Review and characteristics of 585 salivary gland neoplasms from a tertiary hospital registered in the Polish National Major Salivary Gland Benign Tumors Registry over a period of 5 years: a prospective study

2020 ◽  
Vol 74 (5) ◽  
pp. 1-6
Author(s):  
Krzysztof Piwowarczyk ◽  
Ewelina Bartkowiak ◽  
Hanna Klimza ◽  
Grażyna Greczka ◽  
Małgorzata Wierzbicka
Keyword(s):  
Salivary Gland ◽  
Needle Aspiration ◽  
Tertiary Hospital ◽  
Tumor Location ◽  
Salivary Gland Neoplasms ◽  
Benign Tumors ◽  
Tumor Diameter ◽  
Major Salivary Gland ◽  
Needle Aspiration Cytology ◽  
A Prospective Study

<b>Introduction:</b> A Polish National Major Salivary Gland Benign Tumors Registry (SGR) is a report of benign salivary gland neoplasms (SGNs) from 26 different centres in Poland, introduced in 2014. The aim of this study is to analyze demographic characteristics and clinico-pathological factors of benign SGNs treated in large tertiary institutions and to determine possible correlations between selected variables. <br><b>Material and method:</b> Analysis of 585 patients recorded in SGR and operated on for SGNs in the Department of Otolaryngology and Laryngological Surgery, University of Medical Sciences, Poznań, Poland, over a 5-year period. Patient age, sex, occupation, place of residence, tumor location, size, histology, recurrence, facial nerve function after surgery, wound healing, surgery procedure, availability of pre-operative imaging examinations, fine-needle aspiration cytology (FNAC) results were analyzed. <br><b>Results:</b> 338 females and 247 males with a mean age of 53 years were operated on. In total, 96.2% of tumors originated from the parotid and 3.8% from the submandibular gland. The most frequent primary tumor diameter was 2–4 cm (59.5%) followed by <2 cm (29.2%) and >4 cm (8.4%). Tumors of over 4 cm were frequently removed by partial superficial parotidectomy, while those under 2 cm – by extracapsullar dissection (ECD). Pleomorphic adenomas (PA) were predominant (58.8%), followed by Warthin’s tumor (WT) – 37.1%. Patients with WT were on average 13.3 years older than patients with PA. <br><b>Discussion:</b> This research can be helpful to better understand the clinico-pathological features of SGNs. Long-termin hospital-based analysis is important for subsequent metaanalyses and comparisons with other centers. The reasons why not all patients’ data are reported to the national SGR should be further precisely analyzed.

Major salivary gland tumors in children — diagnostic and therapeutic difficulties

Open Medicine ◽  
2012 ◽  
Vol 7 (5) ◽  
pp. 624-627
Author(s):  
Rafal Zielinski ◽  
Anna Zakrzewska
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Treatment Method ◽  
Needle Aspiration ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Major Salivary Gland ◽  
Tumor Treatment ◽  
Total Parotidectomy ◽  
Operational Methods

AbstractMajor salivary gland tumors are very rare in the developmental period. Confirming tumor changes of the salivary gland requires precise diagnostic imaging involving an ultrasonography scan, computed tomography and magnetic resonance. A needle aspiration biopsy (NAB) of a tumor is of high importance. Excision of the tumor is the main treatment method in the case of parotid gland tumors. Statistical data concerning tumors suggest choosing less invasive methods, which seems very logical in children. The operational methods used in the tumor treatment are: extracapsular excision of a tumor, partial parotidectomy, total parotidectomy, sometimes proceeded with lymphatic nodes operations. Extracapsular excision of a tumor is a noninvasive method chosen because of simplicity and lesser risk of serious complications. This method is reserved only for the cases of benign tumors of the gland. Most authors, however, consider a partial parotidectomy as a method of choice in benign tumor cases and a total parotidectomy in cases of carcinomas of the parotid gland. Submandibular gland tumors need total gland excision. The clinical cases presented in this paper show the difficulties in diagnosis and treatment choices in cases of major salivary gland tumors in children.

scholarly journals Cytomorphological Spectrum of Salivary Gland Lesions by Fine Needle Aspiration Cytology

2021 ◽  
Vol 8 (7) ◽  
pp. 397-401
Author(s):  
Mayur Ambekar ◽  
Rachana Binayke
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Minor Salivary Gland ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neoplastic Lesions ◽  
Needle Aspiration Cytology ◽  
A Prospective Study

Introduction: Salivary gland lesions encompass a baffling subset of lesions with overlapping morphologies on cytomorphology, due to their heterogenous histologies and rare enough to sometimes bewilder even the most knowledgeable cytopathologists. The technique of fine needle aspiration (FNA) cytology in the evaluation of salivary gland lesion is simple to perform, saves time, reliable, safe and inexpensive. FNA is highly accurate when used in proper clinical setting and supported by appropriate clinical and relevant diagnostic data. Rapidity of obtaining a pathological diagnosis allows more intelligent therapeutic approach. Materials and Methods: It was a prospective study carried out in the cytology section of pathology department for a period of two years using fine needle aspiration as a diagnostic tool as per standard protocol. The clinical and radiological data were obtained from the patient’s case papers and collaboration with the operating surgeon, the lesions were analysed on cytology. Haematoxylin & Eosin, Papanicolaou stain and Giemsa were used as standard stains. Results: A total of 66 cases of salivary gland lesions were aspirated for a period of two years. Majority of cases were in the age group of 21-30 years with 36 male patients (55%) and 30 female patients (45%). About 44(66.7%), 19(28.8%), 1(1.5%) and 2(3.0%) cases occurred in parotid gland, submandibular gland, sublingual gland and minor salivary gland respectively. There were 21(32%) cases of non-neoplastic lesions and 45(68%) cases of neoplastic lesions. Histopathological specimens were available in 11 out of 66 cases and showed correlation with cytological findings. Conclusion: Fine needle aspiration cytology of salivary gland lesions has high diagnostic accuracy, helps in appropriate therapeutic management and is useful as a diagnostic procedure because of the availability of earlier diagnosis in comparison with the histopathology. Keywords: Salivary gland lesions, fine needle aspiration cytology, neoplastic, non-neoplastic.

