cartilaginous tumor
Recently Published Documents


TOTAL DOCUMENTS

44
(FIVE YEARS 9)

H-INDEX

9
(FIVE YEARS 1)

2022 ◽  
Vol 6 ◽  
pp. 2
Author(s):  
Benson Li ◽  
Serenella Serinelli ◽  
Gustavo de la Rosa ◽  
Timothy Arthur Damron

Needle biopsy of an incidental periacetabular bone lesion in an 18-year-old female showed a low-grade cartilaginous tumor. Based on the imaging and pelvic location, the tumor was considered a Grade I chondrosarcoma. Due to the young age, incidental discovery, and low metastatic potential, radiofrequency ablation (RFA) was recommended in favor over traditional wide en bloc resection. The patient has been radiographically and clinically stable for 2 years. RFA has not been previously reported for low-grade chondrosarcoma. Its use should be done only with careful consideration and diligent follow-up in this setting.


2021 ◽  
Vol 11 ◽  
Author(s):  
Yamato Suemitsu ◽  
Yusuke Ono ◽  
Yusuke Mizukami ◽  
Juanjuan Ye ◽  
Keiko Yamakawa ◽  
...  

BackgroundPancreatoblastoma is a rare malignant epithelial neoplasm of the pancreas that mainly occurs in children and involves abnormalities in the WNT/β-catenin pathway, such as CTNNB1 mutation. However, the molecular abnormalities in adult pancreatoblastoma are not well known.Case PresentationAn elderly man, who underwent elective distal pancreatectomy and splenectomy, was referred to our hospital with a mass in the tail of the pancreas. Histologically, the lesion revealed proliferation of clear, basophilic, and cartilaginous tumor cells with lymphatic metastasis. Each of the morphologically distinct tumor components showed different immunohistochemical patterns, indicating heterogeneous differentiation, including epithelial (both acinar and ductal), mesenchymal, and neuroendocrine differentiation. All tumor components showed nuclear expression of β-catenin and cyclin D1. Per next-generation sequencing (NGS), the clear and basophilic tumor cells shared mutations in APC, GRM8, LAMP1, and AKA9. Among the mutations, APC, c.1816_1817insA showed the highest frequency in both cell types, indicating that APC mutation was a driver mutation of the tumor. A diagnosis of PB was rendered.SummaryIn conclusion, the clear and basophilic cells of the tumor were supposedly derived from the same clone and subsequently acquired additional mutations. This is the first report of clonal evolution in pancreatoblastoma.


2021 ◽  
Vol 11 (7) ◽  
Author(s):  
Keerthan Ranga Nayak ◽  
Sharath Kumar Rao ◽  
Sharath Kumar Rao ◽  
Sharath Kumar Rao

Introduction: Enchondroma is a solitary, benign, intramedullary cartilaginous tumor commonly noticed in the phalanges of hands and feet with characteristic radiological features. Its occurrence in aberrant sites with atypical features lead to diagnostic dilemma. Enchondromas which are usually managed non-operatively can mimic other benign and malignant lesions, especially chondrosarcoma. Case Report: We report the case of a 31-year-old farmer who presented with long standing inconspicuous pain in his left leg which turned out to be a diaphyseal enchondroma even though it demonstrated aggressive radiological features mimicking a chondrosarcoma. Incisional biopsy was done from the scalloped areas to obtain the correct histological diagnosis. He underwent thorough curettage of the lesion and remains asymptomatic 2 years after the procedure. We attempt to discuss the differentials which the orthopedic surgeon should keep in mind for diaphyseal lesions mimicking enchondroma. Conclusion: Though classically found in metaphysis, Enchondromas are not uncommon in diaphysis of long bones. Enchondromas are generally benign, but can cause diagnostic dilemma when they present with aggressive features at rare locations and surgeons should be wary of the differentials. Despite a size of more than 6 cm and evidence of cortical erosion and intramedullary widening, the lesion could still be benign. Early biopsy will help to differentiate Enchondroma from a malignant transformation or malignant tumor. Keywords: Enchondroma, chondrosarcoma, diaphysis, multilocular, endosteal scalloping, chondroma.


