scholarly journals Abnormal Movements of Japanese Infants following Treatment with Midazolam in a Neonatal Intensive Care Unit: Incidence and Risk Factors

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Mitsuru Irikura ◽  
Eri Minami ◽  
Yoichi Ishitsuka ◽  
Akihiko Kawase ◽  
Yuichi Kondo ◽  
...  

Background. This study was conducted to investigate the incidence of, and factors associated with, myoclonus-like abnormal movements of Japanese infants following treatment with midazolam in a neonatal intensive care unit (NICU). Methods. We retrospectively investigated abnormal movements and associated risk factors in Japanese infants (less than 1 year old) who received continuous intravenous midazolam treatment in the NICU of the Neonatal Medical Center, Kumamoto City Hospital, Japan, between April 2007 and March 2009. Results. The study included 94 infants who received 119 sessions of midazolam treatment in total. Nine infants (9.6%) developed abnormal movements attributable to midazolam. These nine patients had a significantly lower gestational age at birth, a significantly lower number of weeks after conception at the start of midazolam treatment, and significantly lower body weight compared with patients free of abnormal movements. Logistic regression analysis revealed neonatal asphyxia as a factor associated with an elevated risk of abnormal movements (). Conclusion. The incidence of abnormal movements after midazolam treatment was about 9.6% among the Japanese NICU infants. This result suggests that neonatal asphyxia may be involved in the onset of abnormal movements in infants treated with midazolam.

2009 ◽  
Vol 5 (4) ◽  
pp. 304-307 ◽  
Author(s):  
Li Liu ◽  
Tian Tian ◽  
Chong-Xun Zheng ◽  
Vatavu Ileana ◽  
Anca Ioana ◽  
...  

Perinatology ◽  
2019 ◽  
Vol 30 (2) ◽  
pp. 60 ◽  
Author(s):  
Young Duck Kim ◽  
Na Mi Lee ◽  
Su Yeong Kim ◽  
Dae Yong Yi ◽  
Sin Weon Yun ◽  
...  

2006 ◽  
Vol 49 (8) ◽  
pp. 845 ◽  
Author(s):  
Seung Hyun Kong ◽  
Jang Hee Kang ◽  
Kwang Su Hwang ◽  
Joong Pyo Kim ◽  
Hyeon Jung Lee ◽  
...  

2018 ◽  
Vol 1 (1) ◽  
pp. 35-45
Author(s):  
Mirjana Vucinovic ◽  
Ljubo Znaor ◽  
Ana Vucinovic ◽  
Vesna Capkun ◽  
Julijana Bandic

PURPOSE: To study the incidence of retinopathy of prematurity (ROP) in a neonatal intensive care unit in Croatia and obtain information on risk factors associated with ROP. There have been limited studies on ROP in Croatia where the screening for ROP and its treatment is still insufficient and not introduced in many intensive care units. MATERIAL AND METHODS: This retrospective study included 247 premature infants admitted to the neonatal intensive care unit of University Hospital Split, over a 5-year period between January 2012, and December 2016. In this paper the relationship between clinical risk factors and the development of ROP was analyzed. RESULTS: The overall incidence for ROP was 23,9 % (59 infants), for Type 1 ROP was 9,3% (23 infants); for Type 2 ROP was 14,6% (36 infants). Median gestational age (GA) and birthweight (BW) were significantly lower among infants with ROP versus those without ROP (29: 23-34 vs. 31: 23-34,p<0,001 and 1,180:630-2,000 vs. 1485:590-2000, p<0,001 respectively). Multivariate analysis showed that only BW (p=0,029) and small for gestational age (SGA) (p=0,045) predicted the development of ROP. CONCLUSION: Birth weight and small for gestational age were the most significant risk factors for developing ROP. In comparison with studies from highly developed countries, infants with a much wider range of gestational age and birth weights are developing Type 1 ROP. 


2015 ◽  
Vol 13 (3) ◽  
pp. 159-164
Author(s):  
İpek Güney Varal ◽  
Nilgün Köksal ◽  
Hilal Özkan ◽  
Özlem Bostan ◽  
Işık Şenkaya Sığınak ◽  
...  

2019 ◽  
Vol 34 (4) ◽  
pp. 660-662 ◽  
Author(s):  
Mónica Vizcarrondo-Oppenheimer ◽  
Cynthia García-Coll ◽  
José Martínez-González ◽  
Zayhara Reyes-Bou ◽  
Lourdes García-Fragoso ◽  
...  

Author(s):  
Chiara Ionio ◽  
Eleonora Mascheroni ◽  
Caterina Colombo ◽  
Francesca Castoldi ◽  
Gianluca Lista

Abstract Aims The aims of this study were to explore parents’ stress levels and negative feelings after premature births and to identify the risk factors related to parents’ stress and negative feelings during their children’s neonatal intensive care unit (NICU) stay. Background Preterm birth is a multi-problematic event that may put the babies in danger for both their medical and neurophysiological conditions and could have a negative impact on both the mother–father relationship and the parent–child interactions. Methods The study involved 43 mothers and 38 fathers of preterm infants. All participants filled out the Parental Stressor Scale: Neonatal Intensive Care Unit and the Profile of Mood States. Findings The results revealed significant differences between mothers’ and fathers’ responses to preterm births in terms of both stress and negative feelings. We found that, for mothers, their own young age and the baby’s need for respiratory support were significant predictors of stress; for fathers, their own young age and the baby’s lower gestational age and worse condition at birth were significant predictors of stress and negative feelings. The NICU may be a stressful place both for mothers and fathers. Identifying which mothers and fathers are at risk immediately after their children are born could help to direct specific interventions that can reduce these parents’ stress and prevent them from negative feelings.


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