scholarly journals Major aproaches of the use of FRP and Bio-Oss® in bone regeneration and elevation for implantology: a concise systematic review

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Edmilson da Silva Esteves ◽  
Elias Naim Kassis ◽  
Sandey Bernardes da Silva Carvalho
Keyword(s):  
Systematic Review ◽  
Bone Regeneration ◽  
Maxillary Sinus ◽  
Bone Structure ◽  
Surgical Techniques ◽  
Sinus Surgery ◽  
Autogenous Bone ◽  
Bovine Bone ◽  
Platelet Concentrates ◽  
Implant Dentistry

Introduction: In the scenario of maxillary sinus surgery for the later practice of implantology, several surgical techniques can be used to reconstruct the atrophic alveolar ridge, isolated techniques or associated with autogenous, allogeneic, xenogenous, and alloplastic biomaterials. The autogenous bone graft is the only one capable of presenting three important biological properties (osteogenesis, osteoinduction, and osteoconduction) guaranteeing a self-regenerative potential. Platelet concentrates have been proposed as regenerative materials in tissue regeneration procedures. Among the platelet concentrates proposed in the literature, there is FRP that act as autogenous platelet aggregates with osteoinductive properties. As an example of xenografts, Bio-Oss® stands out, being a bovine bone biomaterial. The excellent osteoconductive properties of Bio-Oss® lead to predictable and efficient bone regeneration, becoming an integral part of bone structure and volume. Objective: To carry out a brief systematic review of the main considerations for the use of fibrin-rich plasma and Bio Oss® in bone regeneration for implant dentistry. Methods: The survey was conducted from May 2021 to July 2021 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, following the rules of Systematic Review-PRISMA. Study quality was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: The lack of bone in the alveolar crests has been a major problem in functional aesthetic recovery in patients who have suffered dentoalveolar trauma, traumatic tooth extractions, congenital tooth loss, maxillary and mandibular pathologies, in addition to infections due to the emotional and possibility of deformity. In this context, implant dentistry stands out as a modern method of oral rehabilitation for totally or partially edentulous patients. For this method to develop properly, bone integration of the implant into the recipient bone tissue must occur. It was documented that the combination of biomaterial and FRP significantly improved bone regeneration in the peri-implant area. Placing the implant with the simultaneous use of the FRP creates a good relationship between hard tissue and soft tissue. FRP is used as an adjuvant to Bio-Oss® particles for bone augmentation in the maxillary sinus. Conclusion: Based on literary findings, it was shown that FRP is favorable for bone formation processes for dental implants, especially when combined with Bio-Oss®.

Dental Implants and Plasma Rich in Fibrine: A Wide Literary Review

2021 ◽  
pp. 34-41
Author(s):  
Carlos Fernando Almeida da Silva ◽  
Tayná Toder Santos ◽  
Idiberto José Zotarelli Filho ◽  
Elias Naim Kassis
Keyword(s):  
Bone Formation ◽  
Maxillary Sinus ◽  
Dental Implants ◽  
Case Reports ◽  
Bone Grafts ◽  
Sinus Surgery ◽  
Autogenous Bone ◽  
Platelet Concentrates ◽  
Surgical Access ◽  
Short Implants

Introduction: When a dental element is lost in the posterior region of the maxilla, there is natural reabsorption of the alveolar process and at the same time there will be pneumatization of the maxillary sinus. It will increase its volume towards the place where the roots existed and this will often make it difficult or impossible to restore implants in place. For this reason, the procedure for elevating the floor of the maxillary sinus or short implants should be performed when possible. In this context, allogeneic, xenogenous, and alloplastic bone grafts are an alternative for the treatment of bone defects in the jaws, since they avoid the need for a second surgical access. However, due to the need for processing to eliminate antigenic components, these grafts are only osteoconductive with a lower bone formation potential compared to autogenous bone grafts. Also, in this context, in the last 20 years, platelet concentrates have been proposed as regenerative materials in tissue regeneration procedures. Among the platelet concentrates proposed in the literature, PRP and FRP are found to act as autogenous platelet aggregates with osteoinductive properties. Objective: The present study aimed to conduct a wide literature review on maxillary sinus surgery using fibrin-rich plasma. Methods: Experimental and clinical studies (case reports, retrospective, prospective and randomized) with qualitative and/or quantitative analysis were included. Results: The total of 48 articles were found involving Maxillary sinus surgery, Fibrin-rich plasma, and Biomaterials, of which 22 were selected to compose the present study. Conclusion: Based on the literary findings, it was shown that the FRP is favorable for bone formation processes for dental implants, especially when combined with xenografts.

