scholarly journals Preoperative Red Cell Distribution Width as a Predictor of Mortality in Patients After Coronary Artery Bypass Grafting

2013 ◽  
Vol 16 (1) ◽  
pp. 1-6
Author(s):  
İrfan Taşoğlu ◽  
Osman Turak ◽  
Fırat Özcan ◽  
Yunus Nazlı ◽  
Ersin Kadiroğulları ◽  
...  
2018 ◽  
Vol 21 (3) ◽  
pp. 170 ◽  
Author(s):  
Alev Kılıcgedik ◽  
Abdulrahman Naser ◽  
Ahmet Seyfeddin Gurbuz ◽  
Seyhmus Kulahcioglu ◽  
Ruken Bengi Bakal ◽  
...  

Background: The use of the CHA2DS2-VASc scoring system and red cell distribution width (RDW) as post-op Atrial Fibrillation (POAF) predictors may be promising for the identification of patients that are at a higher risk of POAF.Methods: A total of 358 patients (57 patients with POAF, and 301 patients with non-POAF ) with sinus rhythm undergoing a coronary artery bypass graft (CABG) operation were included in the study retrospectively. Preoperative RDW levels and electrocardiograms with sinus rhythm were recorded. Patients with at least one 12-lead electrocardiogram with atrial fibrillation in the postoperative period, with or without medical or electrical cardioversion, were considered to have postoperative atrial fibrillation. A CHADS2 and CHA2DS2-VASc score was calculated for all of the patients.Results: RDW levels were significantly higher in POAF group. RDW levels were significantly correlated with CHADS2 ( r = 0.15, P = .007) and CHA2DS2-VASc (r = 0.19 P = .0001) scores. CHA2DS2-VASc scores were significantly higher in patients with POAF, whereas CHADS2 scores did not differ between groups. In multivariate analysis, left atrial diameter (LAD) (OR:2.44 [95% CI 1.16 – 5.1], P = .018), age (OR:1.04 [95% CI 1.01 – 1.08], P = .01), and RDW (OR:1.16 [95% CI 1.0 – 1.36], P = .05) were found to be predictive for POAF. The area under the receiver-operating characteristic curve of RDW was 0.65 (0.57 – 0.72, P = .0001) with 68.4% sensitivity and 51.2 % specificity to predict POAF.Conclusion: Our study showed that age, LAD, and the reduced probability of RDW are predictors of POAF, and that RDW is strongly associated with the thromboembolic risk as determined by CHADS2 and CHA2DS2-VASc scores.


2012 ◽  
Vol 43 (6) ◽  
pp. 1165-1169 ◽  
Author(s):  
Richard Warwick ◽  
Neeraj Mediratta ◽  
Matthew Shaw ◽  
James McShane ◽  
Mark Pullan ◽  
...  

2013 ◽  
Vol 165 (2) ◽  
pp. 369-371 ◽  
Author(s):  
Umberto Benedetto ◽  
Emiliano Angeloni ◽  
Giovanni Melina ◽  
Calogera Pisano ◽  
Andrea Lechiancole ◽  
...  

2020 ◽  
Vol 40 (4) ◽  
Author(s):  
Jing Wan ◽  
Peiwen Luo ◽  
Xiaonan Du ◽  
Hong Yan

Abstract We assessed the relationship between red blodd cell distribution width (RDW) and postoperative cognitive dysfunction (POCD) after coronary artery bypass grafting (CABG) in patients who usually had obvious hemodynamic changes. We enrolled 362 coronary heart disease patients who received CABG. POCD was assessed through neuropsychological examination at 21 days after operation. Demographics, history of diseases, blood biochemical parameters and perioperative data were collected. The receiver operating characteristic (ROC) curve was used to find the best cut-off value of RDW for diagnosis of POCD. Logistic regression was used to explore the relationship between RDW and POCD. The 21-day incidence of POCD in patients receiving CABG was 27.1% (98/362). The RDW of POCD patients was significantly higher than in the non-POCD patients (17.4 vs. 13.2). The sensitivity and specificity of RDW for predicting POCD were 82.7 and 64.8%, respectively. The POCD patients also tended to be older and had higher fasting plasma glucose, hypersensitive c-reactive protein, tumor necrosis factor-α, white blood cell levels and longer surgery time. No significant differences were found in other parameters. The 21-day neuropsychological test results were better in the POCD patients than the non-POCD patients. After adjustment of potential factors, the preoperative high RDW was still associated with an increased risk of POCD (odds ratio (OR) = 2.52, 95% confidence interval (CI): 1.28–4.31). Our study indicates that preoperative RDW is significantly elevated in POCD patients receiving CABG. The elevated preoperative RDW is associated with an increased risk of POCD and preoperative RDW can be an independent predictor of POCD.


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