2021 ◽  
Vol 5 (2) ◽  
pp. 10-14
Author(s):  
João Soares do Vale ◽  
◽  
Sara Diniz ◽  
Filipe Rodrigues ◽  
◽  
...  

Chondromyxoid fibroma is rare cartilaginous tumor, accounting for 0.5% of all primary bone tumors and 2% of benign bone tumors. Areas of aneurysmal bone cysts (ABC) may be found within CMF in 8.6% of cases. A 20-year-old man presents pain due to a mass on iliopubic ramus that was diagnosed as an aneurysmal bone cyst arising from a chondromyxoid fibroma. This case confirms the rare association between aneurysmal bone cyst and chondromyxoid fibroma. Although aneurysmal bone cyst is more frequently associated with highly vascularized tumors, it is important to consider the diagnosis in the presence of chondromyxoid fibroma. Keywords: Chondromyxoid fibroma; scecondary aneurysmal bone cyst; iliopubic ramus


2021 ◽  
Vol 13 (1) ◽  
pp. 32-40
Author(s):  
A. P. Shekhtman ◽  
D. V. Rogozhin

Cranial chondroid tumors are a large group of benign and malignant neoplasms. The histological diagnosis plays a crucial role for treatment of patients with this pathology, especially, for cases of tumors with uncertain malignancy such as atypical cartilaginous tumor / chondrosarcoma grade I. There is no description of a unified concept of morphological diagnosis of atypical cartilaginous tumor / chondrosarcoma grade I with cranial localization in the current medical literature today. In this article we tried to reflect the actual state of the problem and emphasize the relevance of standardization of criteria for the histological assessment of cranial chondroid tumors.


2021 ◽  
Vol 8 ◽  
Author(s):  
Benjamin Murphy ◽  
Tharsa Thillainadesan ◽  
Kerian Robinson ◽  
Anita Clarke ◽  
Peter Choong

We report on a case of a large atypical cartilaginous tumor of the pelvis and its novel surgical resection with an anterior hemipelvectomy and reconstruction with an iliac crest graft. Surgical intervention is the mainstay treatment of pelvic chondrosarcomas. However, there have been reports of concern regarding preventing pelvic visceral herniation and adequately reconstructing the pelvis. This report is unique within the literature and has yielded good functional outcomes whilst achieving satisfactory surgical margins and minimizing morbidity.


Author(s):  
Chahnez Makni ◽  
Syrine Azza Manoubi ◽  
Olfa Bekir ◽  
Meriem Ksentini ◽  
Soumaya Rammeh ◽  
...  

2020 ◽  
Vol 6 (3) ◽  
pp. 521-525
Author(s):  
Seyed Mohammad Javad Mortazavi ◽  
Mohammadreza Razzaghof ◽  
Alireza Moharrami ◽  
Ahmad Shamabadi ◽  
Abbas Noori

2019 ◽  
Vol 32 (12) ◽  
pp. 1762-1771 ◽  
Author(s):  
Fernanda Amary ◽  
Luis Perez-Casanova ◽  
Hongtao Ye ◽  
Lucia Cottone ◽  
Anna-Christina Strobl ◽  
...  

2017 ◽  
Vol 2 (2) ◽  

Chondromyxoid fibroma (CMF) is a very rare benign cartilaginous tumor representing less than 0.5% of all bone tumors while also being the rarest cartilaginous bone tumor. Common locations of occurrence include the metaphysical region of the proximal tibia and distal femur. We report a case of a 10-year-old female affected by a CMF of the left lower tibia. The radiological features demonstrated by X-ray and magnetic resonance imaging (MRI) are discussed.


Sign in / Sign up

Export Citation Format

Share Document