Vertical Ridge Augmentation of Edentulous Posterior Inferior Jaw Using Lumina Bone Porous Large®: A Clinical Case Report

2021 ◽  
Author(s):  
Sergio Charifker Ribeiro Martins
Keyword(s):  
Clinical Case ◽  
Autogenous Bone ◽  
Bovine Bone ◽  
Success Rates ◽  
Hydroxy Apatite ◽  
Crystalline Materials ◽  
Ridge Augmentation ◽  
Versatile Technique ◽  
Implant Dentistry ◽  
Bone Particles

The use of guided bone regeneration (GBR) has been gaining more and more ground in the field of implant dentistry, due to higher confidence in the materials available. As this is a highly versatile technique, the same biological basis-cell exclusion–can be used to treat any type of defect. Vertical augmentation in the alveolar ridge is currently treated by the GBR principle, predictably and with high success rates, using a rigid framework associated with a mix of hydroxyapatite and autogenous bone. Lyophilized bovine bone is the hydroxyapatite of choice for this condition because it allows bone volume to be maintained over a long period of time, due to its slow resorption. Another important char-acteristic found in hydroxyapatite is its porosity since it allows – in addition to graft neo-vascularization–a greater ease of cell adhesion when compared to crystalline materials. Thus, this clinical case presents the use (for the first time in the literature) of a vertical augmentation of an atrophic ridge using Criteria Lumina Bone Porous® as the hydroxy-apatite of choice for association with autogenous bone particles.

Autogenous bone combined with anorganic bovine bone for maxillary sinus augmentation: analysis of the osteogenic potential of cells derived from the donor and the grafted sites

2013 ◽  
Vol 25 (5) ◽  
pp. 603-609 ◽  
Author(s):  
Willian M. de Melo ◽  
Fabiola S. de Oliveira ◽  
Élcio Marcantonio ◽  
Marcio M. Beloti ◽  
Paulo T. de Oliveira ◽  
...  
Keyword(s):  
Maxillary Sinus ◽  
Osteogenic Potential ◽  
Autogenous Bone ◽  
Bovine Bone ◽  
Sinus Augmentation ◽  
Maxillary Sinus Augmentation

Bone Formation in the Maxillary Sinus by Using Platelet-rich Plasma: An Experimental Study in Sheep

2005 ◽  
Vol 31 (1) ◽  
pp. 2-17 ◽  
Author(s):  
Edgar Grageda ◽  
Jaime L. Lozada ◽  
Phillip J. Boyne ◽  
Nicholas Caplanis ◽  
Paul J. McMillan
Keyword(s):  
Platelet Count ◽  
Bone Regeneration ◽  
Maxillary Sinus ◽  
Platelet Rich Plasma ◽  
Test Group ◽  
Bone Allograft ◽  
Autogenous Bone ◽  
Control Group ◽  
Freeze Dried ◽  
Log Ratio

Abstract Recently, platelet-rich plasma (PRP) has been proven to be an effective regeneration adjunct when combined with autogenous bone in the reconstruction of mandibular defects. However, little is known about the effect of PRP when combined with a bone allograft in the maxillary sinus. The purpose of this study was to quantitatively evaluate the ability of PRP to enhance bone regeneration in the maxillary sinus of sheep when combined with demineralized freeze-dried bone allograft (DFDBA) and cortical cancellous freeze-dried bone allograft (CCFDBA). Ten sheep were selected for bilateral sinus augmentation DFDBA + CCFDBA + PRP (test) and DFDBA + CCFDBA (control). Five were sacrificed at 3 months and the other 5 at 6 months. Hematology tests were performed for platelet count, and histology slides were obtained for histomorphometric analysis taking 2 measures of interest: total area (square millimeters) and percentage of bone fill. Student t tests showed no significant difference between test and control groups for total area (P > .25) and percentage of bone fill (P > .80) at either 3 or 6 months. The control group showed no statistical difference for total area (P < .095) and percentage of bone fill (P < .60) between 3- and 6-month healing times. The test group, however, showed a significant increase in total area (P < .025) but not in percentage of bone fill (P < .40) for the 2 healing periods. When the treatments were compared for interactions within the animal model, no clear tendency was evident for the test group to perform in relation to the control group regarding total area (r = .766, P < .01). A moderate tendency existed between the percentages of bone filled (r = .824, P < .005). Platelet-rich plasma showed higher platelet count than did the whole blood (2 to 5 times). However, no correlation was found between the log ratio and the bone measures. Within the limitations of this study, PRP failed to enhance or accelerate bone regeneration in the maxillary sinus of sheep when combined with bone allograft.

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