Randomized, double-blind, placebo-controlled, phase I study of the safety and pharmacokinetics of namilumab in healthy Japanese and Caucasian men

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp203235 ◽

2018 ◽

Vol 56 (11) ◽

pp. 507-517 ◽

Author(s):

Shingo Tanaka ◽

Sayaka Harada ◽

Naoto Hiramatsu ◽

Ryou Nakaya ◽

Masaki Kawamura

Keyword(s):

Phase I ◽

Phase I Study ◽

Double Blind ◽

Double Blind Placebo ◽

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Randomised, Double-Blind, Placebo-Controlled, Dose-Escalating Phase I Study of QGC001, a Centrally Acting Aminopeptidase A Inhibitor Prodrug

Clinical Pharmacokinetics ◽

10.1007/s40262-013-0125-y ◽

2013 ◽

Vol 53 (4) ◽

pp. 385-395 ◽

Author(s):

Fabrice Balavoine ◽

Michel Azizi ◽

Damien Bergerot ◽

Nadia De Mota ◽

Rémi Patouret ◽

...

Keyword(s):

Phase I ◽

Phase I Study ◽

Double Blind ◽

Double Blind Placebo ◽

Aminopeptidase A ◽

Aminopeptidase A Inhibitor ◽

Dose Escalating

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First-in-human safety, tolerability, and pharmacokinetics of ammoxetine in healthy subjects: a randomized, double-blind, placebo-controlled phase I study

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2021.105724 ◽

2021 ◽

Vol 159 ◽

pp. 105724

Author(s):

Qi Shen ◽

Chao Hu ◽

Jia Miao ◽

Junxia Chen ◽

Yueying Peng ◽

...

Keyword(s):

Phase I ◽

Healthy Subjects ◽

Phase I Study ◽

Double Blind ◽

Double Blind Placebo ◽

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Pharmacokinetics, Safety, and Tolerability of Intravenous Felbinac Trometamol in Healthy Chinese Volunteers: A First-in-Human Single- and Multiple-Dose Escalation Phase I Study with a Randomized, Double-Blind, Placebo-Controlled Design

CNS Drugs ◽

10.1007/s40263-020-00739-z ◽

2020 ◽

Vol 34 (8) ◽

pp. 867-877

Author(s):

Min Wu ◽

Cuiyun Li ◽

Hong Zhang ◽

Jixuan Sun ◽

Xiaoxue Zhu ◽

...

Keyword(s):

Phase I ◽

Dose Escalation ◽

Phase I Study ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Healthy Chinese

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NXY-059 Does Not Affect Bleeding Time in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, 3-Period Crossover Phase I Study

The Journal of Clinical Pharmacology ◽

10.1177/0091270006293752 ◽

2007 ◽

Vol 47 (2) ◽

pp. 264-272 ◽

Author(s):

Dag Nilsson ◽

Johan Wemer ◽

Yi-Fang Cheng ◽

Ingalill Reinholdsson ◽

Gunnar Englund ◽

...

Keyword(s):

Phase I ◽

Healthy Volunteers ◽

Phase I Study ◽

Bleeding Time ◽

Double Blind ◽

Double Blind Placebo ◽

Crossover Phase

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Pharmacokinetics, pharmacodynamics, and tolerability of the dipeptidyl peptidase IV inhibitor LC15-0444 in healthy Korean men: A dose—block-randomized, double-blind, placebo-controlled, ascending single-dose, phase I study

Clinical Therapeutics ◽

10.1016/j.clinthera.2008.10.013 ◽

2008 ◽

Vol 30 (10) ◽

pp. 1817-1830 ◽

Author(s):

Kyoung Soo Lim ◽

Jung-Ryul Kim ◽

Yun-Jung Choi ◽

Kwang-Hee Shin ◽

Kyu-Pyo Kim ◽

...

Keyword(s):

Single Dose ◽

Phase I ◽

Phase I Study ◽

Dipeptidyl Peptidase ◽

Dipeptidyl Peptidase Iv ◽

Double Blind ◽

Double Blind Placebo

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Safety profile of the SQ house dust mite sublingual immunotherapy-tablet in Japanese adult patients with house dust mite-induced allergic asthma: a randomized, double-blind, placebo-controlled phase I study

Journal of Asthma ◽

10.1080/02770903.2018.1541353 ◽

2018 ◽

Vol 56 (12) ◽

pp. 1347-1355 ◽

Author(s):

Kazuhiro Okamiya ◽

Hisakuni Sekino ◽

Ryuji Azuma ◽

Minoru Kudo ◽

Miyuki Sakaguchi ◽

...

Keyword(s):

Phase I ◽

House Dust Mite ◽

Safety Profile ◽

Phase I Study ◽

Sublingual Immunotherapy ◽

Japanese Adult ◽

Double Blind ◽

Double Blind Placebo ◽

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Sa1767 - Eb8018, a Novel Fimh Blocker is well Tolerated in a Randomized, Double-Blind, Placebo -Controlled Phase I Study in Healthy Volunteers

Gastroenterology ◽

10.1016/s0016-5085(18)31591-9 ◽

2018 ◽

Vol 154 (6) ◽

pp. S-387

Author(s):

Jaikrishna Patel ◽

Jean-Michel Paillarse ◽

Patricia Françon ◽

Arnaud Laveissière ◽

Christophe Bonny ◽

...

Keyword(s):

Phase I ◽

Healthy Volunteers ◽

Phase I Study ◽

Double Blind ◽

Double Blind Placebo

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Faculty Opinions recommendation of A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2997965.2675063 ◽

2010 ◽

Author(s):

Johann Gudjonsson

Keyword(s):

Monoclonal Antibody ◽

Phase I ◽

Phase I Study ◽

Interferon Alfa ◽

Double Blind ◽

Double Blind Placebo

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A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti–interferon-alfa monoclonal antibody, in subjects with chronic psoriasis

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2009.05.042 ◽

2010 ◽

Vol 62 (3) ◽

pp. 427-436 ◽

Author(s):

Robert Bissonnette ◽

Kim Papp ◽

Catherine Maari ◽

Yihong Yao ◽

Gabriel Robbie ◽

...

Keyword(s):

Monoclonal Antibody ◽

Phase I ◽

Phase I Study ◽

Interferon Alfa ◽

Double Blind ◽

Double Blind Placebo

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Safety, tolerability, pharmacokinetics, and food effect of baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled, single-dose phase I study

Journal of Ethnopharmacology ◽

10.1016/j.jep.2021.114052 ◽

2021 ◽

Vol 274 ◽

pp. 114052

Author(s):

Ruihua Dong ◽

Lijun Li ◽

Hongzhi Gao ◽

Kun Lou ◽

Hongmei Luo ◽

...

Keyword(s):

Single Dose ◽

Phase I ◽

Phase I Study ◽

Food Effect ◽

Single Center ◽

Double Blind ◽

Double Blind Placebo ◽

Healthy Chinese ◽

Chinese Subjects

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