The relationship between residual SYNTAX score and neutrophil / lymphocyte ratio in ST segment elevation myocardial infarction patients

The neutrophil to lymphocyte ratio (NLR) predicts adverse clinical outcomes in several cardiovascular diseases. Our aim was to investigate the association of residual SYNTAX score (rSS) with the NLR in patients (n = 613) with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention. Patients were divided into 2 groups: group 1 with low NLR (<2.59) and group 2 with high NLR (>2.59). Coronary artery disease severity was calculated for both groups besides baseline clinical and demographic variables. Receiver operating characteristic curve analysis demonstrated that NLR with a cutoff value of 2.59 had good predictive value for increased rSS (area under the curve = 0.707, 95% CI: 0.661-0.752, P < .001). The median rSS value of group 2 was higher (2.0 [0-6.0]; 4.0 [0-10.0], P < .001) compared with group 1; the number of patients with high rSS was also higher in group 2 (26 [9.7%]; 107 [31.0%], P < .001). In multivariate logistic regression analysis, the NLR (odds ratio = 3.933; 95% CI: 2.419-6.393; P < .001) was an independent predictor of high rSS. Additionally, there was a positive correlation between NLR and rSS (r = 0.216, P < .001). In conclusion, higher NLR was an independent predictor of increased rSS in patients with STEMI.

Download Full-text

The relationship between neutrophil to lymphocyte ratio and SYNTAX score in patients with ST-segment elevation myocardial infarction

Journal of Clinical and Experimental Investigations ◽

10.5799/ahinjs.01.2014.02.0391 ◽

2014 ◽

Vol 5 (2) ◽

Cited By ~ 2

Author(s):

Halit Acet ◽

Faruk Ertaş

Keyword(s):

Myocardial Infarction ◽

Neutrophil To Lymphocyte Ratio ◽

Syntax Score ◽

St Segment Elevation ◽

Lymphocyte Ratio ◽

Segment Elevation Myocardial Infarction ◽

St Segment ◽

The Relationship

Download Full-text

Systemic Immune-Inflammation Index May Predict the Development of Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction

Angiology ◽

10.1177/00033197211030053 ◽

2021 ◽

pp. 000331972110300

Author(s):

Ali Bağcı ◽

Fatih Aksoy ◽

Hasan Aydin Baş

Keyword(s):

Myocardial Infarction ◽

Characteristic Curve ◽

Contrast Induced Nephropathy ◽

Predictive Capacity ◽

St Segment Elevation ◽

Neutrophil Lymphocyte Ratio ◽

Lymphocyte Ratio ◽

Segment Elevation Myocardial Infarction ◽

St Segment ◽

Immune Inflammation

The aim of this study was to investigate the predictive capacity of a systemic immune-inflammation index (SII) in the detection of contrast-induced nephropathy (CIN) following ST-segment elevation myocardial infarction (STEMI). A total of 477 STEMI patients were enrolled in the study. The patients were divided into 2 groups according to CIN development. A cutoff point of 5.91 for logarithm-transformed SII was identified with 73.0% sensitivity and 57.5% specificity to predict CIN following STEMI. According to a pairwise analysis of receiver operating characteristic curve analysis, the predictive power of SII in detecting CIN following STEMI was similar to that of high-sensitivity C-reactive protein and better than the neutrophil/lymphocyte ratio or platelet/lymphocyte ratio. As a result, SII can be used as one of the independent predictors of CIN after STEMI.

Download Full-text

Residual SYNTAX Score Is Associated With Contrast-Induced Nephropathy in Patients With Non-ST Segment Elevation Myocardial Infarction With Preserved LVEF

Angiology ◽

10.1177/0003319720928673 ◽

2020 ◽

Vol 71 (9) ◽

pp. 799-803

Author(s):

Mehmet Kucukosmanoglu ◽

Yahya Kemal İçen ◽

Hilmi Erdem Sumbul ◽

Hasan Koca ◽

Mevlut Koc

Keyword(s):

Myocardial Infarction ◽

Left Ventricular ◽

Left Ventricular Ejection ◽

Syntax Score ◽

Contrast Induced Nephropathy ◽

Ventricular Ejection Fraction ◽

St Segment Elevation ◽

Segment Elevation Myocardial Infarction ◽

St Segment ◽

Residual Syntax Score

The purpose of this study is to investigate the relation between residual SYNTAX score (rSS) and contrast-induced nephropathy (CIN) development in patients with non-ST segment elevation myocardial infarction (NSTEMI) with normal or near-to-normal left ventricular ejection fraction (LVEF) who underwent percutaneous coronary intervention (PCI). A total of 306 patients who underwent PCI with NSTEMI were included in our study. SYNTAX scores were calculated for the periods before and after PCI. Patients were divided into 2 groups as developed CIN following PCI (CIN +) and patients did not (CIN −). Fifty-four (17.6%) of patients who were included in the study developed CIN. Age ( P = .001) and rSS ( P = .002) were significantly higher and LVEF was lower ( P = .034) in the CIN (+) group. Age ( P = .031, odds ratio [OR]: 1.031, 95% CI, 1.003-1.059) and rSS ( P = .04, OR: 1.036, 95% CI, 1.002-1.071) were independent predictors for CIN. In receiver operating characteristic analyses, when the cutoff value of rSS was taken as 3.5, it determined CIN with 79% sensitivity and 65% specificity. Contrast-induced nephropathy may develop more frequently in patients with increased rSS value. The rSS may be useful to follow-up these patients for CIN development.

Download Full-text