scholarly journals Case report: MPN-eo with balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11), responding to low dose imatinib

2021 ◽  
Vol 8 (3) ◽  
pp. 1
Author(s):  
Karolien Beel ◽  
Geneviève Ameye ◽  
Wim De Kelver ◽  
Lucienne Michaux
Keyword(s):  
Case Report ◽  
Young Patient ◽  
Low Dose ◽  
Treatment Initiation ◽  
Fusion Gene ◽  
Myeloproliferative Neoplasm ◽  
Molecular Test ◽  
Molecular Remission

We present a young patient with a rare eosinophilic myeloproliferative neoplasm MPN-eo with a balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11). This fusion gene was reported in only one other case in 2015. A personalized molecular test was developed with the diagnostic material of the patient. Our patient is in complete cytogenetic and molecular remission under low dose imatinib, two years after treatment initiation.

scholarly journals Complete hematological and major molecular response through treatment with ultra-low dose Interferon alpha 2 in polycythemia vera: a case report

2021 ◽  
Author(s):  
Christoph Driessen ◽  
Christoph Noppen ◽  
Georg Boonen ◽  
Juergen Drewe
Keyword(s):  
Case Report ◽  
Polycythemia Vera ◽  
Interferon Alpha ◽  
Early Treatment ◽  
Low Dose ◽  
Interferon Α ◽  
Molecular Response ◽  
Major Molecular Response ◽  
Strong Reduction ◽  
Molecular Remission

Early treatment of polycythemia vera with ultra-low-dose interferon-α 2a is well tolerated and results in complete hematologic and major molecular remission and a strong reduction of all symptoms, especially pruritus and fatigue.

Resting Tremor during Low-dose Tricyclic Antidepressant Treatment - A case report -

2007 ◽  
Vol 20 (1) ◽  
pp. 71
Author(s):  
Young Bok Lee ◽  
Jong Taek Park ◽  
Ja Youn Jeon ◽  
Kwang Ho Lee
Keyword(s):  
Case Report ◽  
Low Dose ◽  
Antidepressant Treatment ◽  
Tricyclic Antidepressant ◽  
Resting Tremor

scholarly journals Successful treatment of hemicrania continua with a combination of low-dose indomethacin and pregabalin: a case report

2014 ◽  
Vol 54 (10) ◽  
pp. 824-826
Author(s):  
Shoji Kikui ◽  
Jun-ichi Miyahara ◽  
Yoshihiro Kashiwaya ◽  
Takao Takeshima
Keyword(s):  
Case Report ◽  
Successful Treatment ◽  
Low Dose ◽  
Hemicrania Continua

scholarly journals Management of myelofibrosis during pregnancy: A case report

2015 ◽  
Vol 72 (4) ◽  
pp. 383-385 ◽  
Author(s):  
Radmila Zivkovic ◽  
Olivera Markovic ◽  
Dragomir Marisavljevic ◽  
Tatjana Terzic ◽  
Ljiljana Tukic
Keyword(s):  
Case Report ◽  
Myeloproliferative Neoplasm ◽  
Primary Myelofibrosis ◽  
Normal Pregnancy ◽  
Hematologic Malignancies ◽  
Low Molecular Weight ◽  
Dose Aspirin ◽  
Low Dose Aspirin ◽  
Pregnancy And Delivery ◽  
Normal Baby

Introduction. Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons. Case report. We reported a 28-year-old female patient with primary myelofibrosis who had a normal pregnancy and delivery in the week 40 of pregnancy without any complications. Two years before the diagnosis of PMF she had normal pregnancy. The patient was treated with interferon-alpha and low dose aspirin during the whole pregnancy and with low-molecular-weight heparin a week before delivery and 6 weeks after. The patient had no complications during pregnancy. She delivered in term with healthy, normal baby weight. Conclusion. Decision about treatment strategy of pregnancy associated hematologic malignancies should be made for each patient individually.

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