scholarly journals A comparative study between fine needle aspiration cytology findings and histopathological report of major salivary gland neoplasm in a tertiary hospital of Bangladesh

2014 ◽  
Vol 39 (2) ◽  
pp. 69-73 ◽  
Author(s):  
AHMZ Huq ◽  
M Aktaruzzaman ◽  
MA Habib ◽  
MS Islam ◽  
ASA Amin
Keyword(s):  
Salivary Gland ◽  
Submandibular Gland ◽  
False Negative ◽  
Needle Aspiration ◽  
Salivary Gland Neoplasm ◽  
Major Salivary Gland ◽  
Female Ratio ◽  
Parotid Tumour ◽  
Negative Results ◽  
Needle Aspiration Cytology

Salivary gland tumours are relatively uncommon and most of the tumours arise from parotid gland. Fine needle aspiration cytology (FNAC) is advised preoperatively as diagnostic tool but sometimes found to shown both false positive and false negative results. This study was aimed to find out distribution of neoplasm of major salivary glands and also to explore the sensitivity and specificity of FNAC. The present cross sectional study was done in the Dept. of Otolaryngology Head and Neck Surgery, BSMMU from January 2007 to December 2008. A total number of 60 gender-matched patients with major salivary neoplasm, confirmed by FNAC, were recruited in the study. Operated salivary gland specimens were sent for histopathological examination, histopathological findings were compared. Overall male to female ratio was 1:1. Out of 60 cases, 47 (78.3%) patients had parotid and 13 (21.7%) patients submandibular gland neoplasm. Male to female ratio for parotid tumour was1:1.1 and for submandibular 1.6:1. Mean age of the patients was 44.5 with range of 14-85 years. Of the total 60 cases 47 (78.3%) were benign and 13 (21.7%) malignant. Out of 47 parotid tumour 85.1% were benign and 14.9% malignant. Among the parotid tumour 97% were superficial lobe and 3.0% deep lobe. In case of submandibular gland 53.84% were benign and 46.15% tumour malignant. According to the sides of involvement, 25 (53.2%) cases of parotid neoplasm tumour were in the left and 22(46.8%) the right. In submandibular gland the distribution was 7 (53.8%) and 6 (46.16%) respectively. Statistically incidence of parotid tumour was significantly higher than submandibular tumour (p<0.05). Out of 60 cases in 56 (93.3%) preoperative FNAC and postoperative histopathological findings were same. There was 1.7% false positive and 5% were false negative results. Sensitivity, specificity of FNAC were 80% and 97.8% respectively. Positive predictive value was 92.3% and negative predictive 93.6% for FNAC.FNAC though cheap and safe but its diagnostic accuracy was 93.3%.Histopathologial examination remained to be of value for diagnostic confirmation of major salivary gland neoplasm. DOI: http://dx.doi.org/10.3329/bmrcb.v39i2.19645 Bangladesh Med Res Counc Bull 2013; 39: 69-73

scholarly journals Evaluation of salivary gland tumors- clinically radiologically and pathologically: prospective study

2021 ◽  
Vol 7 (4) ◽  
pp. 575
Author(s):  
Namita Mishra ◽  
Neeta Sharma
Keyword(s):  
Salivary Gland ◽  
Diagnostic Accuracy ◽  
Clinical Presentation ◽  
Malignant Tumors ◽  
Needle Aspiration ◽  
Salivary Gland Tumors ◽  
Benign Tumors ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<p><strong> </strong></p><p class="abstract"><strong>Background: </strong>Salivary gland tumors are difficult to differentiate based solely on clinical presentation or cytological findings due to their overlapping pictures. Often inadequate samples from cytology pose a challenge in preoperative diagnosis. Histopathology is considered the gold standard in diagnosing these tumors. The purpose of this study was to determine clinical, radiological, and cytological findings of these tumors and to assess the accuracy of these results with that of histopathological diagnosis.</p><p class="abstract"><strong>Methods: </strong>Prospectively 52 patients with salivary gland swellings were enrolled between 2007-2009. Cases with inflammatory swelling were excluded from the study. Demographic, clinical history, preoperatively ultrasonography, cytology, and histopathological data were collected and analyzed.</p><p class="abstract"><strong>Results: </strong>Most cases (65.38%) had parotid gland involvement. Benign tumors were common (80.76%) with pleomorphic adenoma as the most common one. Malignant tumors comprised 19.23%. Mucoepidermoid carcinoma and adenoid cystic carcinoma were common malignant tumors. Local swelling was the most common clinical presentation, and no facial nerve involvement was reported. The hard palate was the most common minor salivary gland affected predominantly by benign tumors. The diagnostic accuracy of fine-needle aspiration cytology was 96.15%, followed by clinical and radiological diagnostic accuracy of 92.31% and 86.54%, respectively. Using McNemar's test, a significant agreement was found between clinical and histological diagnosis (p=0.1336) and between FNAC and histological diagnosis (p=0.4975).</p><p class="abstract"><strong>Conclusions: </strong>Fine needle aspiration cytology is a highly accurate, sensitive, and specific screening technique. It is safe and reliable, though minimally invasive. Ultrasonography-guided cytology along with clinical, and radiological findings could enhance the pre-operative diagnostic accuracy in distinguishing salivary gland tumors.</p>

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