomen revealed an incisional hernia with a large defect along with multiple lesions in the liver (suspected metastases) and peritoneal deposits and a few discrete lung nodules. Some areas of interloop collections were also noted. Biopsies were taken from the liver which revealed benign cirrhotic lesion. Relevant to the findings, multiple biopsies were performed and fluid was sent for evaluation. The liver biopsy came out positive for borderline vascular malignancy (epithelioid hemangioendothelioma). This was confirmed with the immunohistochemistry report. Epithelioid hemangioendothelioma occurs mostly in soft tissues of extremity and lungs. The involvement of the liver may be seen as metastasis or rarely as a primary tumor. The incidence of primary malignant hepatic hemangioendothelioma is about 0.1/100,000; the mean age at the time of diagnosis is 41.7 years, and male:female ratio is 2:3. Liver transplantation, hepatectomy, chemoembolization, radiotherapy, and chemotherapeutic agents are reported treatment regimens. Malignant EHE of liver presents as multiple hepatic nodules. Being locally aggressive, it can invade the peritoneum, gut, and lungs. Orthoptic liver transplantation appears to be the only remedy because of the multifocal nature of the disease. Partial hepatectomy is possible for localized tumors.

scholarly journals Hypoglycemic syndrome in hepatic epithelioid hemangioendothelioma, successful treatment — liver transplantation from a living related donor

2019 ◽  
Vol 65 (1) ◽  
pp. 50-56
Author(s):  
Irina A. Bondar ◽  
Ludmila I. Chesnochenko ◽  
Olesia Yu. Shabelnikova ◽  
Ivan A. Porshennikov
Keyword(s):  
Liver Transplantation ◽  
Liver Tumors ◽  
Malignant Neoplasm ◽  
Epithelioid Hemangioendothelioma ◽  
Malignant Neoplasms ◽  
Mesenchymal Tumors ◽  
Large Tumor ◽  
Life Saving ◽  
Living Related ◽  
Somatic Diseases

Hypoglycemic syndrome occurs not only in endocrine diseases but can complicate the course of many somatic diseases and tumors of pancreatic and extra-pancreatic localization. Development of hypoglycemia in liver tumors is associated with a decrease in the volume of functioning liver tissue, increased consumption, and utilization of glucose by the tumor tissue, inhibition of gluconeogenesis and glycogenolysis, and secretion of insulin-like peptides. Hypoglycemia in liver tumors is rarely the first symptom of the disease and usually occurs in patients with large tumor sizes and symptoms of tumor intoxication. Epithelioid hemangiendothelioma of the liver is the primary malignant neoplasm from the group of mesenchymal tumors, it occurs less than in 1% of cases of all malignant neoplasms of the liver. The clinical course of epithelioid hemangiendothelioma of the liver is highly variable. There are slowly and rapidly progressing variants. The diagnosis is based on the results of histological and immunohistochemical examination of the postoperative material. In the literature there is no description of hypoglycemia in epithelioid hemangiendothelioma. We report a patient with severe hypoglycemic syndrome, which was due to an epithelioid hemangioendothelioma of the liver. Pharmacological treatment of hypoglycemia was ineffective. The presence of massive bilobar tumor made it impossible to use a liver resection. Hepatectomy with living related liver transplantation was life-saving procedure and made it possible to eliminate hypoglycemia.

scholarly journals Extraskeletal Chondroma of the Index Finger: A Case Report

2017 ◽  
Vol 10 (2) ◽  
pp. 479-484 ◽  
Author(s):  
Masato Saito ◽  
Kazumasa Nishimoto ◽  
Robert Nakayama ◽  
Kazutaka Kikuta ◽  
Masaya Nakamura ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissues ◽  
Hyaline Cartilage ◽  
Index Finger ◽  
Tendon Sheath ◽  
Low Grade ◽  
Treatment Experience ◽  
Cartilaginous Tumor ◽  
Bone Cortex ◽  
Histopathologic Findings

Extraskeletal chondroma is defined as a rare, benign, cartilaginous tumor arising from soft tissues such as tendons, tendon sheath synovia, and joint capsules with no continuity to the periosteum or bone cortex. In histopathologic findings, the tumor exhibits many lobular structures and some parts similar to hyaline cartilage. Therefore, it is sometimes difficult to differentiate this tumor from low-grade chondrosarcoma because of their similar histopathologic findings. In order to prevent recurrence, it is necessary to remove the tumor as a whole, including the capsule, so as not to leave any remnants of the tumor. In this article, we report our treatment experience with a case of extraskeletal chondroma in the index finger of a 63-year-old patient.

Adult to adult living-related liver transplant: Report on an initial experience in Italy

2007 ◽  
Vol 39 (4) ◽  
pp. 342-350 ◽  
Author(s):  
S. Gruttadauria ◽  
J.W. Marsh ◽  
D. Cintorino ◽  
D. Biondo ◽  
A. Luca ◽  
...  
Keyword(s):  
Liver Transplant ◽  
Initial Experience ◽  
Living Related Liver Transplant ◽  
Living Related
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